Clinical trials · Hartford, CT
Opioid Use clinical trials in Hartford
We’re tracking 21 recruiting opioid use studies with a site in or near Hartford — including Early Phase 1, Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Hartford
- NCT06963476Recruiting
Magnetic brain stimulation for substance use
This study uses a gentle magnetic stimulation (rTMS) to help people who are already in treatment for alcohol or opioid addiction. The goal is to see if adding rTMS can reduce cravings and improve recovery.
Hartford, ConnecticutAges 18–60 - NCT06651333Recruiting
Brain scans during opioid addiction treatment
This study uses brain scans to understand how methadone or buprenorphine treatment affects the brain, with the goal of helping people stay in treatment and avoid relapse. You would need to be recently started on one of these medications and be able to undergo MRI scans.
Hartford, ConnecticutAges 18–50 - NCT07115030Recruiting
Support program for women with opioid use disorder and past abuse
This trial tests a stepped care program for women who have experienced intimate partner violence and are in treatment for opioid use disorder. It aims to improve recovery by addressing post-traumatic stress symptoms and overall well-being.
Enfield, ConnecticutAges 18 years+ - NCT05675735Recruiting
Methadone take-home program to help people stay in treatment
This trial studies whether changing how methadone is allowed to be taken home can improve how long people stay in opioid use disorder treatment. It focuses on clinics and on adults who have already been receiving take-home methadone.
Storrs, ConnecticutAges 18 years+ - NCT06051890RecruitingPhase 4
Assessing switching to long-acting buprenorphine injection in jail
This study tests whether switching from daily buprenorphine/naloxone (Suboxone) to a long-acting injectable buprenorphine (XRB) is safe and effective for men who are unsentenced and in jail for at least 4 days. It aims to see if the injection can help continue treatment without needing daily medication.
Springfield, MassachusettsAges Any age - NCT06527820Recruiting
Talking about buprenorphine and methadone for opioid use
This trial is testing a conversation approach to help people start medication for opioid use disorder (like buprenorphine or methadone). It may be a good fit if you've had an overdose, opioid withdrawal, or other serious problem from opioid use and are not already on these medications.
Springfield, MassachusettsAges 18 years+ - NCT05138614Recruiting
Help for people with opioid use disorder and mental health needs
This trial studies a program meant to improve treatment access and support recovery for people with opioid use disorder who also have mental health symptoms. It may help if you are new to the program or recently relapsed, or if mental health symptoms have worsened—even without a relapse.
Springfield, MassachusettsAges 18 years+ - NCT06799117Recruiting
Decision Support for Opioid Addiction Treatment
This study tests a new way to help people in the emergency department who have moderate to severe opioid use disorder. It looks at using a decision-support tool to guide treatment choices.
Guilford, ConnecticutAges 18 years+ - NCT06655883RecruitingPhase 3
Testing suvorexant for insomnia in people with opioid use disorder
This study tests whether the sleep medication suvorexant (Belsomra) can help people with opioid use disorder who also have trouble sleeping. If you are stable on medication for opioid use disorder and have not used opioids in the last month, this trial may be an option for you.
New Haven, ConnecticutAges 18–70 - NCT06207162Recruiting
Brain scans and methadone treatment for opioid recovery
This study uses MRI scans over time to track brain changes in people with opioid use disorder who recently started methadone treatment. You can help researchers understand recovery patterns if you are early in your methadone journey and can commit to repeated visits.
New Haven, ConnecticutAges 18–50 - NCT06800703Recruiting
Opioid use, pain, and the brain
This study uses brain scans (MRI) to understand how pain affects people with opioid use disorder or regular opioid use, compared to healthy volunteers. It aims to find better ways to treat both pain and opioid addiction.
New Haven, ConnecticutAges 21–60 - NCT06160284RecruitingPhase 1
Psilocybin for brain healing in opioid recovery
This study tests whether psilocybin, a psychedelic substance, can help change brain connections in people recovering from opioid use disorder. It involves brain scans and careful medical monitoring to explore new treatment options.
