Clinical trials
Orthopedics clinical trials
Below are recruiting orthopedics clinical trials, each written for real people, not researchers. We’re tracking 121 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07714811Recruiting
Hyaluronic acid vs PRP for chronic tendon pain
This study compares two treatments—hyaluronic acid (a natural lubricant) and platelet-rich plasma (PRP, made from your own blood)—for chronic tendon pain. You may be a good fit if you have had pain in your Achilles tendon or golfer's elbow for more than 3 months and are looking for a non-surgical option.
Lublin, Lublin VoivodeshipAges 18–65 - NCT04109638Recruiting
PEMF therapy to reduce pain after shoulder or knee surgery
This trial studies whether PEMF, a type of non-surgical device that uses pulsed electromagnetic fields, can reduce pain after shoulder or knee surgery. If you join, you’ll also be expected to do post-surgery physical therapy exercises and report your pain and function.
Redwood City, CaliforniaAges 18 years+ - NCT04140344Recruiting
Study texting messages after low back fusion surgery
This study tests whether regular text-message check-ins after lumbar (low back) fusion surgery are helpful for communication and follow-up. It enrolls people who will be getting their first low back fusion and who are comfortable texting and willing to stay in regular contact.
Durham, North CarolinaAges 18 years+ - NCT04244942Recruiting
CERAMENT bone filler registry for people having bone surgery
This registry study collects information about people who receive CERAMENT™ as part of their bone surgery. It helps doctors understand how the device is used in real-world care and may improve future treatment planning.
Scottsdale, ArizonaAges 18 years+ - NCT04441567Recruiting
Personalized follow-up visits for specific injuries using an app
This study tests whether using the Memora platform to tailor clinic visit timing improves care after certain injuries. You may get more or fewer check-ins based on your recovery information entered on your phone.
Boston, MassachusettsAges 18 years+ - NCT04811313Recruiting
Tranexamic acid for children having hip bone surgery
This study tests whether tranexamic acid (a medicine that helps reduce bleeding) can safely help children during certain hip bone operations. It may help lower blood loss around the surgery.
AsyutAges 1–18 - NCT04811209Recruiting
Testing better pain control and recovery after orthopedic surgery
This trial looks at how well a pain-control plan works after certain orthopedic surgeries and how it affects recovery and patient-reported outcomes. It may help determine what level of pain relief is meaningful to patients after surgery.
Toronto, OntarioAges 18–80 - NCT07699601RecruitingPhase 2/Phase 3
Testing a pain tablet after orthopedic surgery
This trial tests an investigational tablet called HL-1186 for controlling pain after orthopedic surgery. It explores whether the drug can safely reduce moderate to severe pain when given after the procedure.
Changsha, HunanAges 18–75 - NCT07562412Recruiting
Audio Mindfulness for Quick Pain Relief
This study tests whether listening to brief guided mindfulness audio recordings can help reduce acute (sudden, short-term) pain. Researchers will see how different amounts of listening affect pain levels.
Tallahassee, FloridaAges 18 years+ - NCT05073263Recruiting
Full versus partial weight bearing after FCL ligament repair
This study compares two rehab plans: doing full weight bearing versus partial weight bearing during the first 6 weeks after fibular collateral ligament (FCL) reconstruction. It may help figure out which approach is safer and better for healing and recovery.
Edina, MinnesotaAges 14–59 - NCT05073276Recruiting
Controlled weight-bearing after PCL or MCL knee ligament repair
This trial tests a specific, step-by-step approach to how much weight you put on your healing knee after surgery for certain ligament injuries (like PCL and/or MCL, and some combined cases). It may help you heal safely and recover function without putting too much strain on the repair.
Edina, MinnesotaAges 14–59 - NCT05216679Recruiting
Stretching device versus night splints for plantar fasciitis
This trial compares a new at-home stretching device to standard night splints for plantar fasciitis (heel pain from inflammation). It may help find which approach works better and is easier or safer to use.
