Clinical trials · San Diego, CA
Pain clinical trials in San Diego
We’re tracking 49 recruiting pain studies with a site in or near San Diego — including Phase 1, Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near San Diego
- NCT06728579RecruitingPhase 2
Group therapy for joint pain in breast cancer survivors
This study tests two supportive group programs—one using mindfulness skills, the other providing supportive talk therapy—to help breast cancer survivors manage joint pain caused by hormone-blocking pills. If you have ongoing joint pain and are taking an aromatase inhibitor, you may be able to join a free, video-based group.
San Diego, CaliforniaAges 18 years+ - NCT04004286Recruiting
Pain registry and blood sample biobank for eligible service members
This trial is building a pain registry biobank to learn more about pain and how different people experience it. If you’re eligible for care in the Military Healthcare System and can consent, you may be able to contribute your information for future research.
San Diego, CaliforniaAges 18–80 - NCT07641517RecruitingPhase 2
Testing LY4065967 for chronic knee osteoarthritis pain
This study tests an experimental drug called LY4065967 to see if it can help reduce pain from osteoarthritis in the knee. You'll be in the trial for several months, with regular check-ins and pain assessments.
San Diego, CaliforniaAges 40 years+ - NCT06665204Recruiting
Knee pain treatment study for active military
This study tests whether following a standard treatment guide helps active-duty service members with kneecap pain feel better. You would receive physical therapy and be monitored for a few weeks.
San Diego, CaliforniaAges 18 years+ - NCT04849455RecruitingPhase 4
Nerve-block catheters plus spinal morphine for liver surgery pain
This trial tests whether placing pain-relief catheters near the back muscle plus giving morphine into the spinal fluid can improve comfort during and after liver surgery. It may help reduce the need for stronger opioid pain medicines afterward.
San Diego, CaliforniaAges 18 years+ - NCT01719055Recruiting
Long-term follow-up for Boston Scientific pain nerve stimulation
This study looks at how well a Boston Scientific nerve stimulation device works over the long term for pain in everyday care. You may be able to join if you’re already being set up to use one of these approved systems and can reliably report your pain outcomes.
San Diego, CaliforniaAges 18 years+ - NCT07285018RecruitingPhase 2
Study of a new drug for diabetic nerve pain in legs
This trial tests an investigational drug for people with pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It may help reduce pain in your lower legs if other treatments haven't worked well.
San Diego, CaliforniaAges 18 years+ - NCT05658575RecruitingPhase 2/Phase 3
Tablets to treat sudden gout flare pain
This trial studies dapansutrile tablets (OLT1177) to see how well they work for people in the first 4 days of an acute gout flare. It may help reduce pain and inflammation in the specific joint where your gout is flaring.
San Diego, CaliforniaAges 18 years+ - NCT05444361Enrolling by invitation
Ultrasound freezing treatment for pain after mastectomy
This trial tests a “freezing” nerve procedure guided by ultrasound to help reduce pain after mastectomy. It aims to lessen postoperative pain by temporarily calming specific nerves involved in chest wall sensation.
San Diego, CaliforniaAges 18 years+ - NCT05963607Recruiting
Weighted blanket trial to reduce chronic pain
This study tests whether using a 15-pound weighted blanket can lower pain and improve sleep for Veterans with long-lasting, non-cancer musculoskeletal pain. It may help by reducing discomfort during rest and sleep.
San Diego, CaliforniaAges 18 years+ - NCT07641504RecruitingPhase 2
Testing LY4065967 for chronic low back pain relief
This study tests whether a new medication called LY4065967 can reduce chronic low back pain. Researchers want to see if it works better than current treatments for people who have had lower back pain for at least 3 months.
San Diego, CaliforniaAges 18 years+ - NCT07325513Recruiting
Brain stimulation for Gulf War-related pain
This study tests whether a type of brain stimulation (repeated transcranial magnetic stimulation, or rTMS) can help reduce headaches and body pain in veterans with Gulf War Illness. If you are a Gulf War veteran with ongoing moderate-to-severe pain, this trial could help find a new way to manage your symptoms.
San Diego, CaliforniaAges 18–65 - NCT05737121RecruitingPhase 2
Study drug for bladder pain compared with lidocaine, heparin, or placebo
This Phase 2 trial tests VNX001 to see if it helps people with interstitial cystitis/bladder pain syndrome (IC/BPS) compared with its separate ingredients (lidocaine and heparin) or a placebo (inactive treatment). You may be eligible if you have had IC/BPS for months and recently had a moderate-to-severe bladder pain flare.
