Clinical trials
Old Age clinical trials
Below are recruiting old age clinical trials, each written for real people, not researchers. We’re tracking 78 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03657745Recruiting
40 Hz light and brain training for Alzheimer’s
This trial tests whether a combination of 40 Hz light stimulation and cognitive (thinking) therapy can improve symptoms in people with Alzheimer’s disease. It may help by stimulating the brain and training thinking skills, while carefully checking eye and seizure history.
Miami, FloridaAges 50 years+ - NCT03895541Recruiting
Test MRI/ultrasound to measure heart stiffness in older heart failure
This study checks whether a noninvasive imaging test can measure how stiff (stiffness) your heart muscle is in older people with certain types of heart failure. It may help doctors better diagnose and sort out the type of heart failure using your scan results.
ParisAges 60–80 - NCT04416815Recruiting
eHealth coaching to help frail older adults at home
This study tests an online (eHealth) program to promote health in adults age 75+ who are living at home and have been identified as frail. It aims to support everyday well-being without hospital care, so participants can stay healthier for longer.
Gothenburg, GothenburgAges 75 years+ - NCT04715581Recruiting
Pre-surgery rehab program for frail older adults having stomach surgery
This trial studies a “prehabilitation” program—exercise and coaching before surgery—to help frail older adults recover better after major digestive cancer surgery. It may help you strengthen your body and function before the operation, which can improve outcomes after surgery.
Beijing, Beijing MunicipalityAges 65–89 - NCT04783103Recruiting
Brain scan study of stimulation for depression in older adults
This is a pilot study that uses brain imaging to see how a brain “neuromodulation” approach may affect depression in people age 65 and older. You would be screened for depression severity, medication history, and safety limits, and then be asked to keep your depression medicines stable during the study.
Jette, Brussels CapitalAges 65 years+ - NCT05242419Recruiting
Huperzine A to reduce confusion after non-heart surgery
This trial studies whether a medicine called huperzine A can reduce “postoperative delirium,” which is sudden confusion after surgery, in older adults. It focuses on people having non-heart surgery under general anesthesia for at least two hours.
Wenzhou, ZhejiangAges 75 years+ - NCT05356611Recruiting
Study for depression and mild memory thinking problems
This trial tests a program aimed at helping older adults with depression who also have mild thinking and memory difficulties. You may be asked to complete study sessions and tracking, with support for depression symptoms and thinking function.
Las Vegas, NevadaAges 60 years+ - NCT05413616Recruiting
Personalized nutrition and activity therapy for older hospital patients
This study tests whether a tailored nutrition plan plus a step-by-step exercise program can improve physical strength and performance in older adults in the hospital. It compares these interventions to the usual hospital care you would normally get.
Nijmegen, GelderlandAges 65 years+ - NCT05525039Recruiting
Vibration plus supplement trial for weak muscles and nerves
This trial studies whether a vibration treatment combined with an HMB supplement can improve weak muscle quality and reduce early nerve-to-muscle connection problems. It is mainly for older adults who already have signs of low muscle strength or function.
Hong KongAges 60 years+ - NCT05915377Recruiting
Screening for hospital confusion in older adults
This trial is testing practical ways to recognize delirium, a sudden type of hospital confusion, in older patients. It may help your care team spot confusion earlier and respond sooner.
Boston, MassachusettsAges 70 years+ - NCT06181513RecruitingEarly Phase 1
Probiotics for mild Alzheimer's disease
This study tests whether daily probiotics (beneficial bacteria) can help people with mild Alzheimer's disease. It's an early-phase trial to see if probiotics are safe and might improve thinking and memory.
NicosiaAges 65–85 - NCT06336070Recruiting
Power training for metabolic health in postmenopausal cancer survivors
This trial compares two types of exercise—muscle power training and metabolic power training—to see which better improves your body's ability to use energy and control heart function. You may qualify if you are a postmenopausal woman who has had breast cancer and is not currently active.
