Clinical trials
Osteoarthritis Knees Both clinical trials
Below are recruiting osteoarthritis knees both clinical trials, each written for real people, not researchers. We’re tracking 390 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06809998RecruitingPhase 1/Phase 2
Steroid injection in non-surgical knee before knee replacement
This study tests whether a single steroid injection in the healthy knee (the one not being replaced) can reduce pain and improve recovery after total knee replacement. It may help people who have arthritis in both knees but are only having one replaced now.
Toronto, OntarioAges 18 years+ - NCT06779071Enrolling by invitationPhase 3
NPNP-001 injection for knee osteoarthritis pain
This study tests a new medicine called NPNP-001 for people with knee osteoarthritis who have not gotten enough relief from other treatments. The medicine is given as an injection into the knee to see if it can reduce pain and improve function.
SeoulAges 40 years+ - NCT06781463Recruiting
Knee arthritis treatment registry
This study tracks patients with knee arthritis who undergo a procedure called genicular artery embolization (GAE), a minimally invasive option for those not ready for or not eligible for knee replacement. The goal is to see how well GAE works for pain relief.
Chicago, IllinoisAges 18 years+ - NCT06744036Recruiting
Exercise and electrical stimulation for knee arthritis
This study tests whether adding a gentle electrical current (interferential therapy) to a personalized exercise program can reduce pain and improve function in people with knee osteoarthritis. If you have knee pain from arthritis and have not had physical therapy or certain injections in the past six months, you may be able to join.
São PauloAges 40–75 - NCT05700682Recruiting
MRI-guided artery blockage procedure for long-term joint pain
This study tests whether an MRI scan that looks at blood flow can help target a joint embolization procedure to reduce chronic shoulder, hip, or knee pain. It first uses MRI to find signs of increased blood flow, then may use the findings to guide treatment if you qualify.
Palo Alto, CaliforniaAges 25–80 - NCT06617975Recruiting
Spa therapy for knee arthritis
This trial tests whether spa therapy (balneotherapy) can help people with knee osteoarthritis. You would receive treatment at the Santenay spa as part of your regular care.
Santenay, BurgundyAges 50–80 - NCT06704893RecruitingPhase 3
Amniotic fluid injection for knee arthritis pain
This study tests if an injection made from amniotic fluid can reduce knee pain and improve function in people with moderate knee osteoarthritis. The goal is to give a long-lasting alternative to steroid or gel shots.
Kaohsiung, TaiwanAges 18–80 - NCT06690710RecruitingPhase 1
Gene therapy injection for knee osteoarthritis
This trial tests a new gene therapy injection for knee osteoarthritis. It aims to see if the treatment is safe and if it can help with knee pain and joint function in people with moderate knee osteoarthritis.
OxfordAges 40 years+ - NCT06600958Recruiting
Study of knee arthritis severity and progression
This study looks at how knee osteoarthritis or other types of knee arthritis progress over time, using blood tests and X-rays. It aims to find markers that could predict whether the disease will get worse, which may help guide treatment decisions.
CréteilAges 18 years+ - NCT06574191Recruiting
Knee osteoarthritis study: pain and health outcomes
This study looks at how knee pain from osteoarthritis affects your daily life and health. You'll use a topical anti-inflammatory gel and answer questions by text or email for two months.
Sacramento, CaliforniaAges 50 years+ - NCT06580561Recruiting
Exercise and insomnia treatment for knee pain
This study combines a gentle exercise program with a treatment for insomnia to see if it helps older adults with knee osteoarthritis feel less pain and sleep better. You will attend group exercise classes and receive sleep coaching.
Ann Arbor, MichiganAges 50 years+ - NCT06430918Enrolling by invitation
Nerve pain and sleep quality in knee osteoarthritis
This study looks at how nerve pain and sleep quality are related in people with knee osteoarthritis. It aims to help doctors better understand and treat pain.
IzmirAges 18–80 - NCT06414473RecruitingPhase 1/Phase 2
CBD for knee osteoarthritis pain
This study tests whether a CBD (cannabidiol) product can help reduce pain and improve daily life for people with knee osteoarthritis. If you have moderate to severe knee pain and haven't used cannabis recently, you may be able to join.
