Clinical trials
Parkinson's Disease and Parkinsonism clinical trials
Below are recruiting parkinson's disease and parkinsonism clinical trials, each written for real people, not researchers. We’re tracking 736 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04179695Recruiting
Testing a new communication aid to improve patient-centered care
This study tests a new tool meant to help patients and healthcare teams communicate better and support “patient-centered care.” You may be invited to use the tool and complete study activities during your neurology care visits.
LilleAges 18–90 - NCT04366804Recruiting
Testing two non-movement symptom questionnaires in Parkinson’s
This study checks whether two written questionnaires can reliably measure “non-motor” symptoms in people with Parkinson’s disease. It may help future care by making symptom tracking easier and more accurate.
BesançonAges 30–75 - NCT04735172Recruiting
Brain scan to compare Parkinson chemical signals in early patients
This study uses a special 7‑Tesla MRI brain scan to measure tiny chemical (metabolite) differences in specific deep brain areas. It compares newly diagnosed, early-stage Parkinson’s patients who are not on Parkinson medication with healthy volunteers.
Clermont-FerrandAges 18–75 - NCT05413291Recruiting
Study of movement disorders over time
This study follows people (or family members of people) who have or might have a movement disorder to better understand how symptoms change over time. You may be asked to attend study visits and complete study procedures for the duration of the study.
Bethesda, MarylandAges 2–100 - NCT05590637RecruitingPhase 4
Compare antipsychotic medicines for Parkinson or Lewy body psychosis
This study compares two medicines—quetiapine and pimavanserin—in people with psychosis caused by Parkinson’s disease or Lewy body dementia, looking at how they work over time. You might join if you are starting an antipsychotic for the first time and your clinician can safely manage either option.
San Antonio, TexasAges Any age - NCT06098612RecruitingEarly Phase 1
PET imaging study for Parkinson's and related disorders
This study uses a new PET scan tracer called [11C]SY08 to take pictures of the brain in people with Parkinson's, multiple system atrophy, or dementia with Lewy bodies. It aims to see if this tracer can help better understand and tell apart these conditions.
Charlestown, MassachusettsAges 50–80 - NCT06460038RecruitingPhase 2
Medication study for constipation in Parkinson's
This study tests whether a medication called tenapanor can help relieve constipation in people with Parkinson's disease. If you have Parkinson's and have been struggling with constipation for at least 6 months, this trial may offer a new option to improve bowel regularity.
Waterloo, IowaAges 50–89 - NCT07569120Recruiting
Brain Chemistry and Aging: Healthy and Parkinson's Study
This research uses brain imaging scans to study how a chemical messenger in the brain (called noradrenaline) changes as people age and in Parkinson's disease. The goal is to better understand how this brain system works and may help develop future treatments.
BronAges 20–80 - NCT06505460Recruiting
Brain stimulation for Parkinson's freezing of gait
This study is testing if two brain-stimulation treatments—deep brain stimulation (DBS) or focused ultrasound—can help reduce freezing of gait (a common, frustrating symptom where your feet feel stuck when walking) in people with Parkinson's. Researchers will use brain scans and electrical recordings to understand how these treatments work.
TaichungAges 20–90 - NCT06519279Recruiting
Freezing of gait study for Parkinson's patients
This study looks at how Parkinson's disease affects freezing of gait (a sudden feeling of being stuck while walking). It may help researchers better understand this symptom and improve future treatments. You may be able to join if you can walk 10 meters without help and don't have a deep brain stimulator.
Tel AvivAges 18 years+ - NCT06596187Recruiting
Study of muscle tightness in spinal cord injury and Parkinson's
This study looks at muscle tightness (hypertonia) in people with spinal cord injury, Parkinson's disease, and healthy volunteers. It aims to better understand and measure different types of stiffness to improve treatments.
TaoyuanAges 20 years+ - NCT06684782Recruiting
Restless leg syndrome in Thai Parkinson's patients
This trial is looking at how common restless leg syndrome is in people with Parkinson's disease in Thailand. It aims to better understand the link between the two conditions so doctors can improve care for people with both.
