Clinical trials
Osteogenesis Imperfecta clinical trials
Below are recruiting osteogenesis imperfecta clinical trials, each written for real people, not researchers. We’re tracking 11 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04115774Recruiting
Registry for people with osteogenesis imperfecta
This study is a registry, meaning it collects health information about people with osteogenesis imperfecta (OI) to better understand the condition. It may help researchers learn what care works best and how OI varies from person to person.
Bologna, Emilia-RomagnaAges Any age - NCT05419960Recruiting
Hearing and balance testing for teens with osteogenesis imperfecta
This study checks how well the inner ear and balance system work in children and young adults with osteogenesis imperfecta (OI). The goal is to better understand hearing and balance issues that can affect daily life.
ParisAges 12–20 - NCT05927389Recruiting
Exercise program for kids with osteogenesis imperfecta
This trial tests an adapted physical activity program to help children and teenagers rebuild strength and improve effort/fitness. It may be helpful if you want a tailored exercise approach that is safe for osteogenesis imperfecta.
MontpellierAges 7–18 - NCT07287241Recruiting
Heart health study for people with osteogenesis imperfecta
This study looks at heart structure and function in children and adults with osteogenesis imperfecta (OI), a condition that affects bones. Researchers want to understand how OI may impact the heart.
Bologna, Emilia-RomagnaAges 5–80 - NCT07366086RecruitingPhase 3
Long-term safety of romosozumab for osteogenesis imperfecta in children
This study follows children who previously received romosozumab in an earlier trial to check their long-term safety. It helps understand if the treatment's benefits last safely over time.
Indianapolis, IndianaAges 5–19 - NCT02432625Recruiting
Long-term study of bone fragility in osteogenesis imperfecta
This study follows people with osteogenesis imperfecta (OI) to better understand how it affects bones and related issues over time. It may help doctors learn which features and genetic changes predict problems, and guide future care.
Phoenix, ArizonaAges Any age - NCT07478224Recruiting
Blood flow restriction training for osteogenesis imperfecta type I
This study tests whether a special type of strength training, called blood flow restriction training, can improve muscle, bone, and quality of life in adults with osteogenesis imperfecta type I.
GhentAges 18–65 - NCT07557446RecruitingPhase 2
Testing AGA2115 for Osteogenesis Imperfecta in Chinese Patients
This study tests a new medicine called AGA2115 in adults and teenagers with osteogenesis imperfecta (brittle bone disease). The trial aims to find the right dose and see if it can strengthen bones and reduce fracture risk.
Beijing, Beijing MunicipalityAges 12–75 - NCT07062588RecruitingPhase 2
AGA2115 for osteogenesis imperfecta in adults with COL1A1/COL1A2 variations
This trial tests a new drug called AGA2115 for people with osteogenesis imperfecta (also known as brittle bone disease) who have a confirmed genetic change in the COL1A1 or COL1A2 genes. The study aims to see if the drug can help strengthen bones and reduce fracture risk.
Phoenix, ArizonaAges 18–75 - NCT04152551RecruitingPhase 4
Bisphosphonate use and hearing loss in type 1 osteogenesis imperfecta
This study looks at whether bisphosphonate treatment affects hearing loss in people with type 1 osteogenesis imperfecta. If you qualify, it may help researchers understand if treatment can protect hearing over time.
New York, New YorkAges 6–100 - NCT07412782Recruiting
REMS bone scan study for children with bone conditions
This study uses a new ultrasound technology called REMS to check bone health in children aged 5 to 18 who have conditions that weaken bones. It may help find low bone density without radiation.
Florence, TuscanyAges 5–18
Hear when a new Osteogenesis Imperfecta trial opens
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Common questions
- Are there clinical trials for osteogenesis imperfecta?
- Yes. Clin2 currently lists 11 recruiting osteogenesis imperfecta studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a osteogenesis imperfecta trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a osteogenesis imperfecta trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.