Clinical trials
Obsessive-Compulsive Disorder clinical trials
Below are recruiting obsessive-compulsive disorder clinical trials, each written for real people, not researchers. We’re tracking 107 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04899687RecruitingPhase 2
Dextromethorphan for OCD and related anxiety conditions
This trial studies dextromethorphan, a medicine sometimes used for cough, to see if it can reduce symptoms in OCD and similar conditions. It may help people whose intrusive thoughts or related worries are still challenging despite current care.
Stanford, CaliforniaAges 18–65 - NCT04900064Recruiting
Self-help CBT added to primary care behavioral health
This trial studies whether adding a Swedish self-help version of “CBT” (a structured talking-therapy approach) improves care for adults getting behavioral health support in primary care. It may help people who want support for mental health without needing fully guided therapy sessions.
Varberg, Halland CountyAges 18 years+ - NCT04934007Recruiting
Brain stimulation for OCD after medicines didn’t work
This trial studies a non-surgical brain stimulation treatment (rTMS) delivered to both sides of the brain for people with obsessive-compulsive disorder (OCD). It may help those whose OCD has not improved after trying at least two different OCD medicines.
ParisAges 18–65 - NCT04958096Recruiting
Brain stimulation study for severe OCD symptoms
This trial studies a form of brain stimulation to help reduce severe obsessive-compulsive disorder (OCD) symptoms. It may be an option if your OCD has not improved despite several standard treatments and therapy.
San Francisco, CaliforniaAges 22–75 - NCT05160129Recruiting
Deep brain stimulation for severe OCD using targeted electrodes
This study tests a deep brain stimulation (DBS) treatment device for adults with severe, long-lasting obsessive-compulsive disorder (OCD) that has not improved with standard treatments. It may help reduce OCD symptoms and improve daily functioning when medications and therapy have not worked.
New York, New YorkAges 18 years+ - NCT05224414Recruiting
Study of how thinking styles may affect OCD treatment response
This study looks at how your interpretation of unclear situations may influence how well OCD treatment works. You’ll likely complete a computer task to understand thinking patterns and response to the main OCD study protocol.
Belmont, MassachusettsAges 18 years+ - NCT05467683Recruiting
Breathing CO2 test to predict which anxiety therapies won’t work
This study uses a controlled breathing test (inhaling CO2 or breathing faster) to see if it can predict whether exposure-based therapy will help your anxiety disorder. If you are in the right group, the results may help doctors choose more effective treatment earlier.
Boston, MassachusettsAges 18–70 - NCT05520398Recruiting
Brain-targeting study of why OCD treatments may fail
This study looks at brain signals to understand why OCD treatments may not work for some people. If you have OCD and are about to start OCD therapy, you may be invited to take part.
LondonAges 18–55 - NCT05577585Recruiting
Ketamine treatment for obsessive-compulsive disorder symptoms
This study tests whether ketamine can reduce obsessive-compulsive disorder (OCD) symptoms and how it affects stress and thinking. It also compares ketamine to usual care to see if benefits and side effects differ.
Vienna, State of ViennaAges 18 years+ - NCT05577598Recruiting
Brain scan study of deep brain stimulation in OCD
This trial uses a special PET scan to see how brain sugar use changes during deep brain stimulation for obsessive-compulsive disorder (OCD). It may help researchers understand what brain activity patterns relate to treatment response.
Vienna, State of ViennaAges 18–75 - NCT05623306Recruiting
Brain stimulation surgery for OCD using a guided DBS system
This trial studies whether deep brain stimulation surgery—guided using special scans—can reduce severe obsessive-compulsive disorder (OCD) symptoms. It may help people whose OCD has not improved enough with standard medicines and therapy.
Stanford, CaliforniaAges 22–75 - NCT05651295Recruiting
Smartphone precision study to improve emotion regulation
This trial tests a precision approach delivered through a smartphone to better track and target how you manage strong emotions. It may help if you have ongoing difficulty regulating emotions day to day.
