Clinical trials
Osteoarthritis Knees Both clinical trials
Below are recruiting osteoarthritis knees both clinical trials, each written for real people, not researchers. We’re tracking 390 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06726629Recruiting
Italian Knee Questionnaire Study
This study is testing a new Italian version of a questionnaire that measures how your knee feels and works after knee replacement. The goal is to make sure the questionnaire is accurate for Italian-speaking patients.
BolognaAges 18–85 - NCT07351981Enrolling by invitation
Cooled radiofrequency for knee osteoarthritis pain
This study tests a new approach called cooled radiofrequency (TcPRF) to calm knee pain from osteoarthritis. It may be an option if standard treatments haven't worked and you haven't had certain other treatments recently.
AthensAges 45 years+ - NCT07338266RecruitingPhase 1
Study of AVD275 injection for knee osteoarthritis
This trial tests a new injection called AVD275 for people with knee osteoarthritis. It aims to see if the injection is safe and how it works in the body.
Wahroonga, New South WalesAges 20–75 - NCT06549686RecruitingPhase 3
Knee osteoarthritis treatment study with cell therapy
This trial tests a new cell-based treatment (CLS2901C) for knee osteoarthritis. It combines the treatment with a realignment surgery (proximal tibial osteotomy) to help repair cartilage damage and reduce pain.
Ebina, KanagawaAges 20–79 - NCT06592248Recruiting
New ceramic knee replacement for active adults under 70
This trial is testing a new type of knee replacement that uses a ceramic surface to help the knee feel more natural. It may be a good option if you are under 70, have stubborn knee pain from arthritis, and your knee is not too bent out of shape.
ParisAges 18–70 - NCT07473232Recruiting
Comparing platelet-rich plasma and cytokine-rich serum injections for knee osteoarthritis
This trial compares two types of injections (PRP and ACS) to see which one works better for knee osteoarthritis. It may help people with knee pain who have not had these injections recently.
Pamukkale, DenizliAges 40–80 - NCT07219771RecruitingPhase 3
Knee injection for osteoarthritis pain
This study tests a single injection of PTP-001 (MOTYS™) into the knee to see if it reduces osteoarthritis pain. It is for people whose knee pain is their main pain problem and who haven't found relief from standard pain medicines.
Birmingham, AlabamaAges 40–80 - NCT07869680Recruiting
Comparing knee function in people with similar knee arthritis pain
This study looks at how knee osteoarthritis (a common condition where the cushioning in the knee joint wears down) affects physical function, even when people report similar levels of pain. It aims to understand why some people with the same pain might have more difficulty with daily activities, which could lead to better targeted treatments.
MardinAges 40–75 - NCT06483269Recruiting
Platelet-rich plasma injection for knee arthritis in young athletes
This trial tests using your own platelet-rich plasma (PRP), made from a blood sample, as an injection to treat knee osteoarthritis in active young adults. The goal is to see if it reduces pain and helps you stay active.
BolognaAges 18–40 - NCT04472702Recruiting
Ultrasound vs X-ray guidance for knee pain ablation
This trial compares two ways (ultrasound or X-ray guidance) to place a treatment for painful knee arthritis. It aims to see whether one guidance method works as well as the other for reducing knee pain.
Sacramento, CaliforniaAges 35–99 - NCT06082531Recruiting
Platelet-rich plasma injection for knee osteoarthritis
This study tests whether injecting platelet-rich plasma (PRP) from your own blood can help knee pain caused by osteoarthritis or injuries to the cartilage and meniscus. It may be an option if you are between 20 and 60 years old and have not had recent steroid shots or certain health problems.
Xi'an, ShannxiAges 20–60 - NCT07838012Recruiting
Early home cycling after knee replacement surgery
This study tests whether starting gentle cycling at home soon after knee replacement surgery is safe and helpful. It aims to see if patients can use a stationary bike to speed up recovery.
