Clinical trials
Orthodontics clinical trials
Below are recruiting orthodontics clinical trials, each written for real people, not researchers. We’re tracking 81 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06734325Recruiting
Mobile health program for braces patients
This study uses text messages on WhatsApp to help young people with braces improve their brushing habits. It will test whether a simple mobile program can keep your teeth cleaner and help you learn more about oral health.
AlexandriaAges 16–25 - NCT07534423Recruiting
Finishing teeth after braces removal training
This study teaches dental professionals best practices for completing and polishing teeth immediately after braces are removed. It's designed for orthodontists and dentists who work with braces to improve their finishing techniques.
Roma, RMAges Any age - NCT06751979Recruiting
Probiotics for people with braces
This trial tests if a probiotic can improve oral health for people with braces. It might help reduce plaque buildup around brackets and wires.
AarhusAges 10 years+ - NCT07466641Recruiting
Low-level laser or Piezocision to speed up canine tooth movement
This trial compares two treatments to see if they can safely speed up a specific tooth movement during braces. It tests a low-level laser or a minor surgical procedure called Piezocision against standard care.
Cairo, Cairo GovernorateAges 18–25 - NCT07455656Recruiting
Vitamin D3 or gum massage for faster canine movement with braces
This study tests whether applying vitamin D3 or a special gum massage (corticision) next to the teeth can help move your eye teeth (canines) faster after your upper first premolars are removed for braces. It is for teenagers or young adults who already need that extraction as part of their orthodontic plan.
Cairo, Cairo GovernorateAges 13–20 - NCT07362160Recruiting
Comparing two types of palate expanders for kids
This trial compares a newer clear palate expander to the traditional Hyrax expander in children aged 10-14 with a crossbite. The goal is to see which device works better and is more comfortable.
Baghdad, Al-Rusafa, Bab Al-moadhamAges 10–14 - NCT07355400Recruiting
NeoPill device for reducing mouth bacteria in braces patients
This trial tests a device called NeoPill to reduce bacteria in the mouths of people with braces. It involves a single visit and may help control oral bacteria levels.
LimassolAges 18 years+ - NCT07293975Recruiting
Pain relief during brace removal with TENS or vibration
This study tests two drug-free methods—gentle electrical stimulation (TENS) and high-frequency vibration—to see if they can reduce pain when braces are removed.
BaghdadAges 15–35 - NCT05979805Recruiting
Education programs to prevent cavities and gum problems during braces
This study compares two types of education programs to see which better prevents cavities and gum inflammation in people getting braces. Participants must be new to orthodontic treatment and have healthy teeth and gums at the start.
BogotáAges 13–28 - NCT07264127Recruiting
I-arch system for early orthodontic treatment
This study tests a new orthodontic tool, the I-arch system, for straightening the lower front teeth when they are moderately crowded. It aims to see how well the I-arch works during the first stage of braces treatment.
KarbalaAges 12 years+ - NCT07234149Recruiting
Comparing tooth color change and removal time for two attachment materials
This study compares two types of tooth-colored materials used for the small bumps (attachments) placed on teeth during clear-aligner treatment. Researchers want to see which material causes less tooth staining and is easier for the dentist to remove.
Kirkuk, Kirkuk GovernorateAges 18–40 - NCT07210762Recruiting
Gum cleft during canine tooth movement
This study looks at whether a small gum opening (gingival cleft) forms when a canine tooth is pulled back after premolar removal. It may help understand how gums heal during orthodontic treatment.
Karachi, SindhAges Any age - NCT07205172Recruiting
Gum looks and teeth crowding in children
This study looks at how the appearance of the gums relates to crowding of teeth in children. It will examine kids in different stages of tooth development to see if there is a link.
RomaAges 5–16 - NCT07191158Recruiting
Testing a 3D-printed molar-moving device for bite correction
This trial is testing a new 3D-printed device that moves your upper molars backward to correct a specific type of bite problem (Class II). It may help you if you have a clear overbite on both sides and your second molars are already in place.
Baghdad, Al-RussafaAges 16–30 - NCT07180849Recruiting
New fluoride varnish vs standard varnish for braces plaque
This trial compares a new fluoride varnish that contains tiny titanium particles (nanoparticles) to a standard fluoride varnish. It tests which one is better at preventing plaque buildup for people getting braces.
IslamabadAges 16–30 - NCT07155343RecruitingEarly Phase 1
Comparing two types of glue for braces in teens and adults
This early-phase trial tests if a newer, faster-setting glue (bulk-fill composite) works as well as the standard glue for attaching braces. It's for people aged 13 to 40 who are starting or continuing fixed braces treatment.
Karachi, SindhAges 13–40 - NCT07146464Recruiting
Peptide vs calcium paste for early cavity spots
This trial tests whether a new peptide treatment or a calcium-phosphate paste works better at reversing early white-spot cavities on front teeth. If you're a young adult with early decay on your front teeth, you may be able to join.
Cairo, Cairo GovernorateAges 15–25 - NCT07098325Recruiting
3d printed retainers for braces after treatment
This trial tests how your mouth reacts to a 3d printed retainer after braces. It may help you keep your teeth straight.
AsyutAges Any age - NCT07097714Recruiting
Collagen scaffold with gum surgery to improve orthodontic results
This trial tests if a special collagen scaffold placed during gum surgery can improve orthodontic treatment for people with thin gums. It may help protect the gums and bone during teeth straightening.
Novosibirsk, Novosibirsk OblastAges 18–50 - NCT07086612Recruiting
Sleep apnea and dental crossbite in children
This study looks at the link between sleep apnea (pauses in breathing during sleep) and a narrow upper jaw (crossbite) in children ages 6 to 16. It may help understand if treating the jaw can improve sleep breathing.
RouenAges 6–16 - NCT06975358Recruiting
Faster braces with gum surgery and growth factor injections
This study tests if a small gum surgery (alveolar decortication) plus a natural growth factor injection (CGF) can speed up tooth movement in people who need braces and have two teeth removed. It may help you have a shorter treatment time.
Tanta, TantaAges 16–22 - NCT06943443Enrolling by invitation
Vitamin D and expander treatment for teens
This trial looks at whether vitamin D levels affect how well a special expander (MARPE) works to fix a narrow upper jaw in teens. If you are 15–18 and have a narrow upper jaw, you may be able to join.
Konya, MeramAges 16–18 - NCT06873932Enrolling by invitation
Studying tooth movement with special aligner attachments
This trial tests whether a new type of attachment (beveled) on clear aligners works better than standard attachments for moving teeth in adults. If you are getting aligner treatment and need certain tooth movements on both sides of your mouth, this study may help improve your results.
Curitiba, ParanáAges 18 years+ - NCT06834139Enrolling by invitation
Testing a new cleaning device for people with braces
This trial tests a device called the Neo Pill to see if it helps keep teeth clean for people with braces. It compares the device to regular brushing and may help reduce plaque and gum problems during orthodontic treatment.
Kragujevac, SerbiaAges 18 years+
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Common questions
- Are there clinical trials for orthodontics?
- Yes. Clin2 currently lists 81 recruiting orthodontics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a orthodontics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a orthodontics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.