Clinical trials
Osteoarthritis Knees Both clinical trials
Below are recruiting osteoarthritis knees both clinical trials, each written for real people, not researchers. We’re tracking 390 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04651673Enrolling by invitation
Knee brace program for adults with knee osteoarthritis pain
This trial looks at using a prescribed knee brace to help relieve knee pain and symptoms from knee osteoarthritis. You may be able to join if your knee braces are being provided through participating clinics and you can consent and complete study questionnaires.
Hässleholm, Skåne CountyAges 18–100 - NCT03711773Recruiting
Low-impact exercise classes for joint pain
This study tests a gentle, low-impact exercise program to improve pain and function for adults with knee, ankle, and/or hip pain. You’ll also attend dietitian and behavioral health classes as part of standard care while you participate.
Columbia, MissouriAges 18 years+ - NCT05933434RecruitingPhase 1/Phase 2
Stem cell injection trial for chronic knee osteoarthritis
This early-phase study tests an injection of donor stem cells placed into the knee joint to help reduce symptoms of knee osteoarthritis. You may be eligible if you have long-lasting knee pain from mild-to-moderate arthritis and meet safety and imaging requirements.
Aarhus NAges 40–75 - NCT05120492Recruiting
Program for severe knee arthritis and extreme weight
This feasibility study tests a practical approach to help people with very severe knee arthritis and very high body weight. It aims to find an effective and safe way to manage both conditions together in real-world care.
Halifax, Nova ScotiaAges 18–65 - NCT07767812Recruiting
Motivational interviewing for knee osteoarthritis pain
This study tests whether talking with a counselor (motivational interviewing) helps people with knee osteoarthritis feel more confident in managing their pain and become more physically active. It may help you feel better and move more easily.
Afyonkarahisar, TürkiyeAges 40 years+ - NCT07734311RecruitingPhase 3
Testing a weight-loss injection for knee arthritis pain
This study tests whether an experimental weight-loss injection can reduce knee pain in people who are obese and have knee osteoarthritis. It may help if you have been unable to lose weight through diet and exercise and have moderate knee pain.
Wuhan, HubeiAges 18–75 - NCT06658327Recruiting
Stretching for knee arthritis in postmenopausal women
This study compares two types of stretching to see which better reduces pain and improves movement in postmenopausal women with knee osteoarthritis. It may help you find a simple, drug-free way to manage your symptoms.
Lahore, Punjab ProvinceAges 50–65 - NCT02915120Recruiting
Ultrasound-guided nerve treatment for knee osteoarthritis pain
This trial studies whether a targeted, ultrasound-guided “pulsed” radiofrequency treatment can reduce long-lasting knee pain from osteoarthritis. It may help if your knee pain is not improving with common medicines and injections.
Palma, Balear IslandsAges 40 years+ - NCT05423587Recruiting
Knee artery procedure for long-lasting knee arthritis pain
This study looks at whether blocking small blood vessels in the knee (genicular artery embolisation) can reduce pain from knee osteoarthritis when other non-surgical treatments haven't helped. It also checks safety and whether people can tolerate the imaging tests needed for the procedure.
ReadingAges 45 years+ - NCT07580716RecruitingPhase 2
Knee Injection Treatment for Moderate Osteoarthritis
This study tests a new cell-based injection (Allocetra) directly into the knee joint for people with moderate osteoarthritis who haven't benefited from other treatments. The goal is to reduce pain and improve knee function.
Longwood, FloridaAges 64 years+ - NCT07542808RecruitingPhase 2/Phase 3
Stem cell treatment vs. hyaluronic acid for knee arthritis
This study tests whether an injection of stem cells (special cells that can help repair tissue) works better than a standard hyaluronic acid injection for knee osteoarthritis pain. Both treatments are injected into the knee to reduce pain and improve function.
Abu DhabiAges 18 years+ - NCT06773676Recruiting
Home laser device study for knee osteoarthritis relief
This study tests whether using a laser device at home can help reduce knee pain and improve function in people with knee osteoarthritis. You would use the device yourself over several weeks to see if it eases your symptoms.
