Clinical trials · San Diego, CA
Overweight or Obesity clinical trials in San Diego
We’re tracking 41 recruiting overweight or obesity studies with a site in or near San Diego — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near San Diego
- NCT06783751Recruiting
New surgical method to reduce acid reflux after weight loss surgery
This trial tests a modified version of sleeve gastrectomy that aims to reduce the risk of acid reflux (GERD) after surgery. It is for people aged 18–65 with a BMI between 35 and 55 who already have some degree of GERD and are planning to have weight loss surgery.
San Diego, CaliforniaAges 18–65 - NCT05726942Recruiting
Using a weight-management mobile app for adults with extra weight
This trial studies whether a mobile phone app can help people manage weight. It may help you if you have overweight or obesity and are able to track your weight with a bathroom scale.
San Diego, CaliforniaAges 18–64 - NCT06596902Recruiting
Physical activity program for Latino families near the U.S.-Mexico border
This trial tests a program to help Latino families become more active and fit. It takes place at community centers near the border and includes both parents and children.
San Diego, CaliforniaAges 6 years+ - NCT07037433RecruitingPhase 3
Heart protection study for people with heart disease and overweight
This study tests a new weekly injection (maridebart cafraglutide) to see if it helps lower the risk of heart problems in people with heart disease and overweight. It is for adults who have had a heart attack, stroke, or artery blockages and also have a BMI of 27 or higher.
San Diego, CaliforniaAges 45–99 - NCT05589155Recruiting
Using a phone app to improve blood sugar and weight
This study looks at whether a mobile phone app can help people with type 2 diabetes improve their health habits, including blood sugar monitoring and weight. You may be able to join if you already check your blood sugar daily and are able to use a smartphone.
San Diego, CaliforniaAges 18–64 - NCT07446439RecruitingPhase 3
Tradipitant for nausea from weight loss injections
This study tests whether the drug tradipitant can help reduce nausea and vomiting caused by weight loss injections like Ozempic or Wegovy. If you have these side effects and are not diabetic, you may be eligible.
San Diego, CaliforniaAges 18–65 - NCT07571005RecruitingPhase 3
Testing a New Weight-Loss Medicine for Sleep Apnea
This study tests whether a new injectable medicine called NNC0487-0111 helps people with excess weight and moderate-to-severe obstructive sleep apnea (a condition where breathing stops repeatedly during sleep) lose weight and improve their sleep apnea—without needing a CPAP machine. The goal is to see if better weight loss can reduce sleep apnea symptoms.
San Diego, CaliforniaAges 18 years+ - NCT07392190RecruitingPhase 3
Study of eloralintide for people with persistent obesity
This trial tests if adding eloralintide helps people who are still obese or overweight while taking weekly incretin therapy. It aims to support additional weight loss for those who haven't reached their goals.
San Diego, CaliforniaAges 18 years+ - NCT07441252RecruitingPhase 2
Study of maridebart cafraglutide for fatty liver with obesity
This trial tests a new medication (maridebart cafraglutide) to see if it can reduce fat in the liver and help with weight loss. It may be an option for adults with excess liver fat and obesity or overweight who haven't been able to lose weight with diet and exercise alone.
San Diego, CaliforniaAges 18–99 - NCT07654374RecruitingPhase 3
Study of a new pill for weight loss and diabetes
This study tests a new daily pill (aleniglipron) to help adults with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be a good fit if you have a BMI of 27 or higher and your diabetes is managed with A1c between 6.5% and 10%.
San Diego, CaliforniaAges 18–79 - NCT07567001RecruitingPhase 3
Testing NNC0487-0111 for Heart Failure and Obesity
This study tests whether a new medication called NNC0487-0111 can help people with heart failure who also have obesity. Researchers will compare it to a placebo (inactive pill) to see if it improves heart function and overall health.
San Diego, CaliforniaAges 18 years+ - NCT07575932RecruitingPhase 2
Testing New Weight Loss Medications PF-08653945 and PF-08653944
This study tests two new experimental medications designed to help adults lose weight and improve weight-related health conditions like high blood pressure and sleep apnea. Participants will take one of these medications to see if it's safe and effective.
San Diego, CaliforniaAges 18 years+ - NCT07351045RecruitingPhase 3
Study of enicepatide for weight loss in obesity or overweight
This study tests a new injectable medication called enicepatide for people with obesity or overweight who have not been able to lose weight through diet and exercise alone. It may help you lose weight and improve health conditions linked to excess weight.