Carterville, IllinoisAges 18 years+ - NCT05361980Recruiting
Study of safety and results of a pediatric bone implant
This study looks at whether a specific pediatric bone implant is safe and works well for children who need it. By joining, you help researchers track outcomes over time and understand possible implant-related side effects.
Vancouver, British ColumbiaAges birth–25 years - NCT05381818Recruiting
Breathing muscle training before joint surgery
This trial tests whether strengthening breathing muscles before total joint surgery can lower the chance of lung complications after the operation. It may help people who already have breathing problems or a history of smoking.
Jacksonville, FloridaAges 18–100 - NCT05461326Recruiting
Compare two tendon grafts for ACL surgery recovery
This study compares two ways to rebuild the ACL using different tendon grafts (quadriceps tendon vs patellar tendon) taken from your own body. It aims to learn which option leads to better recovery after ACL reconstruction, including strength and function.
Birmingham, AlabamaAges 14–65 - NCT05502380RecruitingPhase 3
Antibiotic prevention study for high-risk bone and spine surgeries
This Phase 3 study tests whether giving a broad set of preventive antibiotics before certain high-risk orthopedic surgeries lowers the chance of serious wound or bone infection. It mainly targets people who have contaminated wounds, tumor-related surgery, or known high-risk germs on the skin.
ZurichAges 18 years+ - NCT05534724Recruiting
Compare early vs partial weight bearing after bunion surgery
This study compares whether it’s safer to put weight on your foot early versus only partly after bunion surgery. It may help your care team choose the best recovery plan for healing and comfort.
LuganoAges 18–85 - NCT05643079Recruiting
Bone screw and tendon transfer for heel bone realignment
This trial studies a specific surgical technique for people who need heel bone realignment along with a tendon transfer. It tests whether using a human donor bone screw helps the bone heal and the tendon work after surgery.
ViennaAges 18 years+ - NCT05760339Recruiting
Intermittent fasting vs carbohydrate drinks before elective surgery
This study compares two ways of eating before planned (elective) orthopedic surgery: intermittent fasting versus carbohydrate drinks. It aims to see which approach is safer and works better around the time of surgery.
Amsterdam, North HollandAges 18 years+ - NCT05899153Recruiting
Gait training with feedback for children with cerebral palsy
This trial tests whether walking practice with real-time feedback (“biofeedback”) can improve how people with cerebral palsy move their legs. It’s designed to help with safer, more efficient walking during treadmill training.
Saint Paul, MinnesotaAges 7–18 - NCT05989230Recruiting
Emotional awareness therapy for pain after orthopedic injury
This trial tests a therapy that helps people understand and express their emotions to manage long-term pain after a serious bone injury. It may help if you have had pain most days for at least three months following surgery for an orthopedic injury.
Baltimore, MarylandAges 18 years+ - NCT06002009Recruiting
Rotator cuff tear study: nerve function and tear size
This study looks at how the size and type of a rotator cuff tear affects the nerve that controls shoulder movement. It may help doctors understand why some tears lead to more pain or weakness.
Stoke-on-TrentAges 18 years+ - NCT06142669Recruiting
Knee revision study using EVOLUTION parts
This study checks how well a specific knee replacement system works in people who need a revision knee surgery (replacing a previous implant). If you have had or will have this surgery with the EVOLUTION parts, researchers will follow you for 10 years to see how the implant performs.
Milan, Piazza C. Ferrari 1 20122 MilanAges 21 years+ - NCT06153121Recruiting
Arm and shoulder tests for healthy tennis players and swimmers
This study is for healthy tennis players and swimmers. It tests a set of physical performance tests for the upper body (arms, shoulders, hands) to see how well they measure athletic ability. If you are a competitive tennis player or swimmer and have no arm or shoulder problems, you may be eligible.
GhentAges 12–40
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Common questions
- Are there clinical trials for orthopedics?
- Yes. Clin2 currently lists 121 recruiting orthopedics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a orthopedics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a orthopedics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.