Clinical trials
Orthopedics clinical trials
Below are recruiting orthopedics clinical trials, each written for real people, not researchers. We’re tracking 117 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06707363Recruiting
Psychological factors and pain after orthopedic surgery
This study looks at how your thoughts and feelings affect your pain after orthopedic surgery. Researchers want to understand these factors to improve care for future patients.
Krakow, MalopolskaAges 18–65 - NCT07846878Recruiting
Predicting pain after orthopedic surgery
This study tests a tool that doctors can use before surgery to predict whether you might have longer-lasting pain after bone or joint surgery. Knowing this in advance could help your care team plan better pain relief for you.
ChongqingAges 18–90 - NCT02355301Recruiting
Improve care for people with orthopedic (muscle or bone) problems
This trial aims to improve the quality of care for people with orthopedic problems, such as issues affecting muscles, bones, or joints. It may help by testing a way of delivering care more effectively.
BrusselsAges 1–90 - NCT07706244Recruiting
Does reducing pre-surgery anxiety help orthopedic patients recover better?
This study tests if a program to reduce anxiety before surgery (Enhanced Recovery After Surgery) improves how patients feel one year after major orthopedic surgery like knee, hip, or spine procedures, compared to standard care.
Hualien City, Hualien CountyAges 20–100 - NCT07662408RecruitingPhase 4
Comparing two drugs to prevent low blood pressure during hip surgery
This trial tests two different medicines (norepinephrine and phenylephrine) given as an infusion to prevent low blood pressure after spinal anesthesia for hip surgery. It may help older adults undergoing planned hip replacement or repair.
SohagAges 60–100 - NCT06713044Recruiting
Quran recitation or music for pain after leg surgery
This trial tests whether listening to Quranic recitation or classical music can reduce pain and inflammation after lower-leg orthopedic surgery. It may help Muslim patients manage pain without extra medication.
Purwokerto, Central JavaAges 18–60 - NCT07522736Recruiting
Spinal anesthesia with dexmedetomidine for knee surgery
This trial tests adding dexmedetomidine (a calming medication) to bupivacaine (numbing medication) injected into the spine during knee surgery. The goal is to improve pain relief and recovery after surgery.
CairoAges 18–65 - NCT06853756Recruiting
Comparing two airway devices in children having orthopedic surgery
This trial compares two types of breathing tubes (I-gel and Ambu AuraGain) used during anesthesia to see which one causes less air to enter the stomach. It is for children ages 2-12 having planned orthopedic surgery.
Tanta, El-GharbiaAges 2–12 - NCT07336277RecruitingPhase 3
Sleep quality study for hospitalized orthopedic trauma patients
This study tests if a special sleep program can help people with leg or foot injuries sleep better in the hospital. It may show if treatments like zolpidem or melatonin help improve sleep after surgery.
Atlanta, GeorgiaAges 18–65 - NCT07339475Recruiting
Using vein size to predict blood pressure drops in older adults during hip or leg surgery
This study uses an ultrasound to measure the size of a vein in your leg before surgery to see if it can predict a drop in blood pressure during the procedure. If you are over 60 and having planned lower-limb surgery with spinal anesthesia, this non-invasive test might help your doctors prepare for your care.
CairoAges 60 years+ - NCT07147543RecruitingPhase 4
Study of a powered exercise device for walking problems
This trial tests if a motorized leg exercise machine can help improve walking and balance in adults with gait disorders. It may be suitable for people who have difficulty walking but can stand with or without help.
Yongin-si, Gyeonggi-do, South KoreaAges 19 years+ - NCT07147491RecruitingPhase 4
Study of a powered exercise device after hip surgery
This study tests a powered exercise device to help people walk better after hip surgery. It's for adults who are medically stable and can sit and stand with support.
Yongin-si, Gyeonggi-do, South KoreaAges 19 years+ - NCT07147530RecruitingPhase 4
Powered exercise device for walking in hip disease
This study tests a new powered exercise device designed to help people with hip problems walk better. It may be a good option if you have hip osteoarthritis or avascular necrosis and can do some standing and walking with support.
