Clinical trials · Columbus, OH
Pain clinical trials in Columbus
We’re tracking 27 recruiting pain studies with a site in or near Columbus — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Columbus
- NCT07632820RecruitingPhase 4
Nerve Block vs. Injection for Upper Back Muscle Pain
This study compares two ways to treat chronic muscle pain in the upper back: a nerve block (numbing injection near the spine) and trigger point injections (shots directly into painful muscle knots). The goal is to see which approach works better for long-lasting relief.
Columbus, OhioAges 18–80 - NCT05944354Enrolling by invitation
Wearable system to study spine health for military readiness
This study tests whether a wearable setup can measure spine health during training and daily movement. It may help improve how military members with or without neck or low back pain are monitored and supported.
Columbus, OhioAges 18–64 - NCT06184945Recruiting
Study of ICU staffing and support strategies
This study looks at how different staffing and support strategies may help patients who need a breathing machine in the ICU. Researchers want to see if these approaches can improve care and recovery.
Columbus, OhioAges 19 years+ - NCT02890485Recruiting
Dry needling for knee pain with stair or squat pain
This study tests whether dry needling can reduce ongoing knee pain in people who feel pain around the kneecap when going up or down stairs, squatting, or running. You may be able to join if your knee pain has lasted at least 3 months and you’re referred to physical therapy.
Columbus, OhioAges 18–40 - NCT07228390RecruitingPhase 2
Testing ritlecitinib for hidradenitis suppurativa in adults
This study tests an oral medicine called ritlecitinib for moderate to severe hidradenitis suppurativa (HS) in adults who haven't responded well to antibiotics. The goal is to see if it can reduce painful red lumps and improve quality of life.
Columbus, OhioAges 18–75 - NCT07049029Recruiting
Physical activity and pain resilience study for teens
This study tests if physical activity can help teenagers with chronic pain feel better and be more active. It may help you learn ways to manage pain.
Columbus, OhioAges 12–17 - NCT06223659RecruitingPhase 2
EMLA cream for pain during lymphoscintigraphy for skin cancer
This trial tests whether EMLA cream can reduce pain from injections needed to map lymph nodes for certain skin cancers. If you are scheduled for lymphoscintigraphy and sentinel lymph node biopsy, you may be eligible.
Columbus, OhioAges 18–99 - NCT06795126Enrolling by invitation
Virtual reality for pain and anxiety in kids getting IVs
This study tests if a virtual reality game called Little NIRVANA can help reduce pain and anxiety in children getting an IV. It's for kids ages 2 to 8 in the emergency department.
Columbus, OhioAges 2–8 - NCT05673551Enrolling by invitation
VR during at-home burn dressing changes for kids
This trial tests whether virtual reality (VR) can help children feel better during daily burn dressing changes at home. It will study comfort and pain around the first time you do dressings after leaving the hospital.
Columbus, OhioAges 6–17 - NCT06994442RecruitingPhase 3
Best pain relief for children on a breathing tube
This study tests adding extra pain medicines (acetaminophen or an NSAID) to usual opioid pain treatment for children on a breathing machine. The goal is to find the safest and most effective way to manage pain.
Columbus, OhioAges 2 months–17 years - NCT07778069Enrolling by invitation
Virtual reality for children having joint steroid injections
This study tests whether using virtual reality (VR) during a steroid joint injection helps children feel less pain and anxiety. If it works, it could make the procedure easier for patients from 5 to 17 years old.
Columbus, OhioAges 5–17 - NCT07704554Recruiting
Dural puncture epidural for labor pain relief
This study compares a modified epidural technique (dural puncture epidural) to the standard method for managing labor pain. It aims to see if the new approach is safer or works better for women in labor.
Columbus, OhioAges 18 years+ - NCT05776771Recruiting
Spine movement study for people with back or neck pain
This study measures how your spine and back/neck move using motion testing and equipment. It may help researchers better understand differences between people with spine pain and people without.