Ashkelon, Southern DistrictAges 50–90 - NCT07439575Recruiting
Wound closure methods in hip and knee replacement
This study compares different ways of closing the wound after hip or knee replacement surgery. It looks at which methods heal best with fewer problems.
Istanbul, IstanbulAges 30 years+ - NCT07402447Recruiting
Leg strengthening for knee osteoarthritis and walking
This study tests if strengthening your thigh and calf muscles can improve walking in people with knee osteoarthritis. It may help you walk better and feel more stable.
Peshawar, Khyber PakhtunkhwaAges 40–60 - NCT07226258RecruitingPhase 3
Testing SL1002 for knee pain caused by osteoarthritis
This trial tests a study drug called SL1002 to see if it reduces knee pain from osteoarthritis. It may be an option for people with chronic knee pain who haven't found enough relief from current treatments.
Roseville, CaliforniaAges 40 years+ - NCT06916676Recruiting
Laser therapy for knee osteoarthritis pain
This study tests a type of laser treatment called HILT to see if it can help reduce knee pain from osteoarthritis. You would attend 3 sessions each week for 4 weeks.
CairoAges 18–65 - NCT07178951Recruiting
Ultrasound-guided nerve treatment for knee osteoarthritis pain
This trial tests a non-surgical treatment that uses ultrasound to target nerves causing pain on the inner side of your knee due to osteoarthritis. It may help reduce pain and improve function for people with moderate to severe knee pain.
North York, OntarioAges 18 years+ - NCT06054633Recruiting
L-arginine for knee osteoarthritis pain
This study tests whether L-arginine, a natural amino acid, can help with knee pain from osteoarthritis. You might be eligible if you are 40–80 years old, have moderate osteoarthritis on X-ray, and have had knee pain for at least 3 months.
Changsha, HunanAges 40–80 - NCT06755697Recruiting
Comparing injection methods for knee osteoarthritis
This trial compares two ways to give dextrose injections for knee osteoarthritis: one into the joint space and one guided by MRI into the tissues around the knee. It aims to see which approach works better for pain and function.
TaipeiAges 45–80 - NCT05488093Recruiting
Testing knee movement in severe knee arthritis before replacement surgery
This study checks how well your knee moves and how that relates to pain and function in people with severe knee arthritis who are about to get total knee replacement. It may help doctors better plan and evaluate treatment before surgery.
MontpellierAges 60 years+ - NCT04960098Recruiting
Survey after hip or knee replacement surgery
This study asks people who have had a hip or knee replacement to share how they’re doing over time. It’s testing whether patient-reported survey answers can help measure recovery and outcomes.
MilanAges 18 years+ - NCT06249958Recruiting
Personalized rehabilitation after hip or knee replacement
This study looks at how personalized rehabilitation after hip or knee replacement surgery can improve your quality of life. It is for people who had their surgery at IRCCS Galeazzi Orthopedic Institute in 2019.
Milan, ItaliaAges 18 years+ - NCT06497140RecruitingPhase 3
Genicular artery embolization for painful knee osteoarthritis
This trial tests a new procedure called genicular artery embolization to treat knee pain from osteoarthritis. If you have moderate to severe knee pain and are not a candidate for knee replacement or other surgery, this treatment may help reduce pain and improve function.
ParisAges 40–90 - NCT07580222Recruiting
Using Mobile Technology to Track Knee Arthritis Health
This study uses smartphone or tablet technology to measure how your knee osteoarthritis (wear-and-tear arthritis) changes over time. You'll be helping researchers understand how well a previous arthritis treatment works by tracking your knee health at home.
Palo Alto, CaliforniaAges 30 years+
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Common questions
- Are there clinical trials for osteoarthritis knees both?
- Yes. Clin2 currently lists 390 recruiting osteoarthritis knees both studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a osteoarthritis knees both trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a osteoarthritis knees both trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.