Yongin-si, Gyeonggi-do, South KoreaAges 19 years+ - NCT07113483RecruitingPhase 3
Remimazolam vs. Midazolam for sedation in older adults having orthopedic surgery
This trial compares two sedatives, remimazolam and midazolam, to see which one leads to better recovery of thinking skills after orthopedic surgery. It is for people aged 65 and older who are having surgery on a bone or joint while awake but relaxed.
BucharestAges 65 years+ - NCT07013695Recruiting
Virtual reality to reduce sedation in orthopedic surgery
This trial tests if watching virtual reality during regional anesthesia for planned arm or leg surgery can lower the need for calming medicine. It may help you feel more relaxed without as many drugs.
ÉvreuxAges 18 years+ - NCT06995690Recruiting
Ketamine to prevent low blood pressure during orthopedic surgery
This study tests if a low dose of ketamine (a pain medicine) given before spinal anesthesia can prevent dangerously low blood pressure during orthopedic surgery. It might help keep your blood pressure steady, making the procedure safer.
CairoAges 18 years+ - NCT06903819RecruitingPhase 4
Ketamine for pain and mental health after orthopedic injury
This trial tests if ketamine can reduce pain, opioid use, and improve mental health in adults recovering from serious orthopedic injuries. It may help those with high injury severity scores.
Lubbock, TexasAges 18–65 - NCT06627699Recruiting
Study of the Freedom Total Knee System for knee replacement
This study is for people getting a total knee replacement for the first time. It looks at how well the Freedom Total Knee System works in everyday life.
Leawood, KansasAges 18 years+ - NCT03661645Enrolling by invitationPhase 4
Steroid dose taper after orthopedic surgery
This trial tests whether a planned, gradually stopping steroid medicine (methylprednisolone) after certain orthopedic surgeries helps with recovery or symptoms. It compares a post-surgery steroid taper to other routine care and focuses on safety and outcomes after surgery.
Atlanta, GeorgiaAges 18–95 - NCT01840930Recruiting
Study of severe cerebral palsy in children
This study looks at children ages 2 to 10 who have severe, long-term cerebral palsy to better understand this condition. It may help clinicians learn what to expect and how to support children with the most significant mobility needs.
BronAges 2–10 - NCT07872683Recruiting
Drinking carbohydrates before hip or leg surgery: maltodextrin vs sugar water
This study compares two drinks given before surgery—maltodextrin (a carbohydrate powder mixed with water) versus sugar water—to see which one keeps the stomach empty and reduces risks during surgery on the lower limbs. It may help older patients have a safer and more comfortable experience.
Denpasar, BaliAges 60 years+ - NCT06142669Recruiting
Knee revision study using EVOLUTION parts
This study checks how well a specific knee replacement system works in people who need a revision knee surgery (replacing a previous implant). If you have had or will have this surgery with the EVOLUTION parts, researchers will follow you for 10 years to see how the implant performs.
Milan, Piazza C. Ferrari 1 20122 MilanAges 21 years+ - NCT05677152RecruitingPhase 2
Anti-bone-drug test to help shoulder tendon healing after surgery
This Phase 2 trial studies whether an anti-osteoporosis medicine (zoledronic acid) can improve healing after surgery for a chronic rotator cuff tear in the shoulder. If you qualify, you would also follow a specific 4-week physical therapy plan using a shoulder support pad.
ViennaAges 50–70 - NCT06322654Recruiting
Comparing two types of robotic rehab for spinal muscular atrophy
This study compares two robot-assisted rehabilitation programs to see which one helps children and young adults with spinal muscular atrophy (SMA) improve their movement and function better. You may join if you have SMA (types 1-4), are up to 21 years old, and are already receiving medication for SMA.
PoznanAges Up to 21 years
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Common questions
- Are there clinical trials for orthopedics?
- Yes. Clin2 currently lists 117 recruiting orthopedics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a orthopedics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a orthopedics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.