Clinical trials
Orthopedics clinical trials
Below are recruiting orthopedics clinical trials, each written for real people, not researchers. We’re tracking 121 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06506968Recruiting
Ergonomics study for heart lab staff
This study looks at how ergonomics (the way your body moves and feels at work) affect staff in the heart catheterization lab. You might join if you work there and are willing to wear special sensors to track your movements.
Boston, MassachusettsAges 21 years+ - NCT07186426RecruitingPhase 3
Testing HSK21542 for pain after hip replacement surgery
This trial tests a new pain medicine called HSK21542 for people who have hip replacement surgery under general anesthesia. It aims to see if the drug can safely reduce moderate to severe pain after surgery.
Beijing, Beijing MunicipalityAges 18–74 - NCT07687966RecruitingPhase 2
Study of CBP-0276 for pain after major orthopedic surgery
This trial tests if a new medicine, CBP-0276, can help reduce the amount of opioids needed for pain after major bone surgery. It may help manage pain with fewer side effects.
Mexico CityAges 40–75 - NCT05831345RecruitingPhase 3
Methadone during surgery to prevent post-surgery pain
This Phase 3 trial tests whether giving methadone during hip or knee replacement surgery can reduce pain after surgery. It may help some people use less rescue pain medicine afterward, but it also has safety checks for kidney, liver, heart, and opioid-related risks.
BrusselsAges 18–80 - NCT07078201RecruitingPhase 4
Comparing two pain meds in spinal anesthesia for leg surgery
This study compares two medicines (dexmedetomidine and fentanyl) added to a spinal numbing shot for people having planned leg or knee surgery. The goal is to see which one works better to keep your blood pressure stable, and to make the numbing last while keeping you comfortable.
Port SaidAges 20–60 - NCT05757739Recruiting
Open debridement versus Tenex for tennis elbow
This trial compares two ways to treat chronic tennis elbow (lateral epicondylitis). It’s meant to see which option works better for long-lasting pain that affects daily activities.
Burlington, New JerseyAges 18–70 - NCT06746168Recruiting
Better pain control after knee replacement surgery
This study tests a new way to manage pain after total knee replacement. It aims to see if a specific local pain block can reduce the need for strong opioids and improve recovery.
Hasselt, LimburgAges 18–85 - NCT07515092Enrolling by invitation
Virtual Reality Training for Hip Socket Screw Placement
This study tests whether practicing hip socket screw placement in virtual reality helps orthopedic residents learn the procedure better. You would use a VR simulator to practice before doing the actual surgery with supervision.
Bangkok, BangkokAges Any age - NCT05677152RecruitingPhase 2
Anti-bone-drug test to help shoulder tendon healing after surgery
This Phase 2 trial studies whether an anti-osteoporosis medicine (zoledronic acid) can improve healing after surgery for a chronic rotator cuff tear in the shoulder. If you qualify, you would also follow a specific 4-week physical therapy plan using a shoulder support pad.
ViennaAges 50–70 - NCT07356323Recruiting
Study on antibacterial drape for hip or knee replacement
This trial tests if a special antibacterial drape reduces contamination during hip or knee replacement surgery. The drape is placed over the skin to help prevent infection.
Fishers, IndianaAges 22 years+ - NCT06973642Recruiting
Home-based rehab after ACL surgery via phone
This trial tests whether a home-based rehab program using your phone can help people recover after anterior cruciate ligament (ACL) reconstruction. It aims to see if remote physical therapy is as effective as in-person sessions.
Jackson, MississippiAges 18 years+ - NCT06107959Recruiting
Metabolism changes after bone or joint surgery
This study measures how your metabolism (how fast your body burns energy) changes after orthopedic surgery (surgery on bones or joints). It may help doctors understand how to better support recovery.
Kansas City, KansasAges 15 years+ - NCT06423300Recruiting
Testing a new implant for kneecap cartilage damage
This trial tests a new implant called the Patellar LIFT System to treat pain caused by cartilage damage behind the kneecap. It is for people who have tried other treatments like physical therapy but still have significant knee pain.
