Clinical trials
Orthopedics clinical trials
Below are recruiting orthopedics clinical trials, each written for real people, not researchers. We’re tracking 116 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06379919Recruiting
Wound cleaning study for shoulder replacement surgery
This study compares different ways of cleaning the wound during shoulder replacement surgery to see which is more effective at preventing infection. It may help you if you are planning to have a total shoulder replacement.
Orange, CaliforniaAges 18 years+ - NCT06341920Recruiting
BoneFit: exercise before hip or knee replacement
This trial tests a pre-surgery exercise program called BoneFit for people waiting at least 6 months for a hip or knee replacement. The goal is to see if getting stronger before surgery helps recovery.
HullAges 18–75 - NCT07813832Recruiting
Recovery study after knee or hip replacement
This study looks at why some people have problems after knee or hip replacement surgery. It follows patients for three years to understand complications and improve care.
MoscowAges 45 years+ - NCT07739264Recruiting
Robotic hand training for arm weakness
This study tests a robotic hand training system called ZEPU-SG1PLUS to help improve arm and hand function in people with various conditions like stroke or injury. It aims to see if this device can help you move better and do daily activities more easily.
DhakaAges 18–60 - NCT07723742Recruiting
Nutrition education before knee or shoulder surgery
This trial tests whether learning about nutrition before your knee or shoulder arthroscopy helps you recover better after surgery. You'll receive educational materials to help you eat well during your recovery.
Birmingham, AlabamaAges 10 years+ - NCT07714811Recruiting
Hyaluronic acid vs PRP for chronic tendon pain
This study compares two treatments—hyaluronic acid (a natural lubricant) and platelet-rich plasma (PRP, made from your own blood)—for chronic tendon pain. You may be a good fit if you have had pain in your Achilles tendon or golfer's elbow for more than 3 months and are looking for a non-surgical option.
Lublin, Lublin VoivodeshipAges 18–65 - NCT07699601RecruitingPhase 2/Phase 3
Testing a pain tablet after orthopedic surgery
This trial tests an investigational tablet called HL-1186 for controlling pain after orthopedic surgery. It explores whether the drug can safely reduce moderate to severe pain when given after the procedure.
Changsha, HunanAges 18–75 - NCT05760339Recruiting
Intermittent fasting vs carbohydrate drinks before elective surgery
This study compares two ways of eating before planned (elective) orthopedic surgery: intermittent fasting versus carbohydrate drinks. It aims to see which approach is safer and works better around the time of surgery.
Amsterdam, North HollandAges 18 years+ - NCT07687966RecruitingPhase 2
Study of CBP-0276 for pain after major orthopedic surgery
This trial tests if a new medicine, CBP-0276, can help reduce the amount of opioids needed for pain after major bone surgery. It may help manage pain with fewer side effects.
Mexico CityAges 40–75 - NCT06365710Recruiting
Physiotherapy vs telerehab after wrist fracture surgery
This study compares in-person physiotherapy with remote telerehabilitation after a specific type of wrist fracture surgery. It aims to see if doing rehab at home works as well as going to a clinic.
Helsinki, UusimaaAges 18–65 - NCT07665424Recruiting
Study of a bone filling device for spine fractures
This trial tests a device called Vessel-X to treat broken vertebrae (spine bones) caused by osteoporosis or injury. It aims to see if the device is safe and helps stabilize the spine.
TaipeiAges 40–95 - NCT07657039Recruiting
Comparing climate impact of common orthopedic surgeries
This study looks at how much different hand and foot surgeries affect the environment. If you are having one of these procedures at Danderyd's Hospital, you may be able to help researchers learn which methods have a smaller climate footprint.
StockholmAges 18 years+ - NCT05502380RecruitingPhase 3
Antibiotic prevention study for high-risk bone and spine surgeries
This Phase 3 study tests whether giving a broad set of preventive antibiotics before certain high-risk orthopedic surgeries lowers the chance of serious wound or bone infection. It mainly targets people who have contaminated wounds, tumor-related surgery, or known high-risk germs on the skin.
ZurichAges 18 years+ - NCT07562412Recruiting
Audio Mindfulness for Quick Pain Relief
This study tests whether listening to brief guided mindfulness audio recordings can help reduce acute (sudden, short-term) pain. Researchers will see how different amounts of listening affect pain levels.
Tallahassee, FloridaAges 18 years+ - NCT07557550Recruiting
Relaxation methods before orthopedic surgery: glasses vs. virtual reality
This study tests whether watching relaxing videos through special glasses or a virtual reality headset helps reduce anxiety before orthopedic surgery (like hip or knee replacement). Researchers want to see if these tools work better than no relaxation aid at all.
Amiens, PicardieAges 18 years+ - NCT07515092Enrolling by invitation
Virtual Reality Training for Hip Socket Screw Placement
This study tests whether practicing hip socket screw placement in virtual reality helps orthopedic residents learn the procedure better. You would use a VR simulator to practice before doing the actual surgery with supervision.
Bangkok, BangkokAges Any age - NCT07502885Recruiting
Study of walking in children with bone or soft tissue tumors
This study looks at how children with certain bone or soft tissue tumors walk after orthopedic surgery. It aims to understand and improve their movement and recovery.
Memphis, TennesseeAges 5–20 - NCT05831345RecruitingPhase 3
Methadone during surgery to prevent post-surgery pain
This Phase 3 trial tests whether giving methadone during hip or knee replacement surgery can reduce pain after surgery. It may help some people use less rescue pain medicine afterward, but it also has safety checks for kidney, liver, heart, and opioid-related risks.
BrusselsAges 18–80 - NCT07432009Recruiting
Hip replacement and confusion risk in older adults
This study looks at whether older adults who get a hip replacement may experience confusion after surgery. It aims to find factors that might help prevent or reduce this confusion.
BrnoAges 65 years+ - NCT06818552Recruiting
Vascular surgeon's role in orthopedic tumor surgery
This trial is looking at how a vascular surgeon can help during surgery for tumors that involve blood vessels. It may help people with bone or soft tissue tumors that are close to or wrapped around major blood vessels.
Bologna, ItaliaAges 18 years+ - NCT06819436RecruitingPhase 4
Dexamethasone for spinal anesthesia side effects
This trial tests if a steroid called dexamethasone can prevent low blood pressure after spinal anesthesia for orthopedic surgery. If you are having hip, knee, or other bone surgery with spinal anesthesia and are otherwise healthy, this study may help reduce side effects.
Karachi, SindhAges 65–85 - NCT07401095Recruiting
BioBrace for Arthroscopic Ankle Ligament Repair
This trial is for people who need a first-time arthroscopic Brostrom repair to fix a loose ankle ligament. It uses a special material called BioBrace to help the repair heal better.
Greenfield, IndianaAges 18 years+ - NCT06320041RecruitingPhase 4
Oliceridine for pain after orthopedic surgery
This trial tests a new painkiller called oliceridine for moderate to severe pain after orthopedic surgery. It may help you recover more comfortably with fewer side effects.
Yiwu, ZhejiangAges 18–100 - NCT07392099Recruiting
Comparing a single pain relief class vs. usual care after orthopedic surgery
This study tests whether a single, 1-hour class on pain management (called Empowered Relief) can help people recover better after orthopedic surgery (like hip or knee replacement) compared to usual care. It is for people who have had moderate to severe pain for at least 3 months and are fluent in French.
Sherbrooke, QuebecAges 18 years+
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Common questions
- Are there clinical trials for orthopedics?
- Yes. Clin2 currently lists 116 recruiting orthopedics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a orthopedics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a orthopedics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.