Clinical trials
Orthodontics clinical trials
Below are recruiting orthodontics clinical trials, each written for real people, not researchers. We’re tracking 84 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07264127Recruiting
I-arch system for early orthodontic treatment
This study tests a new orthodontic tool, the I-arch system, for straightening the lower front teeth when they are moderately crowded. It aims to see how well the I-arch works during the first stage of braces treatment.
KarbalaAges 12 years+ - NCT06943443Enrolling by invitation
Vitamin D and expander treatment for teens
This trial looks at whether vitamin D levels affect how well a special expander (MARPE) works to fix a narrow upper jaw in teens. If you are 15–18 and have a narrow upper jaw, you may be able to join.
Konya, MeramAges 16–18 - NCT07617480Enrolling by invitation
Orthodontic bracket bonding: acid etching with or without sandblasting
This study compares two methods of preparing tooth surfaces before attaching orthodontic brackets (the small squares glued to teeth during braces treatment). Researchers want to see which method—using acid alone or acid plus sandblasting—keeps brackets bonded better to your teeth.
DhakaAges 18–64 - NCT07234149Recruiting
Comparing tooth color change and removal time for two attachment materials
This study compares two types of tooth-colored materials used for the small bumps (attachments) placed on teeth during clear-aligner treatment. Researchers want to see which material causes less tooth staining and is easier for the dentist to remove.
Kirkuk, Kirkuk GovernorateAges 18–40 - NCT04117360Recruiting
Speech therapy study for people after jaw alignment surgery
This study looks at how well people can make specific speech sounds before and after jaw alignment treatment. It may help researchers understand whether speech patterns improve with treatment in people with certain bite differences.
Chapel Hill, North CarolinaAges 15–40 - NCT04828096Recruiting
Compare three options for long-term lower retainer care
This trial studies which type of bonded (glued-in) lower front retainer works best over time after braces. It may help by improving long-term tooth stability and outcomes for people who need a retainer after orthodontic treatment.
Barcelona, CataloniaAges 10–60 - NCT05081258Recruiting
Tests presurgery shaping for newborn cleft lip and palate growth
This study looks at whether a presurgery orthodontic shaping method affects how newborns with a cleft lip and palate grow over time. It may help clinicians decide on the best early treatment approach.
Erlangen, BavariaAges 1 day–2 years - NCT05710952Recruiting
Orthodontic braces study and how they affect jaw joints
This study looks at whether multi-attachment orthodontic treatment (either on the front or back of teeth) changes the temporomandibular joint, which is the jaw joint. The researchers will assess your jaw joint using a tool called Modjaw.
MontpellierAges 18 years+ - NCT05979805Recruiting
Education programs to prevent cavities and gum problems during braces
This study compares two types of education programs to see which better prevents cavities and gum inflammation in people getting braces. Participants must be new to orthodontic treatment and have healthy teeth and gums at the start.
BogotáAges 13–28 - NCT05989750Recruiting
Air-Polishing Teeth Cleaner During Braces Treatment
This study tests a special air-polishing cleaning method using erythritol (a gentle powder) during braces treatment. It may help keep teeth and gums healthier while you have braces.
Geneva, Canton of GenevaAges 12–16 - NCT06122805Recruiting
Electric vs. Manual Toothbrush for Kids with Cleft Lip/Palate
This study compares a special dual-light electric toothbrush to a regular manual toothbrush for kids and teens with cleft lip or palate who wear braces. The goal is to see which brush keeps teeth cleaner and gums healthier during orthodontic treatment and after oral surgery.
Los Angeles, CaliforniaAges 6–20 - NCT06302296Recruiting
Speeding up braces with your own blood
This study tests whether a special injection made from your own blood (called injectable platelet-rich fibrin) can help move your teeth faster during braces treatment. It involves removing two upper premolars and then receiving the injection to see if it speeds up straightening.
HamaAges 18–26 - NCT06315348Recruiting
Gum shaping during braces with a vibration tool
This trial tests a new, less invasive surgical technique (using a special tool that vibrates, not a scalpel) to help reshape the gums while straightening teeth with braces. It is for people who need braces for mild to moderate crowding and have healthy gums.
MadridAges 16–70 - NCT06461611Recruiting
Health diary study for teens with braces
This trial tests if keeping a health diary helps teenagers with braces take better care of their teeth and feel more in control. It is for first-time orthodontic patients aged 12 to 18.
Guangzhou, GuangdongAges 12–18 - NCT05573308Recruiting
Clear aligner study using remote monitoring and AI checks
This trial looks at clear braces (aligner) treatment for straightening teeth, using remote monitoring and computer-guided (AI) check-ins. It may help by making treatment progress easier to track and adjust.
Antioch, IllinoisAges 12–70 - NCT06602518Recruiting
Airway changes after braces for deep overbite
This study looks at how fixing a deep overbite (where top teeth cover most of your bottom teeth) with braces may affect the size of your airway (the space in the back of your throat for breathing). It helps doctors understand if treatment can also help with breathing.
AlexandriaAges 12–16 - NCT06685016Recruiting
Study of dental health after IPR with clear aligners
This study looks at how the teeth and gums are doing after a common orthodontic step called IPR (a slight smoothing between teeth) in people wearing clear aligners. It will help understand if this procedure keeps your mouth healthy.
NaplesAges 17–100 - NCT06751979Recruiting
Probiotics for people with braces
This trial tests if a probiotic can improve oral health for people with braces. It might help reduce plaque buildup around brackets and wires.
AarhusAges 10 years+ - NCT06858670Recruiting
A device to correct deep curve in back molars
This trial tests a small device (auxiliary segmental lingual appliance) placed on the inside of your lower back teeth to help correct a deep curve in your bite. It may be an option for people already in braces whose second molars tilt inward.
HanoiAges 18 years+ - NCT07086612Recruiting
Sleep apnea and dental crossbite in children
This study looks at the link between sleep apnea (pauses in breathing during sleep) and a narrow upper jaw (crossbite) in children ages 6 to 16. It may help understand if treating the jaw can improve sleep breathing.
RouenAges 6–16 - NCT07097714Recruiting
Collagen scaffold with gum surgery to improve orthodontic results
This trial tests if a special collagen scaffold placed during gum surgery can improve orthodontic treatment for people with thin gums. It may help protect the gums and bone during teeth straightening.
Novosibirsk, Novosibirsk OblastAges 18–50 - NCT07105969Recruiting
Studying coated mini-screws for tooth movement
This trial tests whether special coated mini-screws placed in the jaw can help move teeth and resist infection. It's for teens and young adults getting premolars removed as part of braces treatment.
Al Mansurah, Dakahlia GovernorateAges 16–20 - NCT07119840Recruiting
Listerine vs. chlorhexidine mouthwash during braces
This trial compares two common mouthwashes (Listerine and chlorhexidine) to see which works better for keeping your teeth and gums healthy while you have braces. If you are getting braces, you can join to help find out which rinse helps prevent plaque and gum problems.
Swāt, KPKAges 13–40 - NCT07162753Recruiting
Ethnic bias check in AI orthodontic diagnosis
This trial checks if an AI system for orthodontic diagnosis works equally well for people of different ethnic backgrounds. You may be eligible if you have a side-view face photo taken before braces or similar treatment.
Istanbul, FatihAges 4 years+
Hear when a new Orthodontics trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for orthodontics?
- Yes. Clin2 currently lists 84 recruiting orthodontics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a orthodontics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a orthodontics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.