Clinical trials · California
Overweight or Obesity clinical trials in California
We’re tracking 114 recruiting overweight or obesity studies with a site in California — including Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT06724172Recruiting
Comparing health programs for pregnant mothers from diverse backgrounds
This study tests two different health programs for pregnant women to see which one helps mothers and babies more. You may join if you are early in your pregnancy, identify as Black, Hispanic, or have Medicaid, and speak English or Spanish.
Palo Alto, CaliforniaAges 18 years+ - NCT06824974Recruiting
Time-restricted eating for liver disease or cancer
This study tests whether combining time-restricted eating with healthy eating helps people with metabolic liver disease, cirrhosis, or early-stage liver cancer. If you are overweight and currently fast less than 12 hours at night, this diet approach might improve your health.
La Jolla, CaliforniaAges 18 years+ - NCT06891352Recruiting
Timing meals to reduce disease risk in night shift workers
This study tests whether adjusting when you eat (time-restricted eating) can improve health in night shift workers. You would use a smartphone app to track your meals and follow a set eating schedule for up to a year.
La Jolla, CaliforniaAges 18–70 - NCT06994338RecruitingPhase 2
Tirzepatide for alcohol use disorder
This study tests whether a medication called tirzepatide (a once-weekly injection) can help people reduce their alcohol consumption. It is for people who drink heavily, have a high BMI, and are actively seeking help to drink less.
Los Angeles, CaliforniaAges 21–65 - NCT07013643RecruitingPhase 1
How a new weight-loss drug affects birth control pills
This study checks if a new weight-loss medicine changes how the body handles birth control pills. It is for healthy women with overweight or obesity.
Glendale, CaliforniaAges 35–75 - NCT07044570Recruiting
Examining attitudes in physical activity engagement
This trial tests if a program can help people who are not very active start and stick with a physical activity routine. Participants will wear a study-provided smartwatch to track their activity and answer brief surveys.
Los Angeles, CaliforniaAges 18 years+ - NCT07316816Recruiting
Weight loss study for teens with severe obesity
This study evaluates how continuous glucose monitors and other wearable devices can help teens in a bariatric program lose weight. You may join if you are in the program and ready for sleeve gastrectomy or GLP-1 medication.
Palo Alto, CaliforniaAges 10–18 - NCT07675590RecruitingPhase 1
Safety study of TIX100 in healthy volunteers
This study tests a new oral medication called TIX100 in healthy people to see if it is safe and how the body handles it. It is the first step in human testing, so it focuses on safety and side effects.
Chula Vista, CaliforniaAges 18–70 - NCT07509307RecruitingPhase 3
Study of a new medicine for weight loss and knee pain in osteoarthritis
This trial tests if a new medicine, NNC0487-0111, can help people with excess weight and knee osteoarthritis lose weight and reduce knee pain. It is for people who have had knee pain for at least three months and who can stop taking pain relievers for short periods before study visits.
Escondido, CaliforniaAges 18 years+ - NCT07514260RecruitingPhase 1
Safety study of ABBV-295 injections in Japanese adults with overweight
This is an early-stage safety study testing a new injectable medication (ABBV-295) in healthy Japanese adults who are overweight or have obesity. The study measures how well the body tolerates the drug and how it moves through the body.
Anaheim, CaliforniaAges 18–65 - NCT07533175RecruitingPhase 3
Testing a new weight-loss medicine for type 2 diabetes
This study tests whether a new medicine called NNC0487-0111 helps people with type 2 diabetes and excess weight lose weight. You'll take the medicine along with your current diabetes care to see if it works better than standard treatment.
Escondido, CaliforniaAges 18 years+ - NCT07571005RecruitingPhase 3
Testing a New Weight-Loss Medicine for Sleep Apnea
This study tests whether a new injectable medicine called NNC0487-0111 helps people with excess weight and moderate-to-severe obstructive sleep apnea (a condition where breathing stops repeatedly during sleep) lose weight and improve their sleep apnea—without needing a CPAP machine. The goal is to see if better weight loss can reduce sleep apnea symptoms.
San Diego, CaliforniaAges 18 years+ - NCT07607587RecruitingPhase 1
Testing a new weight-loss drug for people who couldn't tolerate GLP-1 shots
This study tests a new injectable medication called cagrilintide for people with obesity who had to stop GLP-1 drugs (like Ozempic or Wegovy) because of stomach problems. The goal is to see if cagrilintide causes fewer stomach side effects while still helping with weight.