Columbus, OhioAges 18 years+ - NCT06854991Enrolling by invitation
Virtual reality for managing pain in healthy kids
This study tests if virtual reality can help distract children and teenagers from the feeling of pain. It could show that VR is a helpful tool for managing pain without medicine.
Columbus, OhioAges 6–17 - NCT07447700Recruiting
Massage therapy during radiation for breast cancer
This study tests if focused chair massages after each radiation treatment can help with pain, movement, and quality of life for breast cancer patients. You would receive massages during your radiation treatment period.
Columbus, OhioAges 18 years+ - NCT06908538Recruiting
Cryo nerve block for pain after amputation
This study is testing a treatment called a cryo nerve block to reduce pain after amputation, including phantom limb pain. It will look at whether freezing the nerve during surgery helps people feel less pain and use less pain medicine.
Columbus, OhioAges 18 years+ - NCT06671002RecruitingPhase 4
Pain medicine safety study for kids having surgery
This study compares different pain medicines to see which works best and is safest for children after surgery for tonsil removal, gallbladder removal, or knee arthroscopy. It aims to help find the most effective and least risky pain control option.
Columbus, OhioAges 12–20 - NCT07016581Enrolling by invitation
Best length for a spinal cord stimulation test
This study is testing how long a spinal cord stimulation trial should last to best diagnose whether it will help your chronic pain. It compares different trial lengths to see which one gives the most accurate result.
Columbus, OhioAges 18 years+ - NCT06054802Enrolling by invitation
Sleep and pain after spine surgery in teens
This study looks at how sleep quality before and after spine surgery affects pain recovery. It uses text messages to check in with participants, so a mobile device is needed.
Columbus, OhioAges 10–18 - NCT07700108RecruitingPhase 2
Pain relief for epidural needle insertion in pregnant women
This study compares two ways to numb the skin before placing an epidural needle: a lidocaine patch placed on the back versus a lidocaine injection under the skin. The goal is to find which method is more comfortable for pregnant women during labor or cesarean delivery.
Columbus, OhioAges 18 years+ - NCT05645224Enrolling by invitation
Virtual reality for pain and anxiety during laser skin treatment
This study tests whether using virtual reality (VR) during a laser procedure for a skin condition helps children and teens feel less pain and anxiety. If you are having your first laser treatment, you might be able to use a VR headset to distract you during the procedure.
Columbus, OhioAges 5–25 - NCT06721819RecruitingPhase 3
Sleep and brain training before heart surgery to prevent delirium
This study tests whether a combination of sleep therapy, brain games, and light exercise before heart surgery can help prevent confusion or disorientation (delirium) after the operation. Participants will be asked to use a tablet and fitness tracker daily for about an hour before their surgery.
Columbus, OhioAges 60 years+ - NCT05986292RecruitingPhase 2
Study of new treatments for chronic pain
This study tests new treatments for chronic pain that lasts at least 3 months. Participants must stop their regular pain medicines and use only a rescue painkiller if needed. The goal is to find better ways to manage long-term pain.
Columbus, OhioAges 18 years+ - NCT01719055Recruiting
Long-term follow-up for Boston Scientific pain nerve stimulation
This study looks at how well a Boston Scientific nerve stimulation device works over the long term for pain in everyday care. You may be able to join if you’re already being set up to use one of these approved systems and can reliably report your pain outcomes.
Columbus, OhioAges 18 years+
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Pain trials in other cities
Where these studies are running near Columbus
Institutions with a site for the recruiting pain studies listed above.
- The Ohio State University Wexner Medical Center · 13 studies
- Nationwide Children's Hospital · 9 studies
- Centricity Research
- ClinOhio Research Services
What taking part in a pain study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting pain studies in Ohio.
Common questions
- Are there pain clinical trials near Columbus?
- Yes. We're currently tracking 27 recruiting pain studies with a site near Columbus, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pain study near Columbus?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Columbus to take part?
- Not necessarily. These studies have a site near Columbus, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pain studies open near Columbus regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.