Gainesville, FloridaAges 40–75 - NCT06384898Recruiting
Remote tai chi for knee osteoarthritis
This study tests whether doing tai chi remotely, twice a week for 12 weeks, helps reduce knee pain and improve function compared to routine care. Tai chi is a gentle exercise that may ease arthritis symptoms and can be done from home.
Boston, MassachusettsAges 50–100 - NCT06251167Recruiting
Shoe insoles for knee osteoarthritis
This study tests whether shoe insoles can help people with knee osteoarthritis. You might be eligible if you have had knee pain for at least 6 months, your pain is at least moderate, and you also have pain in the same foot.
Vancouver, British ColumbiaAges 50 years+ - NCT06245109RecruitingPhase 4
Pain medicine study for knee osteoarthritis
This study tests how well different pain medicines work for knee osteoarthritis and looks at brain patterns to understand why some people get more relief. It may help you find a treatment that works best for you.
Chicago, IllinoisAges 41 years+ - NCT06208631Recruiting
Movement retraining for knee osteoarthritis pain
This study tests a movement retraining program to see if changing how you walk can reduce stress on your knee and ease osteoarthritis pain. It’s a good fit for people with mild knee pain who want a non-surgical option.
Stanford, CaliforniaAges 18 years+ - NCT06211387Enrolling by invitation
Stretching plus resistance exercise for knee osteoarthritis
This study tests whether adding a gentle stretching technique to resistance exercises helps reduce knee pain and improve movement in people with knee osteoarthritis. It may be a good option if you have mild-to-moderate knee arthritis and want to strengthen your knees without surgery.
Islamabad, FederalAges 40–65 - NCT06228573Recruiting
Brain stimulation and yoga for knee pain
This study combines a gentle brain stimulation technique (tDCS) with yoga to see if it helps reduce knee pain and improve movement in people with knee osteoarthritis.
Hamilton, OntarioAges 45 years+ - NCT06040957Recruiting
Bone marrow vs fat cells for knee osteoarthritis treatment
This trial compares using cells from your bone marrow or belly fat to treat knee osteoarthritis, aiming to reduce pain and improve function. It's for people who haven't gotten better with standard treatments like physical therapy or medications.
BolognaAges 40–75 - NCT05848622Recruiting
Gait retraining after ACL surgery for fast knee recovery
This trial tests a walking (gait) rehabilitation program to improve how you move after ACL reconstruction. It may help if you are still having walking mechanics issues in the months to years after surgery.
Chapel Hill, North CarolinaAges 16–35 - NCT05039463Recruiting
Platelet-Rich Plasma and Hyaluronic Acid for Knee Arthritis
This trial tests whether combining two types of injections—platelet-rich plasma (a concentration of healing cells from your own blood) and hyaluronic acid (a natural lubricant)—can reduce knee osteoarthritis pain and improve function over one year. You're eligible if you've already received or are about to receive these injections at Amiens University Hospital.
AmiensAges 18 years+ - NCT04992624RecruitingPhase 2
Cannabinoid treatment effects on knee pain and nerve signals
This Phase 2 study tests whether a cannabinoid-related treatment changes how pain works in people with knee osteoarthritis. It uses questionnaires, MRI, and gentle nerve testing to understand if treatment helps pain and pain-related signals.
Ann Arbor, MichiganAges 21–75 - NCT04998188Recruiting
Hydrolyzed collagen for one knee with osteoarthritis
This trial tests whether a hydrolyzed collagen drink or supplement can reduce knee pain and symptoms compared with a placebo (inactive treatment) in people with osteoarthritis. It may help if you’ve tried standard non-surgical treatments and still have ongoing knee trouble.
BolognaAges 18–75
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Common questions
- Are there clinical trials for osteoarthritis knees both?
- Yes. Clin2 currently lists 390 recruiting osteoarthritis knees both studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a osteoarthritis knees both trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a osteoarthritis knees both trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.