Clinical trials
Osteoarthritis clinical trials
Below are recruiting osteoarthritis clinical trials, each written for real people, not researchers. We’re tracking 592 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07520721Recruiting
Shoulder Replacement Materials: Plastic vs Hybrid Implants
This trial compares two types of shoulder replacement implants for people with long-standing shoulder arthritis. It tests whether a hybrid design (combining different materials) works better than a traditional plastic design for pain relief and shoulder function.
Hoofddorp, North HollandAges 18 years+ - NCT07496203Recruiting
BETY program after knee injections for osteoarthritis
This trial tests if a special exercise and education program called BETY helps people with knee osteoarthritis feel better after getting a knee injection. You may qualify if you had a knee injection in the last month and have moderate knee arthritis.
Ankara, SamanpazarıAges 18 years+ - NCT06592248Recruiting
New ceramic knee replacement for active adults under 70
This trial is testing a new type of knee replacement that uses a ceramic surface to help the knee feel more natural. It may be a good option if you are under 70, have stubborn knee pain from arthritis, and your knee is not too bent out of shape.
ParisAges 18–70 - NCT07481461Recruiting
Knee alignment and biology in osteoarthritis
This study looks at how changes in knee alignment affect symptoms and joint biology in people with early knee osteoarthritis. It may help doctors understand how to better treat knee OA.
Leuven, Vlaams-BrabantAges 18 years+ - NCT07482332Recruiting
Core exercises for knee arthritis in women
This study tests if core stability exercises can reduce pain and improve function in women with knee osteoarthritis. It is designed for those who have not had recent physical therapy and can move their knees and hips freely.
SivasAges 45–65 - NCT06075004Recruiting
Hip pain relief study comparing two injection methods
This trial tests two ways to give pain medicine around the hip joint during surgery to see which provides better pain relief. It may help patients experience less pain after hip replacement.
Santiago, Santiago MetropolitanAges 18–80 - NCT07478861Enrolling by invitation
Vibration training for seniors with knee arthritis and obesity
This study tests whether whole-body vibration training can help older adults who have both severe knee arthritis and obesity. It aims to improve strength, mobility, and quality of life.
Banī SuwayfAges 60–75 - NCT07474896Recruiting
Nerve-block techniques for shoulder surgery in older adults
This study tests whether certain nerve-block techniques for shoulder surgery can reduce side effects while still controlling pain. It is for people 65 and older having planned shoulder surgery with regional anesthesia.
PoznanAges 65–100 - NCT07472088Recruiting
Knee pain study using weight-bearing CT scans
This trial uses a special CT scan taken while you stand to see how the shape of your knee joint relates to your knee pain. It may help researchers better understand knee arthritis and front-of-knee pain.
Kansas City, KansasAges 18 years+ - NCT06781554Recruiting
Collagen device for thumb arthritis
This trial tests a new collagen-based medical device injected into the thumb joint to treat thumb base arthritis (rhizarthrosis). It aims to see if it safely reduces pain and improves hand function without surgery.
Milan, MIAges 18–75 - NCT04729686RecruitingPhase 4
Nerve block during hip replacement for less postoperative pain
This trial tests whether a specific nerve block given during planned hip replacement surgery can reduce pain afterward. It may help you use less opioid pain medicine, but you must meet certain safety and medication criteria.
Baltimore, MarylandAges 18–80 - NCT07464080Recruiting
Brain imaging study for knee replacement patients
This study uses advanced brain scans to understand how pain and recovery change after knee replacement surgery. It may help researchers develop better ways to manage pain after surgery.
Ottawa, OntarioAges 18 years+ - NCT07458360Recruiting
Front block for better recovery after hip replacement
This study tests if a special nerve block called the front block (pericapsular nerve group block) improves recovery after hip replacement surgery. You may be eligible if you are having hip replacement under spinal anesthesia and do not have certain health issues.
KonyaAges 18 years+ - NCT06280352Recruiting
Robotic vs custom knee replacement trial
This study compares two modern ways of doing knee replacement: robot-assisted surgery versus a custom-made implant tailored to your knee shape. It aims to see which approach leads to better recovery and function for people with osteoarthritis.
Graz, StyriaAges 40–90 - NCT07449403Recruiting
Pain after hip replacement: testing a nerve block
This study tests a special numbing injection (called a PENG block) given around the hip joint to see how well it controls pain after hip replacement surgery. If you are having a hip replacement under spinal anesthesia and are in generally good health, this study may help find better ways to manage your post-surgery pain.
PoznanAges 65–100 - NCT07449442Recruiting
Pain relief study after knee replacement surgery
This trial tests a special injection around the knee to improve pain control after knee replacement surgery. It may help reduce the need for strong pain medicines.
PoznanAges 65–100 - NCT07449468Recruiting
Nerve block to prevent confusion after hip replacement
This trial tests whether a nerve block (PENG block) can reduce confusion (delirium) after hip replacement surgery in older adults. It is for people 75+ scheduled for a first-time hip replacement under spinal anesthesia.
PoznanAges 75–100 - NCT07442812Recruiting
Dexamethasone: pill vs. IV for knee replacement recovery
This trial compares two ways of giving dexamethasone (a strong anti-inflammatory) for people having knee replacement surgery. One group gets a pill and the other gets an IV. The goal is to see which method works better for pain, swelling, and recovery.
Istanbul, IstanbulAges 50–80 - NCT05806021RecruitingPhase 4
Tested different cortisone doses for knee osteoarthritis pain
This trial compares different doses of injected cortisone (triamcinolone) directly into the knee to see which dose helps knee osteoarthritis pain most. You may be enrolled in a group receiving a 5 mg, 10 mg, or 40 mg dose if you meet the study’s knee and health requirements.
Montreal, QuebecAges 50 years+ - NCT06040827Recruiting
Study of a knee implant extension for knee replacement
This trial is for adults having their first knee replacement surgery. It tests a special part (tibial extension) of a common knee implant system. Researchers will follow participants over time to see how well it works.
Fayetteville, ArkansasAges 18 years+ - NCT07429955Recruiting
Study on muscle and recovery after hip surgery in older adults
This trial looks at how muscle health affects your ability to get back to normal activities after hip replacement surgery for a broken hip or severe arthritis. By using MRI scans and other tests, researchers hope to understand if having less muscle makes recovery harder.
MontpellierAges 75 years+ - NCT07426549Recruiting
Knee Exercises With Blood Flow Restriction for Osteoarthritis
This study compares two types of knee exercises (closed chain and open chain) with a special blood flow restriction technique to see which helps reduce pain and improve function in people with mild to moderate knee osteoarthritis.
RawalpindiAges 45–75 - NCT06701474Recruiting
Knee replacement recovery: comparing body composition groups
This study looks at how well people recover after total knee replacement, comparing those with different body composition levels. The goal is to see if a measure called 'phase angle' affects recovery of strength and function.
Yongin-si, Gyeonggi-doAges 55 years+ - NCT07423858Recruiting
E-coach for hip and knee arthritis advice
This study tests a digital coach that gives you personalized advice to manage your hip or knee arthritis. It aims to help you get the right guidance at the right time.
UtrechtAges 45 years+
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Common questions
- Are there clinical trials for osteoarthritis?
- Yes. Clin2 currently lists 592 recruiting osteoarthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a osteoarthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a osteoarthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.