Valencia, ValenciaAges 35–75 - NCT06354218RecruitingPhase 2
Serplulimab plus chemoradiation for older adults with esophageal cancer
This trial tests a new immunotherapy drug called serplulimab combined with standard chemotherapy and radiation for older adults with locally advanced esophageal cancer. It aims to see if this combination can help shrink tumors and improve outcomes without prior cancer treatment.
Nanjing, JiangsuAges 75 years+ - NCT06496945Recruiting
Day programs for dementia: impact on patients and caregivers
This study looks at how adult day programs and community care affect people with dementia and their main caregivers. It hopes to find ways to support both you and your care partner better.
Edmonton & Calgary, AlbertaAges 65 years+ - NCT06517615Recruiting
Nurse home visits for older adults living alone
This study tests whether a nurse visiting you at home and providing health education can help older adults who live alone. If you are 65 or older and already get home care, you might be able to join.
KastamonuAges 65–95 - NCT06547593Recruiting
Nutrition study for frailty in older adults
This study tests a special nutrition program to help older adults who are frail become stronger and healthier. If you are between 65 and 85 and have signs of frailty, this program might help you feel better and be more active.
Beijing, Beijing MunicipalityAges 65–85 - NCT07687316Recruiting
Mental effort during light strength training in older adults
This study looks at how older adults use their mind during light strength training. Volunteers do simple exercises and answer questions about how hard they felt they were working.
Kennesaw, GeorgiaAges 65–85 - NCT06476288Enrolling by invitation
Remote Ischemic Conditioning in Older Adults Starting Exercise
This study tests a simple, non-invasive treatment called Remote Ischemic Conditioning (RIC) in older adults who have been referred to exercise. RIC involves gently restricting blood flow to the arm for short periods, which may help improve how well your body adapts to exercise.
Durham, North CarolinaAges 65 years+ - NCT04938349Recruiting
Dual-task training for memory and balance in older adults
This trial tests a type of training that challenges you to do two tasks at once to help with thinking and movement. It is for people over 55 who may have mild memory problems but do not have major brain, heart, or lung conditions.
Chicago, IllinoisAges 55 years+ - NCT06721819RecruitingPhase 3
Sleep and brain training before heart surgery to prevent delirium
This study tests whether a combination of sleep therapy, brain games, and light exercise before heart surgery can help prevent confusion or disorientation (delirium) after the operation. Participants will be asked to use a tablet and fitness tracker daily for about an hour before their surgery.
Boston, MassachusettsAges 60 years+ - NCT06751992RecruitingPhase 4
Thinking and memory with extended-release tacrolimus in kidney transplant
This study tests if switching to an extended-release form of your anti-rejection medication (tacrolimus) helps protect memory and thinking skills. It is for older adults who have had a kidney transplant at least one year ago.
Boston, MassachusettsAges 65 years+ - NCT06817239Recruiting
Low-dose esketamine for preventing confusion after surgery in older adults
This study tests whether a low dose of the medicine esketamine can help prevent confusion after surgery in older adults at higher risk. You may qualify if you are 65 or older, planning a major non-cardiac surgery, and have certain health conditions like high blood pressure or diabetes.
Fuzhou, FujianAges 65–90 - NCT06868069Recruiting
Blood pressure changes and frailty in older adults
This study looks at how blood pressure changes over time in older adults with high blood pressure, and how it relates to frailty (a state of increased weakness). The goal is to learn more about managing blood pressure in older people.
MilanAges 75 years+ - NCT06914284Recruiting
Apathy and thinking changes in older adults with bipolar disorder
This study looks at whether apathy and certain brain markers can help predict memory and thinking problems in people over 70 with bipolar disorder. If you are 70-85, have bipolar disorder, and are currently stable (no recent mood episodes), you may be able to join.
Rennes, Ile Et VilaineAges 70–85
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Common questions
- Are there clinical trials for old age?
- Yes. Clin2 currently lists 78 recruiting old age studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a old age trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a old age trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.