Clinical trials
Orthodontics clinical trials
Below are recruiting orthodontics clinical trials, each written for real people, not researchers. We’re tracking 81 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07718061Recruiting
Bacteria in dental plaque with orthodontic retainers
This trial studies the types of bacteria found in dental plaque from people who have orthodontic retainers after braces. It aims to understand how retainers affect oral bacteria.
MurciaAges 18–40 - NCT07868705Enrolling by invitation
Comparing small screws for braces in the upper jaw
This study compares two sizes of tiny screws (called miniscrews) that are sometimes used with braces to help move teeth. The screws are placed in the upper jaw to help correct an overbite where the top teeth stick out too far. The study looks at how well the screws work, how stable they are, and how they feel to patients.
Kuala LumpurAges 13–50 - NCT07513792Recruiting
3D imaging to prevent gum shrinkage during clear aligner treatment
This study tests whether a special 3D imaging tool helps protect your gums from pulling back (receding) while straightening your teeth with clear aligners. Gum recession can expose tooth roots and cause sensitivity, so the trial is exploring whether better visualization during treatment planning prevents this problem.
Liège, LiegeAges 18 years+ - NCT03906422Recruiting
Study of pain after placing braces archwire
This study compares how much pain people feel after their braces archwire is first put in. It may help orthodontists choose approaches that make the early pain experience easier.
Aurora, ColoradoAges 12 years+ - NCT07183111Recruiting
AI vs. regular instructions for braces patients
This trial compares standard instructions to AI-powered guidance (using a custom ChatGPT) to help patients with braces learn how to care for their teeth. It aims to see which method helps patients follow oral hygiene instructions better.
Islamabad, FederalAges 18–30 - NCT06573996Recruiting
Testing a mouth TENS device for braces pain
This trial tests if a small device placed inside the mouth can ease pain from braces. You'll receive either real or fake treatment with the TENS device to see if it helps with soreness after adjustments.
San Francisco, CaliforniaAges 12 years+ - NCT05038865Recruiting
How jaw alignment affects teens’ quality of life
This study compares how different types of bite/jaw alignment affect adolescents’ daily comfort and oral-health-related quality of life. It’s mainly done by asking teens to complete questionnaires and comparing groups with and without malocclusion.
Malmö, Skåne CountyAges 12–19 - NCT07842120RecruitingPhase 2
Can certain medications speed up tooth movement with braces?
This study tests three different treatments (MOP, prostaglandin E1, and calcitriol) to see if they can make teeth move faster during orthodontic treatment. If you're getting braces for moderate crowding, this could reduce your treatment time.
Baghdad, Baghdad GovernorateAges 18–25 - NCT07836816Enrolling by invitation
Comparing two methods for moving canine teeth in braces
This study compares two ways of retracting the canine teeth after premolar removal to see which works faster or better. It may help us improve orthodontic treatment for people who need their upper canines pulled back.
DhakaAges 18–25 - NCT07814716Recruiting
Dental bands for treating soft enamel in children's back teeth
This study tests whether special metal bands around children's back teeth help protect teeth with soft, weak enamel (from a condition called hypomineralization) and improve the success of fillings. It compares this approach to standard dental care to see which works better.
Natal, Rio Grande do NorteAges 5–10 - NCT07790315Recruiting
Clear aligner comfort study for mild to moderate crowding
This study tests two types of clear aligners to see which one feels more comfortable and works better for patients with mild to moderate crowding. It may help decide which aligner material is better for future patients.
Lahore, Punjab ProvinceAges 15–30 - NCT07747350Recruiting
Laser vs pain pills for braces pain in Malay women
This study compares a low-level laser treatment with standard painkillers to see which works better for reducing pain from getting braces. It is for Malay women aged 18-33 who have never had braces and are generally healthy.