Silkeborg, Central JutlandAges 18 years+ - NCT04137835Recruiting
Noninvasive motion testing for arm and leg function
This study tests how well your upper and lower body moves using non-invasive methods (no procedures or surgery). It’s likely best for healthy adults who can follow instructions and want to help researchers measure movement and function.
Aurora, ColoradoAges 18–65 - NCT06477965Recruiting
Registry for artery embolization to treat chronic pain
This is a registry study that gathers information from people who have had an artery embolization procedure to treat long-term pain from conditions such as arthritis. The goal is to track outcomes and better understand the procedure's effectiveness.
Cary, North CarolinaAges 18 years+ - NCT07464080Recruiting
Brain imaging study for knee replacement patients
This study uses advanced brain scans to understand how pain and recovery change after knee replacement surgery. It may help researchers develop better ways to manage pain after surgery.
Ottawa, OntarioAges 18 years+ - NCT06239649Recruiting
Nerve block before knee replacement for faster recovery
This trial tests whether a numbing injection (nerve block) around the knee before surgery can help you recover faster and feel less pain after a total knee replacement. It is for people with knee osteoarthritis who are ready for their first knee replacement surgery.
Denizli, PamukkaleAges 40–85 - NCT06611618Recruiting
Predicting fall risk in knee osteoarthritis using muscle tests
This study looks at how loss of muscle strength and control in people with knee osteoarthritis can predict falls. It uses tests and MRI to understand your risk, with the goal of helping prevent future falls.
BolognaAges 65–80 - NCT06617871Recruiting
Comparing two ways to align a new knee replacement
This study compares two different techniques (mechanical alignment vs. kinematic alignment) used during knee replacement surgery with a special knee system. It aims to see which technique leads to better results for patients.
Chicago, IllinoisAges 21–79 - NCT05675618Recruiting
Returning to Golf After Joint Replacement Surgery
This study focuses on helping people get back to golfing after common orthopedic (bone/joint) surgeries like hip or knee or shoulder replacement. You may be asked to complete follow-up questionnaires to track recovery and return-to-golf progress.
New York, New YorkAges 18 years+ - NCT07121556Recruiting
Fat tissue vs fat tissue plus gel for knee osteoarthritis
This trial compares two injections for knee arthritis: one uses your own fat tissue, the other adds a lubricating gel. Researchers want to see if the combination helps pain and function more than fat tissue alone.
BolognaAges 18–75 - NCT07347821Recruiting
Study of osteoarthritis in hip and knee replacement patients
This study looks at why osteoarthritis happens in the hip and knee by studying tissue samples taken during joint replacement surgery. If you are already scheduled for a first-time hip or knee replacement and have osteoarthritis, you may be able to join.
Ostrów Mazowiecka, Masovian VoivodeshipAges 18 years+ - NCT04821154Recruiting
Testing outcomes after revision knee replacement with a Persona system
This study looks at how well a specific revision knee replacement system (the Persona system) works after earlier knee problems or surgeries. You may be eligible if you need a revision knee and can follow follow-up care instructions; the trial also checks for certain infection, bone, and health-safety factors.
Fayetteville, ArkansasAges 18 years+ - NCT07703293Recruiting
Testing nerve branches for chronic knee pain relief
This study tests a procedure targeting specific nerve branches in the thigh to treat long-lasting knee pain from osteoarthritis. It may help people who haven't found relief from standard treatments like pain relievers or physical therapy.
AnkaraAges 45–80 - NCT07556003Recruiting
Physical Therapy After Knee Replacement Surgery
This study tests whether a physical therapy program helps improve walking ability and foot pressure patterns in women who have had knee replacement surgery or have knee problems. The goal is to see if structured rehabilitation helps you walk better and more comfortably.
SakakahAges 40–70
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Common questions
- Are there clinical trials for osteoarthritis knees both?
- Yes. Clin2 currently lists 390 recruiting osteoarthritis knees both studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a osteoarthritis knees both trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a osteoarthritis knees both trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.