Clinical trials
Parkinsonism clinical trials
Below are recruiting parkinsonism clinical trials, each written for real people, not researchers. We’re tracking 734 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06932692Recruiting
Brain network analysis using 7-Tesla MRI in DBS patients
This study uses advanced brain imaging (7-Tesla MRI and MEG) to understand how deep brain stimulation (DBS) affects brain networks in people with Parkinson's disease or essential tremor. It helps doctors learn how DBS works so they can improve treatment in the future.
Amsterdam, North HollandAges 18 years+ - NCT07195825RecruitingPhase 1
Gene therapy BBM-P002 for Parkinson's disease safety trial
This trial tests a new gene therapy called BBM-P002 for Parkinson's disease. It aims to see if the treatment is safe and tolerable, and may help people with moderate to advanced Parkinson's who have had the condition for at least 5 years.
Shanghai, Shanghai MunicipalityAges 40–70 - NCT07202494Recruiting
Brain aging and resilience MRI study
This study uses powerful MRI scans to understand how the brain ages and why some people stay healthy while others develop neurological diseases like multiple sclerosis or Alzheimer's. It compares healthy volunteers to people with certain conditions, and all participants get a detailed brain MRI.
MarseilleAges 18–90 - NCT07187843Recruiting
Parkinson's type study: brain-first vs body-first
This study looks at how Parkinson's disease affects thinking, movement, and brain health differently depending on whether it starts in the brain or the body first. Participants will have tests and scans to track these differences over time.
Reggio EmiliaAges 18 years+ - NCT07193303Recruiting
Mental imagery for arm and hand skills in Parkinson's
This study tests if mental imagery exercises can help improve upper body movement in people with Parkinson's disease. It may offer a safe, drug-free way to practice daily tasks.
Kahramanmaraş, OnikişubatAges 40–75 - NCT07193355Recruiting
Motor imagery training for Parkinson's disease
This trial tests if thinking about movements (motor imagery) can help improve hand function in people with Parkinson's disease. It may offer a non-drug way to manage symptoms.
Kahramanmaraş, OnikişubatAges 40–75 - NCT07176286RecruitingPhase 2
PET scan study for diagnosing Lewy body dementia
This trial is testing a special PET scan that uses a radioactive tracer (18F-mFBG) to see how much it is taken up by the heart. The goal is to help tell Lewy body disease (Parkinson's or Lewy body dementia) apart from other brain disorders.
Houston, TexasAges 18 years+ - NCT07172295Recruiting
Low-intensity focused ultrasound for hand tremor
This study uses low-intensity focused ultrasound to stimulate a deep brain area and reduce hand tremors. It is for people with Parkinson's disease, essential tremor, or dystonic tremor whose medications don't work well enough.
Hsinchu, Hsinchu CityAges 18–80 - NCT05395624RecruitingPhase 1/Phase 2
Safety imaging study of a PET tracer in ALS, Alzheimer, MS, Parkinson
This early-phase study tests the safety of a radioactive tracer (“18F-OP-801”) and how the tracer moves through the body (biodistribution) in people with ALS, Alzheimer’s disease, multiple sclerosis, Parkinson’s disease, and in healthy volunteers. It also measures how the body processes the tracer (“pharmacokinetics”) to support future studies.
San Francisco, CaliforniaAges 18–80 - NCT05919485Recruiting
Brain stimulation study for mild cognitive problems in Parkinson’s
This trial tests whether a type of noninvasive brain stimulation (tDCS) can improve thinking and memory in people with mild cognitive impairment in Parkinson’s disease. You may be eligible if you have these diagnoses, are on stable medications, and can safely complete brain scan/testing.
Antalya, AlanyaAges 45–80 - NCT06657274Recruiting
Digital brain training for early memory problems
This study tests a smart digital program (app or computer-based) to help with memory, thinking, and daily life in people with early Parkinson's, mild cognitive impairment, or early memory concerns. It uses brain stimulation (TMS) along with cognitive exercises.
Brescia, ITAges 18–85 - NCT07145190Recruiting
Starting Sublingual Apomorphine for Parkinson's OFF Episodes
This study looks at how patients start and adjust a new medicine (sublingual apomorphine, or SL-APO) for Parkinson's disease OFF episodes. OFF episodes are times when Parkinson's symptoms come back between medicine doses. If you are about to start SL-APO for the first time, this trial may be a good fit.