Kota Bharu, KOTA BHARUAges 18–33 - NCT06634017RecruitingPhase 1/Phase 2
Platelet-rich fibrin gel to speed up tooth movement with braces
This study tests whether a special gel made from your own blood (platelet-rich fibrin) can speed up tooth movement after a premolar extraction. You would be wearing braces, and one side of your mouth gets the gel while the other side is the control, so we can see if it works.
Karachi, SindhAges 18–45 - NCT07661277Enrolling by invitation
Success rate of cheekbone mini-screws for braces
This study tests how well tiny screws placed in your upper cheek area work to support braces and move teeth into the right position. It is for adults aged 19 to 35 who need fixed braces on their upper teeth and have not had braces before.
DhakaAges 19–35 - NCT07533240Recruiting
Tooth Wear Treatment Effects on Bite and Jaw
This study looks at how a specific tooth-restoration treatment (called the One-Step No-Prep protocol) affects your bite alignment and jaw joint over time. Researchers want to understand if this treatment helps improve how your teeth fit together.
LiègeAges 18 years+ - NCT07521267Recruiting
Nano-coated screws for teeth straightening in teens
This trial tests special small screws coated with nano-material to help move upper front teeth back into place during braces treatment. The screws act as anchors to make tooth movement more effective for patients with protruding upper front teeth.
Cairo, Cairo GovernorateAges 14–20 - NCT07445555Recruiting
Gum Recession Study: Braces vs. No Braces
This study looks at gum recession (when gums pull away from teeth) in adults, comparing those who had braces in the past to those who did not. It aims to understand if orthodontic treatment affects gum health.
LeuvenAges 18 years+ - NCT07325643Recruiting
Toothpaste and mouthwash to prevent white spots during braces
This study tests if a special toothpaste and mouthwash can stop white spots from forming on teeth while you have braces. It is for people starting orthodontic treatment who have healthy teeth and gums.
BaghdadAges Any age - NCT07288853Recruiting
Can a smartphone app help teens with braces keep cleaner teeth?
This trial tests whether a smartphone app with reminders can help teenagers with braces keep their teeth and gums cleaner. If you're getting braces and have a smartphone, you might be eligible.
Kuantan, PahangAges 12–18 - NCT07280455Recruiting
Comparing gold vs. steel retainers after braces
This study compares two types of fixed retainers (gold vs. stainless steel) to see which works better after braces are removed. It's for people aged 15–30 who have completed orthodontic treatment and have a well-aligned lower front teeth.
Baghdad, Baghdad GovernorateAges 15–30 - NCT06068270Recruiting
MOPs cleaning aid for gum disease patients getting braces
This trial tests whether a special type of oral hygiene device (called MOPs) helps protect teeth and gums during orthodontic treatment (braces or aligners) in people with severe gum disease (stage IV periodontitis). It may help prevent further damage and improve the success of moving teeth.
Madrid, MadridAges 18–80 - NCT07244991Recruiting
Effect of a special toothpaste on plaque bacteria and cavities during braces treatment
This trial tests whether a special paste (MI Paste Plus) can reduce cavity-causing bacteria and prevent early white spots on teeth while you are wearing braces.
Tirana, AlbaniaAges 5–45 - NCT07239024Enrolling by invitationPhase 1
Comparing two ways to speed up canine tooth movement
This study compares two methods to speed up moving your canine teeth into their correct position after removing the premolars: a small surgical procedure (piezocision) or a natural blood concentrate treatment (injectable platelet-rich fibrin). The goal is to see which method works better for faster, safer tooth movement.
CairoAges 14–22 - NCT07217756Recruiting
How weight affects braces treatment in teens
This study looks at how having a higher BMI (body mass index) affects treatment with braces during the teenage years. It will compare results between teens with normal weight and those who are overweight to see if there are any differences in how long or how well braces work.
Rochester, New YorkAges 12–18
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Common questions
- Are there clinical trials for orthodontics?
- Yes. Clin2 currently lists 81 recruiting orthodontics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a orthodontics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a orthodontics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.