Clinical trials
Parkinson clinical trials
Below are recruiting parkinson clinical trials, each written for real people, not researchers. We’re tracking 749 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03025334Recruiting
Brain stimulation study for thinking changes in Parkinson’s
This study tests whether a non-invasive brain stimulation approach (tDCS) can improve thinking and memory in people with Parkinson’s disease. You may be invited because your Parkinson’s is typical and your memory testing shows you do not have dementia.
Winnipeg, ManitobaAges 40 years+ - NCT03174938Recruiting
BioFINDER 2 study for healthy aging and memory problems
This study uses brain scans and a spinal fluid test to better understand memory and thinking changes in different groups, from people with healthy thinking to early or established dementia. If you qualify, it may help researchers learn what’s driving these conditions and how they progress.
ÄngelholmAges 20–100 - NCT03457493RecruitingPhase 1/Phase 2
TSPO brain scan study in Parkinson’s disease
This trial looks at brain inflammation in people with Parkinson’s using a special PET scan. The goal is to understand how brain immune activity may relate to Parkinson’s, and how the scan results change over time.
Birmingham, AlabamaAges 30 years+ - NCT03836950RecruitingPhase 1/Phase 2
Brain stimulation to improve thinking in Parkinson’s
This trial studies a noninvasive treatment called rTMS to help improve thinking and memory in people with Parkinson’s who have mild cognitive problems. It may help strengthen brain function, but it also has strict safety and eligibility rules to protect against seizure and metal-related risks.
Chicago, IllinoisAges 50 years+ - NCT04087031Recruiting
Tech-based rehab for early Parkinson’s symptoms in older adults
This trial tests an innovative, technology-supported rehabilitation program to help older adults with early-stage Parkinson’s disease improve daily function. It may be helpful if your symptoms are mild and your treatments have been stable for at least a month.
AnconaAges 65 years+ - NCT04426786Recruiting
Exercise study to improve brain energy in Parkinson’s
This trial tests whether a structured exercise program can change how your brain uses energy in Parkinson’s disease. It may help improve symptoms or brain-related measures, especially in people who currently exercise very little.
Vancouver, British ColumbiaAges 40–80 - NCT04477785Recruiting
Study to track Parkinson’s signs using imaging, spinal fluid, and genes
This study is building a large, detailed group of people—some with Parkinson’s and some at higher risk—to understand early changes over time. It uses brain imaging (DaTscan SPECT), sometimes spinal fluid tests (lumbar puncture), and genetic information to help researchers better measure disease and develop future treatments.
Birmingham, AlabamaAges 30 years+ - NCT04496973Recruiting
Parkinson’s disease research registry for adults
This registry asks people with Parkinson’s disease to join a research program at the University of Delaware. Being in the registry may help you get invited to investigator-led studies that could improve understanding or treatment of Parkinson’s.
Newark, DelawareAges 21–100 - NCT04616508Recruiting
Online arm movement training for people with Parkinson’s
This study uses online tasks to look at how people with Parkinson’s control reaching movements. You may benefit by contributing to research that could improve understanding and future treatments for movement problems.
Newark, DelawareAges 18–85 - NCT04643327RecruitingPhase 2
Levetiracetam study to lower dementia risk in Parkinson’s
This Phase 2 study tests whether an added medication strategy can change brain targets linked to memory decline in people with Parkinson’s disease, including those with no memory problems or mild memory changes. It may help lower risk of developing dementia, but you must be able to safely do MRI scans and meet other health and medication rules.
Brisbane, QueenslandAges Any age - NCT04650932Recruiting
Study tests new stimulation settings for advanced Parkinson’s
This study looks at whether changing how deep brain stimulation (DBS) pulses are delivered can improve symptoms in people with advanced Parkinson’s disease. You may be eligible if you already have a specific Boston Scientific DBS device and have had it implanted for at least 3 months.
Sacramento, CaliforniaAges 18 years+ - NCT04664634RecruitingPhase 3
Digital treatment for drooling and swallowing in Parkinson’s
This trial tests a smartphone/tablet digital program meant to help with drooling (sialorrhea) and swallowing problems in people with Parkinson’s disease. If you’re eligible, you’ll use the platform during clinic study visits to see whether it can improve symptoms and safety.