San Diego, CaliforniaAges 18 years+ - NCT04081896Recruiting
Rehab program for adults with spine pain
This trial studies whether a prescribed physical therapy (rehab) program helps people with spine pain. It may help by improving pain and function when a clinician has already recommended rehabilitation.
San Diego, CaliforniaAges 18–89 - NCT07226258RecruitingPhase 3
Testing SL1002 for knee pain caused by osteoarthritis
This trial tests a study drug called SL1002 to see if it reduces knee pain from osteoarthritis. It may be an option for people with chronic knee pain who haven't found enough relief from current treatments.
San Diego, CaliforniaAges 40 years+ - NCT07463430Enrolling by invitationPhase 4
Suzetrigine for pain after non-mastectomy breast surgery
This trial tests a new pain medication, suzetrigine, for people having breast surgery (not mastectomy) who are expected to have moderate pain. It checks if this drug works well compared to standard options.
San Diego, CaliforniaAges 18 years+ - NCT07301177Recruiting
Magnetic stimulation for veterans with nerve pain after injury
This study tests whether a non-invasive magnetic stimulation treatment can help veterans with long-term nerve pain after an injury or surgery. It may offer a drug-free option to reduce pain and improve quality of life.
San Diego, CaliforniaAges 18 years+ - NCT06273462RecruitingPhase 2
Testing PEA for Chronic Inflammatory Pain
This study tests a natural supplement called palmitoylethanolamide (PEA) to see if it can help people with long-term inflammatory pain that hasn't gotten better with other treatments.
San Diego, CaliforniaAges Any age - NCT05351801RecruitingPhase 2
Test cannabis-based treatment for nerve pain
This Phase 2 study tests cannabis-derived products to see if they reduce neuropathic (nerve-related) pain in veterans. It may help people whose pain is persistent and causes significant daily impact, especially if certain exam tests show allodynia (pain from normally non-painful touch).
San Diego, CaliforniaAges 21 years+ - NCT06393101RecruitingPhase 1
High-CBD cannabis extract for complex regional pain syndrome treatment
This study tests a high-CBD cannabis extract (BRC-002) to see if it can help reduce pain and improve health in people with Complex Regional Pain Syndrome (CRPS). Participants will not use opioids or other cannabis during the study.
San Diego, CaliforniaAges 21–75 - NCT05986292RecruitingPhase 2
Study of new treatments for chronic pain
This study tests new treatments for chronic pain that lasts at least 3 months. Participants must stop their regular pain medicines and use only a rescue painkiller if needed. The goal is to find better ways to manage long-term pain.
San Diego, CaliforniaAges 18 years+ - NCT05437575RecruitingPhase 3
Testing pain medicine given before arrival to a trauma center
This study tests whether giving pain medicine soon after an injury (before you reach the trauma center) improves comfort and care. You might be eligible if you’re transported to a participating trauma center and meet specific shock and pain levels.
San Diego, CaliforniaAges 18 years+ - NCT07290361Recruiting
Physical therapy for spine pain in primary care
This trial tests a program that connects people with spine pain (neck or back pain) from their primary care clinic to a physical therapist. The goal is to see if this approach helps patients get more timely and effective care.
San Diego, CaliforniaAges 18 years+ - NCT06917404RecruitingPhase 3
Knee osteoarthritis pain study: comparing a new injection to placebo
This phase 3 study tests whether a medicine called pentosan polysulfate sodium (PPS), given as a shot under the skin, reduces pain in people with knee osteoarthritis. It compares PPS to a placebo (a shot with no active medicine) to see if it is safe and effective.
Chula Vista, CaliforniaAges 18 years+
Hear when a new Pain trial opens near San Diego, CA
We’ll email you when one opens near San Diego, CA — at most once a week, no account needed, unsubscribe anytime.
Pain trials in other cities
Where these studies are running near San Diego
Institutions with a site for the recruiting pain studies listed above.
- University of California San Diego · 7 studies
- Artemis Institute for Clinical Research · 4 studies
- Naval Medical Center San Diego · 3 studies
- TriWest Research Associates · 2 studies
- VA San Diego Healthcare System · 2 studies
- Altman Clinical and Translational Research Institute
- Coastal Research Institute
- Encompass Clinical Research
What taking part in a pain study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting pain studies in California.
Common questions
- Are there pain clinical trials near San Diego?
- Yes. We're currently tracking 49 recruiting pain studies with a site near San Diego, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pain study near San Diego?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in San Diego to take part?
- Not necessarily. These studies have a site near San Diego, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pain studies open near San Diego regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.