Columbus, OhioAges 18 years+ - NCT05663489Recruiting
Brain and treatment response study for anxiety and OCD
This study looks at brain-related measurements to see how people with anxiety or OCD respond to a short, intensive clinic treatment. It may help researchers understand who benefits most and why, using optional brain-scan data in some participants.
Bergen, VestlandAges 16 years+ - NCT05712057Recruiting
Brain stimulation vs therapy for emotion regulation problems
This trial compares a type of brain stimulation (rTMS) to therapy to help people better manage strong emotions. You may be eligible if you have ongoing difficulties with emotion control and meet specific mood, anxiety, or related symptom criteria.
Durham, North CarolinaAges 18–55 - NCT05783817RecruitingPhase 2
MDMA-assisted therapy for OCD in adults
This trial tests whether MDMA plus cognitive behavioral therapy (CBT) can reduce OCD symptoms in adults who have tried standard OCD treatments before. You may be asked to pause certain medicines and follow specific diet/medication rules around the study session.
Palo Alto, CaliforniaAges 18 years+ - NCT05881356Recruiting
Study factors affecting people with OCD during treatment
This study looks at what helps or gets in the way for people living with obsessive-compulsive disorder (OCD) as they go through a clinical study process, including visits and required tests. Your experience could help improve how future studies are run and how patients are supported.
San Francisco, CaliforniaAges 18 years+ - NCT05906069Recruiting
Internet CBT program study for OCD patients
This trial studies whether an online version of cognitive behavioral therapy (CBT, a structured talk-therapy approach) helps people with obsessive-compulsive disorder (OCD), and tries to predict who will benefit most. It may help by improving treatment planning and matching therapy to the right person.
Braga, GualtarAges 18–65 - NCT05940324RecruitingPhase 2
Ketamine study for OCD after prior treatment failed
This Phase 2 study tests how ketamine may work quickly in people with obsessive-compulsive disorder (OCD), especially after at least one standard treatment didn’t help. If you join, you’ll need to follow study procedures like fasting before the experimental visit and not enrolling in other medication trials during the study.
Stanford, CaliforniaAges 18–65 - NCT05961306Recruiting
Testing a stepped screening plan during pregnancy and after birth
This study checks how well a step-by-step screening approach and its tools work for identifying issues during pregnancy (weeks 20–24) or in early postpartum (6–10 weeks after delivery). It may help doctors use more accurate screening to decide who needs further care.
Ghent, Oost-VlaanderenAges 18 years+ - NCT05995951Recruiting
Deep brain stimulation for severe OCD
This trial tests whether deep brain stimulation (a surgical implant that sends electrical pulses to part of your brain) can help people with severe obsessive-compulsive disorder (OCD) that has not improved with standard treatments.
Petah TikvaAges 18–75 - NCT06017713Recruiting
Brain stimulation plus exposure for stubborn OCD
This trial tests whether a gentle brain stimulation (tDCS) combined with facing your fears can help people with hard-to-treat OCD. If you've tried multiple treatments without relief, this study may offer a new option.
PoitiersAges 18–70 - NCT06173752Recruiting
How exposure therapy works for OCD
This study looks at how exposure therapy helps people with OCD. It aims to understand the mechanisms behind why this treatment is effective.
San Diego, CaliforniaAges 18–65 - NCT06262464Recruiting
OCD prevention program for at-risk adults
This study tests a program designed to prevent obsessive-compulsive disorder (OCD) in adults who may be at risk but do not yet have the condition. It's a chance to learn coping strategies early.
Cluj-Napoca, RomaniaAges 18–65 - NCT06318806Recruiting
OCD recovery study: therapy for full remission
This study tests a psychological treatment aimed at helping people with obsessive-compulsive disorder (OCD) reach full recovery. It is done remotely using your computer or phone, so you can participate from home.
Montreal, QuebecAges 18 years+
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Common questions
- Are there clinical trials for obsessive-compulsive disorder?
- Yes. Clin2 currently lists 107 recruiting obsessive-compulsive disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obsessive-compulsive disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obsessive-compulsive disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.