Clinical trials
Osteoarthritis clinical trials
Below are recruiting osteoarthritis clinical trials, each written for real people, not researchers. We’re tracking 610 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05227924Recruiting
Testing safety and performance of a hip implant device type
This study checks how safe and well a specific brand of hip implant (SYMBOL range) works in people getting a total hip replacement. It may help by confirming the device performs as expected for primary or revision surgeries.
BeaumontAges 18 years+ - NCT05246813Recruiting
Study blood cell changes in older adults
This study looks at how blood-forming stem cells change in people with clonal hematopoiesis (CHIP), a common age-related blood condition. It may help researchers understand what these changes mean and who might be at higher risk for future blood problems.
Bonheiden, BelgiëAges 55 years+ - NCT05292339RecruitingPhase 4
Ketorolac shot for painful hand and arm tendon/joint problems
This trial studies whether a ketorolac injection can safely reduce pain and symptoms from certain shoulder, elbow, hand, or wrist tendon or joint conditions. It may help people who haven’t had surgery for the problem yet.
Atlanta, GeorgiaAges 18 years+ - NCT05302934Recruiting
Testing a knee-surgery app and sensor after knee replacement
This trial checks whether a data platform that uses a wearable sensor and a phone app works well for people getting a total knee replacement. It may help make follow-up care more organized and easier by capturing recovery information.
Konstanz, Baden-WurttembergAges 18 years+ - NCT05357378Recruiting
Hip replacement study using a reverse hip implant
This trial looks at how safe and well a specific “reverse” hip implant works in people who need their first total hip replacement. It may help by improving pain and hip function, while closely tracking safety during and after surgery.
Miami, FloridaAges 50–75 - NCT05407610Recruiting
Compare two types of nerve pain treatments for knee pain
This study compares conventional versus cooled radiofrequency treatments for long-lasting knee pain. It aims to see which method reduces pain better and helps patients function more comfortably.
AntwerpAges 18 years+ - NCT05408065Recruiting
Compare pain relief from two shoulder injections for arthritis
This study compares how well two different shoulder injections reduce pain from moderate-to-severe shoulder osteoarthritis. You would receive injections in only one shoulder and answer questionnaires about pain and function.
Montreal, QuebecAges 20 years+ - NCT05412381RecruitingPhase 3
PRP after ACL injury to help prevent knee arthritis
This study tests whether PRP (platelet-rich plasma) given after an ACL injury and surgery can lower the chance of developing long-term knee arthritis. It may help protect the knee over time by targeting early healing after ACL reconstruction.
New York, New YorkAges 14–50 - NCT05484089Recruiting
CapFlex implant trial for finger joint replacement
This trial studies a new implant (the CapFlex) to replace a damaged finger joint (the PIP joint) when conservative treatments are not enough. It may help reduce pain and improve stability for the right type of joint problem.
Zoetermeer, South HollandAges 18 years+ - NCT05495334Recruiting
Add knee osteoarthritis outcomes to a patient registry
This study tests a new way to collect how people with knee osteoarthritis feel and function after usual care (like injections, nerve-blocking procedures, or knee replacement). It may help improve future treatment decisions by using your regular follow-up reports in an app or online.
Phoenix, ArizonaAges Any age - NCT05501743RecruitingPhase 2
Injection from your own tissue and platelets for wrist arthritis
This Phase 2 trial tests whether an injection made from your own microfat tissue mixed with platelet-rich plasma can reduce pain and improve function in radiocarpal (wrist) osteoarthritis. It compares this approach to a different standard treatment called total wrist denervation.
Marseille, Bouches-du-RhôneAges 18 years+ - NCT05514405Recruiting
Testing two anesthesia medicines to prevent confusion after surgery
This trial tests whether using remimazolam or propofol during hip or knee replacement surgery can lower the risk of postoperative delirium, a sudden, short-term confusion that can happen after anesthesia. It may help people who are at higher risk of postoperative confusion by finding the safer anesthesia approach.