Evanston, IllinoisAges 22 years+ - NCT04691661RecruitingPhase 2
Test drug radotinib for early Parkinson’s disease
This Phase 2 study tests whether radotinib is safe and tolerable, and whether it can help people with early Parkinson’s disease. It also checks how the body absorbs and processes the drug.
LilleAges 40–80 - NCT04715984Recruiting
Testing brain-circuit targets during DBS surgery in Parkinson’s
This study looks at how brain connections involved in movement may relate to thinking and memory problems in Parkinson’s disease. It happens during a deep brain stimulation (DBS) operation, using tests while the surgeon is placing an electrode.
Nashville, TennesseeAges 40 years+ - NCT04724941Recruiting
Screening for alpha-synuclein in early Parkinson’s risk
This study looks for changes in a protein called alpha-synuclein in people who may be in the early “prodromal” stage before Parkinson’s symptoms fully appear. It may help researchers find early markers and understand who is more likely to develop Parkinson’s disease.
KielAges 50–99 - NCT04731246Recruiting
Eye-movement testing in people with early Parkinson’s
This study uses video recordings of your eye movements to learn more about Parkinson’s disease. It may help researchers better tell Parkinson’s apart from other movement conditions and understand how the disease affects the brain early on.
MonacoAges 18 years+ - NCT04735627Recruiting
Real-time monitoring of levodopa levels in Parkinson’s
This study checks whether measuring levodopa (a Parkinson medicine) in real time can help better understand Parkinson medication effects. You may be asked to wear/perform study monitoring while taking your usual carbidopa/levodopa tablets.
San Diego, CaliforniaAges 40–85 - NCT04804202Recruiting
Virtual cycling program for people with Parkinson disease
This study tests whether a virtual, guided stationary bike exercise program is safe and helpful for people with Parkinson disease. It may help improve movement and fitness by letting you ride at home or in a controlled setting while using visual and audio guidance.
Newark, New JerseyAges 45–75 - NCT07698236Enrolling by invitation
Temporal interference brain stimulation for Parkinson's disease
This trial tests a new non-invasive brain stimulation method called temporal interference to see if it can improve symptoms of Parkinson's disease. It is for people aged 40 to 80 who are on stable Parkinson's medications and have mild to moderate symptoms.
ShanghaiAges 40–80 - NCT07151378RecruitingPhase 3
Intestinal gel for Parkinson's mood and behavior problems
This trial tests a gel form of levodopa (called Lecigon) given through a tube into the intestine to see if it helps reduce mood swings, impulsive behaviors, and other mental side effects in people with Parkinson's who already have motor fluctuations. It is for people who have had Parkinson's for at least 5 years and are between 18 and 75 years old.
Saarlouis, SaarlandAges 18–75 - NCT04941326Recruiting
Spinal mobilization for breathing in Parkinson’s disease
This study tests whether a hands-on therapy to the spine can improve breathing measures in people with Parkinson’s disease. If you qualify, you would receive spinal mobilization and have your breathing assessed to see if it helps.
BoluAges 50–85 - NCT05025254Recruiting
Online thinking tests for people with Parkinson’s disease
This study tests online “thinking” (cognitive) abilities in people with Parkinson’s disease. It may help researchers better understand how thinking changes over time and how tests can be done from home.
Montreal, QuebecAges 45–90 - NCT05065151Recruiting
Studying motivation in Parkinson’s using brain stimulation recordings
This study looks at what drives motivation in people with Parkinson’s disease (or dystonia) by using recordings from an implanted brain stimulation device. It may help researchers understand brain signals behind motivation and improve future treatments.
San Francisco, CaliforniaAges 18 years+ - NCT05070013Recruiting
Brain stimulation to improve sleep in people with Parkinson’s disease
This study tests an adaptive brain stimulation device to help restore better sleep in people with Parkinson’s disease. You may be eligible if your Parkinson’s motor symptoms are severe despite best medical treatment and you are already being considered for a specific deep brain stimulation surgery.
Omaha, NebraskaAges 18–80
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Common questions
- Are there clinical trials for parkinson?
- Yes. Clin2 currently lists 749 recruiting parkinson studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.