Clinical trials
Organoids clinical trials
Below are recruiting organoids clinical trials, each written for real people, not researchers. We’re tracking 72 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06405230RecruitingPhase 1/Phase 2
Study of Immunotherapy Response in Returned Lung Cancer
This trial tests how well a new imaging method and lab-grown tumor models can predict response to immunotherapy in people with non-small cell lung cancer that has returned after initial surgery. Participants will receive standard immunotherapy, and researchers will study their tumor samples and scans.
LondonAges 30 years+ - NCT06408701Recruiting
Lab-grown eye cells from people with eye problems
This study uses stem cells from people with eye malformations to grow tiny 3D eye organ-like structures in the lab. The goal is to better understand how eye problems develop, which could lead to new treatments in the future.
Clermont-FerrandAges 6 years+ - NCT06459791Recruiting
Personalized treatment for advanced breast cancer using lab-grown tumor models
This trial tests a personalized approach to cancer treatment. Doctors will grow a ‘mini-tumor’ from a biopsy of your cancer in the lab to help find the best therapy for you. It is for people with advanced breast cancer that has not responded well to standard treatments.
ParisAges 18 years+ - NCT06468124Recruiting
Testing treatments on mini tumors for breast cancer that has spread
This trial uses a special lab technique (called organoids) to grow a mini version of your tumor from a biopsy sample. Researchers will test different treatments on these mini-tumors to see which one might work best for you.
LondonAges 18 years+ - NCT06603506Recruiting
Testing PARP inhibitors on your endometrial cancer cells
This study is testing whether a special kind of medicine called a PARP inhibitor can work against endometrial cancer cells grown in a lab from your tumor. The goal is to find out which patients might benefit from this treatment in the future.
CaenAges 18 years+ - NCT06686342Recruiting
Drug sensitivity test for recurrent or metastatic head and neck cancer
This trial uses a patient's own tumor cells grown in a lab to test which drugs are most likely to work against their cancer. It aims to help guide treatment choices for people with head and neck cancer that has come back or spread.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06686979Recruiting
Drug sensitivity test for advanced salivary gland cancer
This trial tests whether a laboratory-grown mini-tumor (organoid) from your biopsy can predict which drugs will work best for your recurrent or metastatic salivary gland cancer. You would need to provide a tumor sample and have adequate organ function.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06702800Recruiting
Using tumor models to predict breast cancer drug response
This study uses a personal lab-grown model of your tumor (called an organoid) to help predict which drugs are most likely to work for your specific breast cancer. It is open to both early-stage and advanced breast cancer patients who are about to start or are already receiving treatment.
Changsha, HunanAges 18–70 - NCT06755762Recruiting
3D blood test for advanced head and neck cancer
This study uses a special 3D culture method to grow and analyze tumor cells from the blood of people with advanced head and neck cancer. It also includes healthy volunteers for comparison, to help researchers understand how these cells behave and improve future detection.
TaoyuanAges 18–80 - NCT06786663Recruiting
Male breast cancer organoids study
This trial studies tumor samples from men with breast cancer to grow mini tumors (organoids) in the lab. The goal is to better understand male breast cancer and find personalized treatments.
RomeAges 18 years+ - NCT06787625Recruiting
Growing tumor models from colorectal cancer and liver metastases
This study takes samples from colorectal cancer that has spread to the liver and grows them in the lab. The goal is to create models that can help researchers understand the cancer better and find new treatments.
RomeAges 18 years+ - NCT06791941Recruiting
Studying therapy resistance in recurrent head and neck cancer
This study looks at why some head and neck cancers come back after treatment. It will test tumor tissue from people having surgery to see if certain proteins (mutant p53 and YAP) are linked to treatment resistance. Your participation could help researchers understand how to better treat these cancers in the future.
Roma, RomeAges 18 years+ - NCT06805890Recruiting
Tissue repair study in IBD using organoid technology
This study collects tissue samples from people with Crohn's disease or ulcerative colitis during routine colonoscopy or surgery to grow mini-organs (organoids) in the lab. The goal is to learn how the gut heals itself, which could lead to better treatments.
