Clinical trials
Osteoarthritis clinical trials
Below are recruiting osteoarthritis clinical trials, each written for real people, not researchers. We’re tracking 592 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07425457Recruiting
Cold nerve treatment before knee replacement surgery
This trial tests a cold therapy on nerves before knee replacement to reduce pain. It may help you recover with less discomfort after surgery.
AthensAges 18 years+ - NCT06825650Recruiting
Turkish adaptation of a pain questionnaire
This study aims to adapt a questionnaire about pain into Turkish and check if it works well. Researchers want to see if the questions are understandable and reliable for people with certain types of pain.
Ankara, AltındağAges 18 years+ - NCT07397806Recruiting
Home-based leg trainer for knee osteoarthritis
This study tests a home exercise device designed to improve leg control and reduce pain in people with knee osteoarthritis. You may be eligible if you have knee pain and are between 40 and 85 years old.
Vail, ColoradoAges 40–85 - NCT07396233Recruiting
Knee Osteoarthritis Therapy: Diagonal Movement Patterns
This trial tests a type of physical therapy called proprioceptive neuromuscular facilitation for people with knee osteoarthritis. It may help reduce pain and improve how well your knee works.
Karachi, SindhAges 40–60 - NCT07383740Recruiting
Reliability of a gentle bike test for hip or knee osteoarthritis
This study checks whether a simple, low-effort bike test gives consistent results for people with hip or knee osteoarthritis. It helps doctors understand how well this test can measure your fitness without pushing you too hard.
GothenburgAges 30 years+ - NCT07380906Recruiting
Knee artery embolization for knee arthritis registry
This trial is testing a procedure called genicular artery embolization (GAE) to treat knee osteoarthritis. If your knee pain hasn't improved with standard treatments like medicine, this study may be a way to try something new.
Libertyville, IllinoisAges 18 years+ - NCT07386600Recruiting
Comparing two drugs for knee replacement pain relief
This trial tests two different drugs (dexamethasone and dexmedetomidine) added to a standard nerve block for knee replacement. It aims to see which one provides better pain control after surgery.
PoznanAges 65–100 - NCT06129214Recruiting
Partial tendon cleaning to reduce knee clicking after replacement
This trial studies a partial cleaning procedure on the quadriceps tendon during knee replacement to reduce clicking or rubbing sensation (crepitus). It is only for people getting a specific type of knee implant (posterior-stabilized) and whose kneecap is not replaced.
Seoul, GangnamGuAges 19 years+ - NCT07377669Enrolling by invitation
Partial knee replacement plus ACL repair study
This study tests a combination surgery: repairing the torn ACL at the same time as replacing only the damaged part of your knee. It's designed for active people with arthritis in one knee compartment and a fully torn ACL.
BolognaAges 18–75 - NCT07367126Recruiting
Nerve pain in knee osteoarthritis: Pain and function study
This study looks at nerve-related pain in people with knee osteoarthritis and how it affects their pain level and daily function. It may help understand if nerve pain is a key factor in your knee OA symptoms.
IstanbulAges 40–70 - NCT07367789Recruiting
Predicting recovery after knee replacement using smart insoles
This study uses special insoles to measure how you walk before and after a knee replacement. The goal is to see if these measurements can help predict how well you will recover after surgery.
Yongin-si, Gyeonggi-doAges 19 years+ - NCT07361198Recruiting
Knee artery embolization for arthritis pain
This trial tests a minimally invasive procedure to block small blood vessels in the knee, which may reduce pain from osteoarthritis. It's for people with ongoing knee pain even after standard treatments like medication or physical therapy.
Ústí nad LabemAges 40–80 - NCT07360093Recruiting
Nerve block for chronic hip pain from osteoarthritis
This study tests a nerve block treatment for people with long-term hip pain from osteoarthritis who haven't gotten enough relief from other treatments. It aims to see if this procedure can help reduce pain.
AnkaraAges 18–80 - NCT04031820Recruiting
Comparing two hip cup types to prevent dislocation
This trial compares a “dual-mobility” hip cup to a “unipolar” hip cup during primary hip replacement, focusing on dislocation (the hip coming out of place) and overall cost-effectiveness. It may help your care team choose the best implant for you and monitor outcomes after surgery.
AmsterdamAges 70 years+ - NCT04049279Recruiting
Testing hip implant cement amount for better stability
This study compares hip implant “migration” (how the implant may slowly shift) when a cemented hip cup is used with different cement approaches. It may help surgeons choose the option that keeps the implant more stable over time.
AmsterdamAges 65 years+ - NCT06856356Recruiting
Robot-assisted knee replacement surgery study
This study tests if robot-assisted total knee replacement surgery is safe and effective. It may help people who need knee replacement surgery by using advanced technology for more precise implant placement.
Hefei, AnhuiAges 18–80 - NCT07351981Enrolling by invitation
Cooled radiofrequency for knee osteoarthritis pain
This study tests a new approach called cooled radiofrequency (TcPRF) to calm knee pain from osteoarthritis. It may be an option if standard treatments haven't worked and you haven't had certain other treatments recently.
AthensAges 45 years+ - NCT07347028Recruiting
Trigger point injections for knee osteoarthritis pain
This trial tests whether injecting medication into muscle knots (trigger points) can reduce knee pain in people with knee osteoarthritis. It may be an option if other treatments haven't helped enough.
Beijing, Beijing MunicipalityAges 45 years+ - NCT07339111RecruitingPhase 3
CARTISTEM vs surgery for knee cartilage damage and osteoarthritis
This trial tests if a cell-based treatment called CARTISTEM can repair knee cartilage better than surgery alone. It involves people with knee osteoarthritis and a cartilage defect, with moderate pain and limited function.
Birmingham, AlabamaAges 18–75 - NCT07339137Recruiting
PRP injections for chronic knee osteoarthritis
This trial tests if platelet-rich plasma (PRP) injections into and around the knee joint can reduce pain and improve function for people with moderate knee osteoarthritis who haven't gotten relief from other treatments.
Ankara, ÇankayaAges 40–65 - NCT06729983Recruiting
Tendon lengthening during reverse shoulder replacement
This study tests whether slightly lengthening a tendon during reverse shoulder replacement improves outcomes. It's for adults getting their first reverse replacement at Loyola sites.
Maywood, IllinoisAges 18 years+ - NCT07332182Recruiting
MaioRegen scaffold for deep knee cartilage injuries
This study tests a special scaffold (MaioRegen Prime) that helps regrow cartilage and bone in deep knee injuries. It is for people who have not gotten better with physical therapy and need a repair option.
La Mesa, CaliforniaAges 18–60 - NCT07327372Recruiting
Numbing with sedation for hip surgery in older adults
This trial tests a numbing injection (called a PENG block) plus a sedative (dexmedetomidine) for older adults having hip surgery. The goal is to see if this combination gives better pain relief and fewer side effects.
PoznanAges 65–100 - NCT07330999Recruiting
PENG block variants with and without extra medications for older adults undergoing hip surgery
This trial tests three ways of doing a PENG block (a type of pain relief injection for hip surgery) with or without added medications (adjuvants) to see which works best for older adults. It aims to improve pain control and reduce the need for other pain medicines after surgery.
PoznanAges 65–100
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Common questions
- Are there clinical trials for osteoarthritis?
- Yes. Clin2 currently lists 592 recruiting osteoarthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a osteoarthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a osteoarthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.