Clinical trials
Observational Study clinical trials
Below are recruiting observational study clinical trials, each written for real people, not researchers. We’re tracking 824 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05293184Recruiting
Angelman syndrome registry to track symptoms worldwide
This trial is building a global registry for people diagnosed with Angelman syndrome. It helps researchers learn more about how symptoms change over time, which can support future studies and treatments.
Cairns, QueenslandAges Any age - NCT05266872Recruiting
Earlier diagnosis and better treatment study for Parkinson’s
This study is looking to improve how Parkinson’s and related brain conditions are identified and treated sooner. You may be asked to share your health information and provide blood or other samples, and possibly have procedures like a spinal fluid test or a small skin sample.
LuxembourgAges 18 years+ - NCT05213572Recruiting
Deep health check study for adults with sickle cell disease
This study looks at how major organs like the brain, kidneys, heart, and liver are affected in adults with sickle cell disease, whether they've had a bone marrow transplant or gene therapy, or are continuing regular treatment. You'll get detailed tests that can help doctors understand the disease better, which may lead to improved care.
Bethesda, MarylandAges 18–100 - NCT05245695Recruiting
Endometriosis test using deep computer learning during surgery
This trial studies whether a computer (deep neural network) can better identify endometriosis in people with long-lasting pelvic pain using information from surgery. It may help doctors sort who has endometriosis more accurately when surgery is already planned.
Chandler, ArizonaAges 14–50 - NCT05195697Recruiting
Study of outcomes for adults needing urgent surgery
This study looks at what factors affect outcomes for adults admitted for urgent (acute) surgical care at Skåne University Hospital. It may help the hospital improve care and understand which patients are at higher or lower risk.
Malmö, Skåne CountyAges 18 years+ - NCT05069441Recruiting
Predicting breathing trouble after removing a breathing tube
This study looks at patients who are ready to have their breathing tube removed and checks how to predict who might struggle after extubation. It’s observational, meaning your care won’t be changed—researchers are gathering information to improve future predictions.
ChongqingAges 18 years+ - NCT05046613Recruiting
Pregnancy outcomes after rimegepant use for migraine
This observational study looks at health outcomes for moms, babies, and infants after rimegepant is used during pregnancy for migraine. It may help doctors understand potential risks or reassuring safety information for future pregnancies.
Wilmington, North CarolinaAges birth+ - NCT02792075Recruiting
Study heart artery narrowing seen on special imaging
This study follows people who already have a heart artery imaging test to understand what the imaging means for future heart outcomes. It may help doctors predict prognosis and guide treatment for coronary narrowing.
Seoul, Songpa-guAges 19 years+ - NCT02829437Recruiting
Study of endometrial stromal tumors in everyday care
This is an observational study for people diagnosed with an endometrial stromal tumor (a specific type of uterine tumor). It mainly aims to learn more about the condition in real-world patients, and helps researchers better understand how these tumors behave.
Meldola, FCAges 18–80 - NCT04845893Recruiting
Study of Ewing and related bone cancers
This is an observational study that follows people with Ewing’s sarcoma of the bone and certain “Ewing-like” tumors. It helps doctors understand the extent of disease at diagnosis and track outcomes, which may guide better planning for future care.
Rozzano, MIAges birth–49 years - NCT04890067Recruiting
Study of localized high-grade bone cancer in younger patients
This is an observational study (it mainly watches and records care) for people with high-grade osteosarcoma in an arm or leg. It may help doctors learn which care approaches work best for younger patients with localized disease.
Aviano, PordenoneAges Up to 40 years - NCT04918329Recruiting
Digestive symptom check-in study for adults
This study follows adults with long-lasting “functional” digestive symptoms as part of routine care. It may help researchers better understand these conditions and improve how they are managed.
RouenAges 18 years+ - NCT04851678Recruiting
Study how stress affects adults with Tourette syndrome
This study follows adults with Tourette syndrome over time to better understand how stressors affect symptoms and daily life. It may help researchers learn what factors make symptoms better or worse and improve future care.
Nashville, TennesseeAges 18 years+ - NCT04786977Recruiting
Measuring a nerve-related eye signal in children on vincristine
This study checks how children’s pupil responses look while they are receiving vincristine (a cancer medicine). The goal is to learn whether a simple eye measurement can reflect how the body is responding to treatment.
Washington D.C., District of ColumbiaAges 6–18 - NCT04660955Enrolling by invitation
10-year follow-up MRI after ACL surgery in young athletes
This study uses an MRI scan to look at knees 10 years after ACL reconstruction. It helps researchers understand how the knee changes over time after sports-related ACL injury, and how well reconstruction lasts.
Cleveland, OhioAges 22–45 - NCT04561518Recruiting
Study of people with TTR amyloidosis worldwide
This is an observational study (no study drug) for people with transthyretin (TTR)–mediated amyloidosis, including people who carry certain gene changes before symptoms begin. It may help researchers better understand how the disease affects health over time and what to measure in future treatments.
La Jolla, CaliforniaAges Any age - NCT04564989Recruiting
Biomarker study for HPV-related throat cancer outcomes
This observational study checks how well a blood test for HPV DNA (and other tumor genetic markers) predicts outcomes in certain throat cancers. It may help doctors better track the disease and plan treatment, because the trial validates these lab signals against real-world results.
Rochester, MinnesotaAges 18 years+ - NCT04330599Recruiting
COVID-19 study following people in the UK
This observational study follows how COVID-19 affects people in the UK over time. It may help researchers understand patterns of illness and health changes, without testing a new treatment.
London, County (optional)Ages 16 years+ - NCT04291612Recruiting
Observational study of standard surgery for uterine cancer in women
This is a research study that looks at outcomes in women with endometrial (uterine) cancer who receive the usual standard surgery. Researchers will group patients based on the final surgical and pathology results and what additional (if any) treatment is recommended afterward.
Hartford, ConnecticutAges 18 years+ - NCT04318366Recruiting
Study of COVID-19 samples and how patients respond to treatment
This trial collects and studies COVID-19 test results and other patient information to better predict treatment response and outcomes. Your sample(s) help researchers understand who may improve, worsen, or need different care.
Milan, LombardyAges 18 years+ - NCT00733590Recruiting
Study after ICD generator replacement for heart attack patients
This study follows people who had a prior heart attack and later received a replacement ICD (a device that helps prevent sudden dangerous heart rhythms). It is observational, meaning it mainly looks at outcomes and device-related information rather than testing a new drug.
Washington D.C., District of ColumbiaAges 18–85 - NCT04027777Recruiting
Study of a wearable blood pressure device in adults
This observational study tests how well a wearable device (the Aktiia bracelet) measures blood pressure by comparing it to standard listening checks. It may help people understand how accurate home-style blood pressure readings can be in different health situations.
LausanneAges 21–85 - NCT04111692Recruiting
Watching foam treatment for cysts in autosomal polycystic disease
This study follows adults with inherited kidney and/or liver cysts that are causing symptoms to see how a foam sclerotherapy procedure may help and what outcomes happen over about a year. You may be eligible if you have a few sizable, specific-type cysts and can safely attend follow-up visits.
Rochester, MinnesotaAges 18–100 - NCT04117100Recruiting
Study registry for advanced endoscopy treatments
This study keeps a record of people who choose an advanced endoscopy procedure (like ESD, EMR, advanced polypectomy, POEM, or treatment for Zenker’s). It aims to learn about real-world outcomes and safety, which may help improve care for future patients.
Montreal, QuebecAges 18 years+
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Common questions
- Are there clinical trials for observational study?
- Yes. Clin2 currently lists 824 recruiting observational study studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a observational study trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a observational study trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.