Bangkok, BangkokAges 18–80 - NCT02071134Recruiting
Registry study for Vercise deep brain stimulation patients
This study keeps a record of people who receive the Vercise deep brain stimulation system. It helps doctors learn how the treatment is used in real-world care and how patients do over time.
Aliso Viejo, CaliforniaAges 18 years+ - NCT06815263Recruiting
Listener training to understand speech in Parkinson's
This trial tests a listener training program to help people better understand speech that is hard to understand due to Parkinson's disease. It may help if you have Parkinson's and a speech problem called hyperkinetic dysarthria.
Tallahassee, FloridaAges 18 years+ - NCT06891703RecruitingEarly Phase 1
PET imaging study for Parkinson's and related conditions
This trial uses a new imaging agent (like a dye) to see signs of Parkinson's disease in the brain. If you have Parkinson's or a related condition like Lewy body dementia or multiple system atrophy, this scan may help researchers better understand these illnesses.
SolnaAges 20 years+ - NCT06951906RecruitingPhase 4
Brain imaging study of freezing of gait after deep brain stimulation
This trial is for people with Parkinson's disease who experience freezing of gait (feeling like your feet are stuck to the floor) and are already scheduled to have deep brain stimulation surgery. The study will use MRI brain scans to understand how the surgery helps improve walking.
Charleston, South CarolinaAges 40 years+ - NCT07078422Recruiting
Can a wrist device reduce hand tremors at home?
This study tests a wrist-worn device that uses gentle mechanical stimulation to help control hand tremors caused by essential tremor or Parkinson's disease. You use the device at home and report how well it works for you.
Cambridge, MassachusettsAges 18 years+ - NCT07682311Recruiting
Adjusting brain stimulation automatically for Parkinson's
This study tests a new way to adjust deep brain stimulation (DBS) automatically during the day to better control Parkinson's symptoms. It is for people who already have a Percept DBS device but still have motor fluctuations.
San Francisco, CaliforniaAges 25–75 - NCT07428447Recruiting
Skin test to predict Parkinson's risk in essential tremor
This study uses a skin biopsy to check for a protein linked to Parkinson's disease. It aims to see if people with essential tremor who have this protein are more likely to develop Parkinson's disease.
Scottsdale, ArizonaAges 50–85 - NCT07284784RecruitingPhase 2/Phase 3
Buntanetap for Parkinson's disease study
This trial tests an investigational drug called buntanetap in people with Parkinson's disease. It aims to see if the drug can improve symptoms. There are two groups: those who've taken buntanetap before (Cohort 1) and those with a deep brain stimulator (DBS) implant for at least a year (Cohort 2).
Birmingham, AlabamaAges 40–85 - NCT07336199Recruiting
Pairing your ratings with DBS programming
This study looks at how your own ratings of your Parkinson's symptoms can help fine-tune your deep brain stimulation (DBS) settings. It is for people with Parkinson's who already have a DBS device that can record brain activity.
MünchenAges 35–80 - NCT07348705Recruiting
Testing a new DBS programming method for Parkinson's
This study tests a new way to program deep brain stimulation (DBS) using brain signals, which may improve symptom control. It is for people with Parkinson's who have a Medtronic Percept DBS device and are ready for their first programming session.
Gainesville, FloridaAges 21–89 - NCT00575081Recruiting
Brain mapping during stereotactic procedures
This study builds a “brain atlas” by collecting information during stereotactic brain procedures. It may help doctors better plan and understand these brain procedures in the future.
Nashville, TennesseeAges 6–90 - NCT01581580Recruiting
Deep brain stimulation surgery for movement disorders
This study looks at whether deep brain stimulation surgery can help people with certain movement problems, chosen by a specialized team. You may be considered if medicines (or other treatments) aren’t controlling your symptoms well enough or if the condition causes major disability.
Bethesda, MarylandAges 18–99
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Common questions
- Are there clinical trials for parkinson's disease and parkinsonism?
- Yes. Clin2 currently lists 736 recruiting parkinson's disease and parkinsonism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson's disease and parkinsonism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson's disease and parkinsonism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.