Clinical trials
Orthodontics clinical trials
Below are recruiting orthodontics clinical trials, each written for real people, not researchers. We’re tracking 81 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06529601Recruiting
Digital vs. traditional lower tooth retainers after braces
This trial compares two types of retainers (wire bonded to the back of your lower front teeth) after braces. One retainer is made with a digital design (CAD/CAM), the other is made the traditional way.
FlorenceAges 13–20 - NCT06302296Recruiting
Speeding up braces with your own blood
This study tests whether a special injection made from your own blood (called injectable platelet-rich fibrin) can help move your teeth faster during braces treatment. It involves removing two upper premolars and then receiving the injection to see if it speeds up straightening.
HamaAges 18–26 - NCT06315348Recruiting
Gum shaping during braces with a vibration tool
This trial tests a new, less invasive surgical technique (using a special tool that vibrates, not a scalpel) to help reshape the gums while straightening teeth with braces. It is for people who need braces for mild to moderate crowding and have healthy gums.
MadridAges 16–70 - NCT05989750Recruiting
Air-Polishing Teeth Cleaner During Braces Treatment
This study tests a special air-polishing cleaning method using erythritol (a gentle powder) during braces treatment. It may help keep teeth and gums healthier while you have braces.
Geneva, Canton of GenevaAges 12–16 - NCT05851963Recruiting
Toothbrushing help for teens with fixed braces
This study looks at whether using specific toothbrushes in daily life can improve dental gum and tooth health for teens with fixed braces. It may help by testing simple at-home brushing routines that could reduce gum problems during orthodontic treatment.
NancyAges 11–15 - NCT05573308Recruiting
Clear aligner study using remote monitoring and AI checks
This trial looks at clear braces (aligner) treatment for straightening teeth, using remote monitoring and computer-guided (AI) check-ins. It may help by making treatment progress easier to track and adjust.
Antioch, IllinoisAges 12–70 - NCT05492773Recruiting
Clear aligner treatment with tiny bone punctures to speed tooth movement
This trial tests whether a technique called tiny “micro-punctures” in the jaw bone can speed up orthodontic tooth movement in people with moderate front-lower tooth crowding. It uses clear aligners and may help teeth move faster, but only if you meet the dental and medical safety requirements.
HamaAges 18–26 - NCT05414019Enrolling by invitation
Braces study for tooth root damage in teens
This study compares different orthodontic force plans to see how they affect “root resorption,” when the tooth root shortens over time. It’s meant to find safer ways to move front lower teeth in teens who have a deep bite.
CairoAges 12–16 - NCT04117360Recruiting
Speech therapy study for people after jaw alignment surgery
This study looks at how well people can make specific speech sounds before and after jaw alignment treatment. It may help researchers understand whether speech patterns improve with treatment in people with certain bite differences.
Chapel Hill, North CarolinaAges 15–40
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Common questions
- Are there clinical trials for orthodontics?
- Yes. Clin2 currently lists 81 recruiting orthodontics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a orthodontics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a orthodontics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.