San Diego, CaliforniaAges 18 years+ - NCT07575399RecruitingPhase 3
Switching to a New Weight-Loss Medication From Current GLP-1
This trial tests whether switching from your current GLP-1 medication (like Ozempic or Wegovy) to a new drug called maridebart cafraglutide works as well or better for weight management. You must have already lost at least 10% of your body weight on your current GLP-1 and be doing well with it.
San Diego, CaliforniaAges 18–99 - NCT07564414RecruitingPhase 3
Weight Loss Study Comparing Two Doses of CagriSema
This study tests whether a new combination medication called CagriSema (in two different doses) helps people with obesity lose weight. You may qualify if you're 18 or older, have a BMI of 35 or higher, and either don't have type 2 diabetes or have it well-controlled.
San Diego, CaliforniaAges 18 years+ - NCT07684235RecruitingPhase 3
Long-term study of a weight-loss drug for trial graduates
This study tests a drug called Maridebart Cafraglutide for long-term weight management in people who completed a previous related trial. It looks at how well the drug works and its safety over time.
San Diego, CaliforniaAges 18–99 - NCT07654361RecruitingPhase 3
A new pill for weight loss in obesity and overweight
This study tests an investigational pill called aleniglipron to see if it helps people with obesity or overweight who also have a weight-related health problem (like high blood pressure) lose weight safely. It is a Phase 3 trial, meaning it is in the final stages before seeking approval.
San Diego, CaliforniaAges 18–79 - NCT05279729Recruiting
Mobile app coaching for people with diabetes
This study tests whether using a smartphone app can help people with type 2 diabetes manage their health. It focuses especially on low-income Hispanic/Latinx adults who regularly check blood sugar.
San Diego, CaliforniaAges 18–64 - NCT06323070Recruiting
Watermelon vs. low-fat cookies for wellness
This trial compares eating watermelon or low-fat cookies to see how they affect your overall wellness. It will help determine if one snack is better for your health.
San Diego, CaliforniaAges 18–50 - NCT06864026RecruitingPhase 4
Adding tirzepatide to ixekizumab for psoriatic arthritis with weight concerns
This study tests adding tirzepatide (a once-weekly injection for weight and diabetes) to your current treatment with ixekizumab for psoriatic arthritis. It may help with both joint symptoms and weight.
San Diego, CaliforniaAges 18 years+ - NCT07037459RecruitingPhase 3
A study of a new drug for heart failure with obesity
This trial tests a medication called maridebart cafraglutide for people with heart failure (where the heart doesn't pump as well as it should) and obesity. The goal is to see if it can help improve symptoms and outcomes.
San Diego, CaliforniaAges 18–99 - NCT07743463RecruitingPhase 3
Daily pill for weight loss in adults with overweight or obesity
This trial tests an investigational once-daily pill (ASC30) to see if it can help adults with overweight or obesity lose weight. You may be able to join if you have a high body mass index (BMI) and have tried to lose weight before.
Chula Vista, CaliforniaAges 18 years+ - NCT07675590RecruitingPhase 1
Safety study of TIX100 in healthy volunteers
This study tests a new oral medication called TIX100 in healthy people to see if it is safe and how the body handles it. It is the first step in human testing, so it focuses on safety and side effects.
Chula Vista, CaliforniaAges 18–70 - NCT07743450RecruitingPhase 3
Once-daily pill for weight loss in people with type 2 diabetes
This study tests an oral medication, ASC30, to see if it helps people with type 2 diabetes who are overweight or obese lose weight and improve blood sugar control. It is a once-daily pill that may offer a new treatment option.
Chula Vista, CaliforniaAges 18 years+
Hear when a new Overweight or Obesity trial opens near San Diego, CA
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Overweight or Obesity trials in other cities
Where these studies are running near San Diego
Institutions with a site for the recruiting overweight or obesity studies listed above.
- San Diego State University · 5 studies
- Artemis Institute for Clinical Research · 4 studies
- Apex Clinical Research · 3 studies
- ACCOMPLISH Research Site · 2 studies
- Research Site · 2 studies
- Scripps Health · 2 studies
- Acclaim Clinical Research
- AURORA-1 Clinical Site
What taking part in a overweight or obesity study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting overweight or obesity studies in California.
Common questions
- Are there overweight or obesity clinical trials near San Diego?
- Yes. We're currently tracking 41 recruiting overweight or obesity studies with a site near San Diego, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a overweight or obesity study near San Diego?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in San Diego to take part?
- Not necessarily. These studies have a site near San Diego, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New overweight or obesity studies open near San Diego regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.