New Haven, ConnecticutAges 25–55 - NCT05683184RecruitingPhase 1
Study medicine for opioid addiction in adults
This early-stage study tests a new approach for opioid use disorder in adults. It aims to understand safety and how the treatment may work in people with opioid addiction.
New Haven, ConnecticutAges 18 years+ - NCT01730781Recruiting
PET scan study to image cannabinoid receptors in the brain
This study uses a special brain scan (PET) to measure cannabinoid receptors—areas in the brain that interact with cannabis-like chemicals. It may help researchers better understand how these receptors relate to conditions such as schizophrenia, PTSD, opioid use disorder, or early psychosis risk.
New Haven, ConnecticutAges 18–55 - NCT05579470Recruiting
Study opioid treatment access with staff, patients, and local leaders
This study looks at how to expand opioid addiction treatment in Central Asia by gathering survey and discussion input from people with opioid dependence, people delivering treatment, and local health leadership. It may help improve how treatment programs are set up and delivered in the future.
New Haven, ConnecticutAges 18 years+ - NCT05495984Recruiting
Brain change study for mothers in opioid treatment
This study looks at whether supportive interventions can affect brain “plasticity,” or how the brain adapts, in mothers who are in treatment for opioid use disorder. If you qualify, you may be asked to take part in assessments and follow-up so researchers can better understand recovery during early motherhood.
New Haven, ConnecticutAges 21–45 - NCT05547048RecruitingPhase 4
Phone-based support to help prevent HIV in justice-involved women
This study tests an integrated phone-based health program (e-health) designed for women involved with the justice system who have opioid use disorder. It aims to help people who qualify for HIV prevention (PrEP) stay protected, especially by using simple, ongoing support through phone access.
New Haven, ConnecticutAges 18 years+ - NCT05669534RecruitingPhase 4
HIV prevention support for people starting PrEP
This study tests how to better support HIV prevention for people who inject drugs and are newly starting PrEP (medicine to prevent HIV). It focuses on people taking medication for opioid use disorder and who have mild thinking and memory problems, to help them stay safe and adhere to prevention.
New Haven, ConnecticutAges 18 years+ - NCT05957159RecruitingEarly Phase 1
Testing an alcohol brain imaging study based on opioid receptor balance
This early-phase study looks at how the brain’s opioid receptor balance may be different in people with alcohol use disorder (AUD), using brain scans and blood testing. It may help researchers understand why some people respond differently to alcohol and related treatments.
New Haven, ConnecticutAges 21–70 - NCT06544291RecruitingPhase 2
THC and CBD for pain and opioid use disorder
This study tests whether a combination of THC and CBD can help people who have both opioid use disorder and chronic low back pain. You would need to be on a stable dose of methadone and have used cannabis at least once in your life.
New Haven, ConnecticutAges 18–65 - NCT06962033Recruiting
Pride III: Prison and HIV prevention study
This study looks at ways to improve HIV prevention and treatment for people on probation who have injected opioids. Researchers want to learn from your experiences to help create better services.
New Haven, ConnecticutAges 18 years+
Hear when a new Opioid Use trial opens near Hartford, CT
We’ll email you when one opens near Hartford, CT — at most once a week, no account needed, unsubscribe anytime.
Opioid Use trials in other cities
Where these studies are running near Hartford
Institutions with a site for the recruiting opioid use studies listed above.
- Yale University · 5 studies
- Connecticut Mental Health Center · 4 studies
- APT Foundation · 2 studies
- Hartford Healthcare · 2 studies
- Baystate Health
- Baystate Medical Center
- Behavioral Health Network
- Community Health Resources (CHR) Pathways Opiate Treatment Program
What taking part in a opioid use study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting opioid use studies in Connecticut.
Common questions
- Are there opioid use clinical trials near Hartford?
- Yes. We're currently tracking 21 recruiting opioid use studies with a site near Hartford, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a opioid use study near Hartford?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Hartford to take part?
- Not necessarily. These studies have a site near Hartford, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a opioid use trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New opioid use studies open near Hartford regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.