Clinical trials
Overweight or Obesity clinical trials
Below are recruiting overweight or obesity clinical trials, each written for real people, not researchers. We’re tracking 1,534 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06305208Recruiting
UK registry for weight loss endoscopy procedures
This study collects information from patients in the UK who have a weight loss procedure done through an endoscope (a thin tube down the throat). It helps doctors learn more about how well these procedures work and how safe they are.
LondonAges 18–99 - NCT06308757Recruiting
Studying a very low calorie keto diet for fatty liver disease with scarring
This trial tests whether a very low calorie ketogenic diet (a strict low-carb, high-fat diet) can help people with non-alcoholic steatohepatitis (NASH) who have liver scarring. Participants will follow this diet for a year and have two liver biopsies to see if their liver health improves.
BolognaAges 18 years+ - NCT06309563Recruiting
Essential amino acid diet for severe obesity
This study tests whether replacing some foods with essential amino acids (protein building blocks) can improve metabolism in people with severe obesity. It aims to find a non-surgical way to boost weight loss.
Oggebbio, VerbaniaAges 45–65 - NCT06309576Recruiting
Study on body weight regulation using liquid meals
This study tests how the body regulates weight by having participants drink only a special liquid meal for two days. It may help researchers understand weight changes in people with low or high body weight.
Baton Rouge, LouisianaAges 18–40 - NCT06323538Recruiting
Plant-based diets and health (COPLANT)
This study looks at how different plant-based diets affect your health. Researchers will collect information through questionnaires and blood samples to understand the benefits of eating more plants.
ViennaAges 18–69 - NCT06858761Recruiting
Robot-assisted weight loss surgery: cost and results study
This study looks at whether using a robot during weight loss surgery is worth the cost. It compares outcomes for people having their first bariatric surgery or a repeat surgery for complications.
BordeauxAges 18–70 - NCT06329349Recruiting
Metabolic flexibility and lifestyle change study
This study looks at how your body's metabolism responds to lifestyle changes like diet or exercise. If you are an adult with obesity (BMI over 30) and no major health issues, you may be able to join a program that helps you understand your body's energy use.
PragueAges 25–45 - NCT06329544Recruiting
Study of a high-fructose diet and gut health
This trial tests how a high-fructose diet affects your gut bacteria and overall metabolic health. It is for people who already know they don't absorb fructose well (fructose malabsorbers) and want to understand how this sugar impacts their body.
New York, New YorkAges 25–45 - NCT06338631Recruiting
Early kidney check in people with excess weight
This study looks for early signs of kidney problems in people with excess weight, even if they are otherwise healthy. It aims to understand how weight affects kidneys before any disease develops.
MilanAges 18–60 - NCT06341179Recruiting
Does more sleep help children learn and manage weight?
This study tests whether helping children sleep longer each night can help them learn better and manage their weight. It is for children ages 6–12 who are above a healthy weight and sleep 9 hours or less per night.
CopenhagenAges 6–12 - NCT06364644Recruiting
Reducing heart failure risk in low-income adults with diabetes
This study looks at how low income and diabetes together raise the risk of heart failure. It offers a program to help you manage your health and reduce that risk.
Baltimore, MarylandAges 30–70 - NCT06372015Recruiting
Diet program vs bariatric surgery for liver health
This study compares two ways to help people with obesity and liver problems: a special diet program or weight-loss surgery. Researchers will look at changes in fats, immune system, and genetic markers to see which approach works better.
Castellana Grotte, BariAges 18 years+ - NCT06374368Recruiting
Small bowel diversion surgery for obesity
This trial tests a surgery called small bowel diversion to help people with obesity lose weight. It may also improve blood sugar control for those with type 2 diabetes.
OstravaAges 18–65 - NCT06384313Recruiting
Butyrate supplement for preventing diabetes
This study tests if a special type of fat (butyrate) can help prevent diabetes in people who are overweight and have early signs of blood sugar problems. You would take a supplement for several weeks to see if it improves how your body handles sugar.
Maastricht, LimburgAges 20–70 - NCT06390189Recruiting
Inflammation resolution in heart and metabolic health
This study examines how your body naturally resolves inflammation, which is important for heart health and conditions like diabetes. It involves blood draws and tests to understand how inflammation works.
AarhusAges 18–75 - NCT06392854RecruitingEarly Phase 1
Fat tissue and insulin in obesity
This early-phase trial tests how fat tissue in different parts of the body responds to insulin. It may help researchers understand why some people with obesity are more prone to health problems like diabetes or heart disease.
Rochester, MinnesotaAges 18–65 - NCT06396871Recruiting
Blood cell study in metabolic diseases
This study looks at blood cells and factors in people with metabolic diseases like fatty liver, prediabetes, or type 2 diabetes. It aims to better understand these conditions by comparing them with healthy volunteers.
Dresden, SaxonyAges 18 years+ - NCT06408961Recruiting
EVs in Obesity and Cardiometabolic Disease
This study looks at tiny particles released by cells (called extracellular vesicles, or EVs) in people with obesity and related heart health issues. Researchers want to see if these particles are different in people with obesity and diabetes, which could help find new ways to treat or prevent heart problems.
Boston, MassachusettsAges 18 years+ - NCT06409962Recruiting
New school program for childhood obesity and prediabetes
This study tests a new program to help children with obesity, focusing on those with slightly higher blood sugar (prediabetes). It takes place at a school and requires both parent and child consent.
CórdobaAges 6–16 - NCT06414096RecruitingPhase 1
Can a fertility drug help women with obesity get pregnant?
This study tests if a special way of giving a fertility drug (FSH) can improve pregnancy chances in women with obesity who are having trouble conceiving. It aims to understand how the drug affects reproductive health.
Aurora, ColoradoAges 19–37 - NCT06416969RecruitingEarly Phase 1
Study of fat breakdown in overweight adults
This study looks at how fat cells in the belly release fat. Researchers want to learn more about fat breakdown in people who are overweight or obese. If you join, you may get a drug that helps them measure fat activity.
Rochester, MinnesotaAges 18–65 - NCT06420700Recruiting
Stomach Lining Ablation with Sleeve Gastroplasty for Weight Loss
This study combines two endoscopic procedures to help you lose weight: one that reduces the size of your stomach and one that alters the stomach lining. It is designed for people who are ready to commit to long-term diet changes.
Atlanta, GeorgiaAges 18–65 - NCT06425016Recruiting
Robot-assisted vs. traditional sleeve gastrectomy
This study compares two types of weight-loss surgery: one done with the help of a robot and the other done by hand (laparoscopic). Both are types of sleeve gastrectomy, where the stomach is reduced in size. If you qualify for sleeve gastrectomy, this trial may help doctors learn which method works better.
Cleveland, OhioAges 18–70 - NCT06428617Recruiting
Stomach ablation treatment for weight loss
This trial studies a new stomach procedure called fundus ablation to help with weight loss. The doctor uses a device to treat the upper part of your stomach, and you'll follow a special diet long-term.
Cary, North CarolinaAges 18–65
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Common questions
- Are there clinical trials for overweight or obesity?
- Yes. Clin2 currently lists 1,534 recruiting overweight or obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.