Walnut Creek, CaliforniaAges 18 years+ - NCT05606731Recruiting
Family coaching to help prevent childhood weight gain
This study offers a family-focused program for Latino adult caregivers of young children to help prevent childhood obesity. If your child is already overweight, the program may help you learn practical ways to support healthier habits as a family.
Los Angeles, CaliforniaAges 2 years+ - NCT07291232RecruitingPhase 1
Study of an injected drug for adults with obesity
This study tests an injected medication called ABBV-295 for adults with obesity. The goal is to see how safe it is and how the body processes it. You may join if you have a BMI between 30 and 45 and are generally healthy, and you haven't been on other weight loss treatments recently.
Anaheim, CaliforniaAges 18–65 - NCT06439277RecruitingPhase 3
Tirzepatide for teens with obesity and related health problems
This study tests a medication called tirzepatide (a once-weekly injection) to help teenagers with obesity and related health conditions lose weight. It aims to see if the drug is safe and effective for this age group.
Los Angeles, CaliforniaAges 12–17 - NCT07284979RecruitingPhase 3
Weekly injection for obesity without diabetes
This trial tests a new once-weekly injection called Ribupatide for weight loss in people with obesity who do not have diabetes. It compares the study drug to an existing medication (semaglutide) and a placebo to see how well it works and if it's safe.
Northridge, CaliforniaAges 18 years+ - NCT07567001RecruitingPhase 3
Testing NNC0487-0111 for Heart Failure and Obesity
This study tests whether a new medication called NNC0487-0111 can help people with heart failure who also have obesity. Researchers will compare it to a placebo (inactive pill) to see if it improves heart function and overall health.
Alhambra, CaliforniaAges 18 years+ - NCT03022682Recruiting
Study of inflammation and metabolism across diabetes and weight
This is an observational study that follows generally healthy adults to understand how inflammation, diabetes (type 2), and weight/metabolic health relate to each other. It may help researchers figure out why different groups (including different ethnic backgrounds) have different health risks.
San Francisco, CaliforniaAges 18–75 - NCT04721873RecruitingPhase 2
Weight-loss medicine for people with ulcerative colitis
This study tests whether a weight-loss medication, along with usual ulcerative colitis care, can help people who have both ulcerative colitis and obesity. It focuses on people with active symptoms or who need ongoing steroid medicine, and it also checks safety with heart, blood, infection, and mental-health screenings.
La Jolla, CaliforniaAges 18–80 - NCT05143697Recruiting
Coaching program to help young children reduce excess weight
This trial tests a family wellness coaching program using motivational interview counseling and referrals. It may help families support healthier habits for children ages 2 to 8 who have weight above a recommended range.
Pasadena, CaliforniaAges 2–8 - NCT05165706Recruiting
Study of how obesity affects insulin resistance over time
This study follows adults over time to understand how weight and body chemistry relate to insulin resistance. It may help researchers learn why insulin resistance happens and what could prevent or improve it.
Stanford, CaliforniaAges 35–65 - NCT05419726Recruiting
Semaglutide study to see how brown fat responds in weight loss
This trial studies how brown fat (a type of body fat) changes after starting semaglutide for weight loss. You may help researchers understand how this medication affects the body’s energy use, which could improve weight-loss treatments.
Los Angeles, CaliforniaAges 18 years+ - NCT05740254Recruiting
Compare early versus late eating times for teen obesity
This study tests whether having a shorter daily eating schedule earlier in the day works better than a later eating schedule for reducing weight and improving health in teens with obesity. Participants will also follow planned fasting (not eating) periods and complete regular check-ins.
Los Angeles, CaliforniaAges 12–21
Overweight or Obesity trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting overweight or obesity studies listed above.
- University of California San Diego Health · 3 studies
- CenExel ACT (Anaheim Clinical Trials) · 2 studies
- Children's Hospital Los Angeles · 2 studies
- Desert Oasis Healthcare Medical Group · 2 studies
- Diablo Clinical Research · 2 studies
- Stanford University · 2 studies
- Altman Clinical and Translational Research Institute
- Amicis Research Center
What taking part in a overweight or obesity study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Overweight or Obesity trials in other states
Common questions
- Are there overweight or obesity clinical trials in California?
- Yes. We're currently tracking 114 recruiting overweight or obesity studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a overweight or obesity study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New overweight or obesity studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.