BerlinAges 18 years+ - NCT06295263Recruiting
AI for diagnosing and treating brain diseases in older adults
This study uses artificial intelligence to help diagnose and treat brain diseases that affect older adults, such as Parkinson's and Alzheimer's. Researchers will compare AI methods with standard care to see if they can improve diagnosis and treatment.
Jinan, ShandongAges 8–100 - NCT07115394Recruiting
Brain wave tracking during DBS for movement disorders
This study uses EEG (a non-invasive scalp recording) to measure brain signals while deep brain stimulation (DBS) is active. It aims to better understand how DBS affects brain activity in people with Parkinson's disease, essential tremor, or dystonia.
HamburgAges 35–85 - NCT06684782Recruiting
Restless leg syndrome in Thai Parkinson's patients
This trial is looking at how common restless leg syndrome is in people with Parkinson's disease in Thailand. It aims to better understand the link between the two conditions so doctors can improve care for people with both.
Bangkok, BangkokAges 18–80 - NCT07078422Recruiting
Can a wrist device reduce hand tremors at home?
This study tests a wrist-worn device that uses gentle mechanical stimulation to help control hand tremors caused by essential tremor or Parkinson's disease. You use the device at home and report how well it works for you.
Cambridge, MassachusettsAges 18 years+ - NCT07056348Recruiting
Brain stimulation to improve movement in Parkinson's or tremor
This study tests brain stimulation in a region called VOP/VIM to see if it can improve motor function. It is for people with movement disorders who are already getting deep brain stimulation (DBS) surgery.
Pittsburgh, PennsylvaniaAges 18–80 - NCT04375280Recruiting
Study of mobility problems in people with long-term illnesses
This study observes how people with chronic health conditions affect their ability to move and do everyday activities. It may help researchers better understand mobility limits and what factors influence them.
Clermont-FerrandAges 18–90 - NCT07049341Enrolling by invitation
A pilot trial of the MemorEM device for neurological diseases
This trial tests a device called MemorEM to see how patients with neurological diseases like Alzheimer's or Parkinson's experience it. It aims to understand if the device is comfortable and easy to use.
Tampa, FloridaAges 45–100 - NCT07044973Recruiting
Focused ultrasound for Parkinson's disease tremor
This trial uses focused ultrasound to treat tremor and movement problems in Parkinson's disease. It targets a specific brain area without surgery, and may help if your symptoms are worse on one side and not fully controlled by medication.
Beijing, Beijing MunicipalityAges 22 years+ - NCT07038486Recruiting
Testing a digital tool for Parkinson's symptoms
This study tests a digital tool (NMS Assist) to help people with Parkinson's and their caregivers track and manage non-motor symptoms like mood, sleep, and thinking changes. Participation takes place from home using a smartphone or tablet.
Newcastle upon Tyne, Tyne and WearAges 18 years+ - NCT07018388Enrolling by invitation
Comparing two brain targets for non-invasive stimulation in Parkinson's
This study compares two areas of the brain (subthalamic nucleus and globus pallidus interna) for stimulation using a new non-invasive technique called tTIS. The goal is to see which area works better to improve Parkinson's symptoms.
Shanghai, Shanghai MunicipalityAges 50–85 - NCT06997484RecruitingPhase 1
Testing safety of HL-400 in healthy adults
This study tests a new drug called HL-400 for the first time in people. It checks how safe the drug is and how the body handles it, to see if it could be developed for future patients.
Baltimore, MarylandAges 18–65 - NCT06994728Recruiting
How DBS affects vision and freezing of gait in Parkinson's
This trial looks at how deep brain stimulation (DBS) affects the way you see and move, and how that relates to freezing of gait (when your feet suddenly feel stuck). If you have Parkinson's disease, already have a DBS device, and experience freezing, this study may help researchers understand your symptoms better.
Charleston, South CarolinaAges 18 years+
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Common questions
- Are there clinical trials for parkinsonism?
- Yes. Clin2 currently lists 734 recruiting parkinsonism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinsonism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinsonism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.