SeoulAges 65–100 - NCT05517434RecruitingPhase 2/Phase 3
Autologous bone and fat injections versus saline for knee OA
This trial compares different knee injections made from your own bone marrow and/or fat, plus platelet-rich plasma (a blood-derived healing factor), against saline (placebo) to treat painful knee osteoarthritis. It aims to see whether these “autologous” injections reduce knee pain and improve function.
Toronto, OntarioAges 30 years+ - NCT05596591Recruiting
Shockwave treatment for knee arthritis pain with MRI-confirmed lesions
This trial tests whether focused shockwave therapy (a non-surgical treatment) can reduce knee arthritis pain. It specifically targets people whose MRI shows a small bone problem in one area of the knee.
Cedar Knolls, New JerseyAges 30–80 - NCT05603728Recruiting
Follow-up study for Exactech shoulder implants after surgery
This study follows people who get (or already had) a shoulder replacement to see how the implant is doing over time. It may help improve future care by tracking long-term performance and safety.
Laguna Woods, CaliforniaAges 21 years+ - NCT05686278Recruiting
Study of long-term outcomes after hip hemiarthroplasty
This is an observational study that follows people over time after hip hemiarthroplasty (a partial hip replacement). It aims to understand how well Corin hip devices work long-term in everyday care, and what outcomes to expect.
Amboise, FranceAges 18 years+ - NCT05719935Recruiting
KinematX wrist replacement registry for people with wrist arthritis
This trial is a registry that follows people who get (or already had) a KinematX total wrist replacement. It collects health and recovery information to better understand outcomes for different wrist problems, like arthritis or certain bone alignment issues.
Loma Linda, CaliforniaAges 18–85 - NCT05732870Recruiting
Study looks for blood and gene signals that affect bone health
This study collects information and samples around the time of certain bone or joint surgeries (like joint replacement or fracture repair) to learn what factors help or harm bone healing. The results may help find better targets to improve long-term bone health and recovery.
London, Greater LondonAges 18–110 - NCT05734651Recruiting
Study of PROMIS stem in hip replacement patients
This study looks at people who had a hip replacement (total hip arthroplasty) using the PROMIS stem. The goal is to evaluate how this specific hip part performs in real-world use.
Sankt Johann in Tirol, TyrolAges 18 years+ - NCT05785884Recruiting
Diet program to help knee osteoarthritis pain
This trial studies whether different diet approaches can reduce knee pain in people with knee osteoarthritis who have certain eating patterns. It may help by changing diet-related factors that can affect inflammation and pain.
Birmingham, AlabamaAges 40–75 - NCT05800457Recruiting
Test synovectomy to reduce pain after knee replacement
This study looks at whether a procedure called synovectomy (removing inflamed joint lining) can reduce pain after a first knee replacement on one side. It focuses on people with clear signs of inflammation on ultrasound and checks follow-up outcomes after surgery.
London, OntarioAges 41–80 - NCT05823727Recruiting
Collagen supplement study before and after knee replacement
This study tests whether taking collagen peptides can improve how knee tissues heal and remodel after total knee arthroplasty (knee replacement). It also looks at functional recovery and wound healing, especially during the physical therapy period in Little Rock.
Little Rock, ArkansasAges 50–75 - NCT05839535RecruitingPhase 2
Baduanjin plus brain stimulation for knee osteoarthritis pain
This Phase 2 study tests whether combining Baduanjin (a guided mind-body movement) with neuromodulation can improve knee osteoarthritis symptoms and function. It compares education-based stretching/control and uses MRI scanning as part of the research.
Charlestown, MassachusettsAges 45–75 - NCT05840887Recruiting
Knee realignment surgery with donor meniscus transplant
This trial studies whether combining knee bone realignment surgery (osteotomy) with a donor meniscus transplant can improve knee pain and function in people with arthritis from uneven leg alignment. You would need to commit to physical therapy and repeat checkups with X-rays and MRI scans.
BolognaAges 20–60
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Common questions
- Are there clinical trials for osteoarthritis?
- Yes. Clin2 currently lists 610 recruiting osteoarthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a osteoarthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a osteoarthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.