MarseilleAges 18 years+ - NCT06841861RecruitingPhase 1/Phase 2
Testicular organoid study for male fertility
This trial uses tiny lab-grown testicles to study sperm production. It may help men with infertility learn more about why they can't make sperm.
San Francisco, CaliforniaAges 18–60 - NCT06856252Recruiting
Studying human liver organoids for a fatty liver disease called NASH
This study takes small samples of liver tissue to grow 3D 'mini livers' (organoids) in the lab. Researchers want to learn how non-alcoholic steatohepatitis (NASH), a serious fatty liver condition, starts and progresses, which could lead to better treatments.
Milan, MilanoAges 18 years+ - NCT06907342RecruitingPhase 2
Personalized chemo selection for advanced colorectal cancer
This trial tests whether a functional test on a tumor biopsy can help choose the best first chemotherapy regimen (FOLFOX or FOLFIRI) for people with metastatic colorectal cancer. It aims to improve outcomes by matching treatment to each person's unique tumor biology.
TrondheimAges 18 years+ - NCT06959173Recruiting
Personalized treatment for fluid around the lungs
This study uses lab-grown miniature versions of your cancer cells (organoids) to find which treatment might work best for you. It's for people with fluid around the lungs caused by cancer (malignant pleural effusion).
Zhengzhou, HenanAges 18 years+ - NCT07054086Recruiting
Personalized treatment testing with tumor models for esophageal cancer
This trial tests whether a personalized treatment plan, chosen using a lab-grown model of your tumor, works better than standard therapy for esophageal cancer that can be surgically removed. It aims to find the most effective drugs for you before surgery.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07248878Recruiting
Cervical cancer organoid study using biopsy samples
This trial aims to grow miniature versions of cervical cancer tumors (organoids) from biopsy tissue. It helps researchers learn more about the cancer and potentially find better treatments, without any extra procedures beyond your standard diagnostic biopsy.
Roma, RMAges 18 years+ - NCT07260188Recruiting
Breast cancer organoids from patients before chemo
This study collects tumor tissue from breast cancer patients before they start chemotherapy to grow miniature versions of their tumors (organoids) in the lab. The goal is to understand how each tumor responds to treatment, which may help personalize future therapies.
Pavia, PVAges 18 years+ - NCT02732860Recruiting
Test your tumor’s drug response using a lab model
This trial grows a lab model from your own tumor tissue (or resected tissue) to predict which drugs might work best. It’s meant to match investigational treatments to your specific tumor biology.
Toronto, OntarioAges 18 years+ - NCT07610616Recruiting
Testing ADC Drug Effectiveness Using Lung Cancer Lab Models
This research study tests how a lung cancer drug called Trastuzumab deruxtecan (T-DXd) works by growing your cancer cells in a lab dish and studying them with your immune cells. The goal is to better understand which patients might benefit most from this treatment.
Guangzhou, GuangdongAges 18–100 - NCT07528079Enrolling by invitation
Personalized Chemotherapy for Children with Advanced Soft Tissue Tumors
This trial uses lab-grown tumor samples from your child to test which chemotherapy drugs work best for their specific cancer. The goal is to find the most effective treatment by testing medicines on their tumor cells before giving them to your child.
Shanghai, Shanghai MunicipalityAges 1–18 - NCT06786780Enrolling by invitationPhase 2
Predicting chemoradiation response with cervical cancer organoids
This trial is studying whether lab-grown mini-tumors (called organoids) from your cervical cancer biopsy can predict how well chemoradiation will work. It aims to create a tool to help doctors choose the best treatment for each patient.
Chongqing, ChinaAges 18 years+
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Common questions
- Are there clinical trials for organoids?
- Yes. Clin2 currently lists 72 recruiting organoids studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a organoids trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a organoids trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.