La Mesa, CaliforniaAges 22–65 - NCT06819436RecruitingPhase 4
Dexamethasone for spinal anesthesia side effects
This trial tests if a steroid called dexamethasone can prevent low blood pressure after spinal anesthesia for orthopedic surgery. If you are having hip, knee, or other bone surgery with spinal anesthesia and are otherwise healthy, this study may help reduce side effects.
Karachi, SindhAges 65–85 - NCT07138066Recruiting
Smart crutch tips for guided weight-bearing after tibia fracture
This trial tests a smart crutch tip that helps guide how much weight you put on your leg while recovering from a broken shin bone. It is for people who have had surgery to fix the fracture and are learning to walk again with crutches.
Kyiv, Kyiv OblastAges 18–80 - NCT05943197Recruiting
Microbiology-focused choice of joint prosthetic material
This trial focuses on using lab testing (microbiology) to help choose the best material for a prosthetic used in orthopedic treatment. If you need a prosthetic, this could help doctors select a material more tailored to your situation.
SamaraAges 1 month–1 month - NCT06604364Recruiting
Virtual reality to reduce anxiety before children's arm or leg surgery
This study tests whether watching a virtual reality video can help calm children aged 7 to 12 before minor orthopedic surgery. If your child is having a short procedure (less than an hour) with a numbing shot instead of full sleep medicine, this might be a good fit.
BolognaAges 7–12 - NCT06379919Recruiting
Wound cleaning study for shoulder replacement surgery
This study compares different ways of cleaning the wound during shoulder replacement surgery to see which is more effective at preventing infection. It may help you if you are planning to have a total shoulder replacement.
Orange, CaliforniaAges 18 years+ - NCT06322654Recruiting
Comparing two types of robotic rehab for spinal muscular atrophy
This study compares two robot-assisted rehabilitation programs to see which one helps children and young adults with spinal muscular atrophy (SMA) improve their movement and function better. You may join if you have SMA (types 1-4), are up to 21 years old, and are already receiving medication for SMA.
PoznanAges Up to 21 years - NCT06114043Recruiting
Surgery vs. non-surgery for mild to moderate bunion pain
This trial compares two approaches for treating mild-to-moderate bunion pain: surgery versus non-surgical options like wearing wider shoes, toe spacers, or physical therapy. The goal is to see which works better for relieving pain and improving daily life.
SarpsborgAges 18–80 - NCT07139938Recruiting
Spinal decompression without implants for lumbar stenosis
This trial tests whether removing pressure on spinal nerves alone, without any hardware, can help fix spine balance and reduce pain in people with lumbar stenosis. It is for those who have had leg pain or trouble walking for at least 3 months and plan to have surgery without implants.
MoscowAges 18 years+ - NCT07557550Recruiting
Relaxation methods before orthopedic surgery: glasses vs. virtual reality
This study tests whether watching relaxing videos through special glasses or a virtual reality headset helps reduce anxiety before orthopedic surgery (like hip or knee replacement). Researchers want to see if these tools work better than no relaxation aid at all.
Amiens, PicardieAges 18 years+ - NCT07342647Recruiting
Safer antibiotics for people with beta-lactam allergies in joint replacement surgery
This trial tests a better way to choose antibiotics during joint replacement surgery for patients who are allergic to beta-lactams (a common class of antibiotics). The goal is to prevent infections while avoiding allergic reactions.
StrasbourgAges 18 years+ - NCT07290504Recruiting
Tourniquet Release Methods for People with High Blood Pressure
This study tests two ways of releasing a tourniquet (a pressure cuff) after arm surgery to see which keeps blood pressure more stable in people with controlled high blood pressure. If you are having arm or hand surgery with a tourniquet, you may be able to join.
CairoAges 18–65
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Common questions
- Are there clinical trials for orthopedics?
- Yes. Clin2 currently lists 121 recruiting orthopedics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a orthopedics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a orthopedics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.