Clinical trials
Parkinson's Disease and Parkinsonism clinical trials
Below are recruiting parkinson's disease and parkinsonism clinical trials, each written for real people, not researchers. We’re tracking 723 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07284784RecruitingPhase 2/Phase 3
Buntanetap for Parkinson's disease study
This trial tests an investigational drug called buntanetap in people with Parkinson's disease. It aims to see if the drug can improve symptoms. There are two groups: those who've taken buntanetap before (Cohort 1) and those with a deep brain stimulator (DBS) implant for at least a year (Cohort 2).
Birmingham, AlabamaAges 40–85 - NCT04366804Recruiting
Testing two non-movement symptom questionnaires in Parkinson’s
This study checks whether two written questionnaires can reliably measure “non-motor” symptoms in people with Parkinson’s disease. It may help future care by making symptom tracking easier and more accurate.
BesançonAges 30–75 - NCT07195825RecruitingPhase 1
Gene therapy BBM-P002 for Parkinson's disease safety trial
This trial tests a new gene therapy called BBM-P002 for Parkinson's disease. It aims to see if the treatment is safe and tolerable, and may help people with moderate to advanced Parkinson's who have had the condition for at least 5 years.
Shanghai, Shanghai MunicipalityAges 40–70 - NCT07115394Recruiting
Brain wave tracking during DBS for movement disorders
This study uses EEG (a non-invasive scalp recording) to measure brain signals while deep brain stimulation (DBS) is active. It aims to better understand how DBS affects brain activity in people with Parkinson's disease, essential tremor, or dystonia.
HamburgAges 35–85 - NCT06684782Recruiting
Restless leg syndrome in Thai Parkinson's patients
This trial is looking at how common restless leg syndrome is in people with Parkinson's disease in Thailand. It aims to better understand the link between the two conditions so doctors can improve care for people with both.
Bangkok, BangkokAges 18–80 - NCT07078422Recruiting
Can a wrist device reduce hand tremors at home?
This study tests a wrist-worn device that uses gentle mechanical stimulation to help control hand tremors caused by essential tremor or Parkinson's disease. You use the device at home and report how well it works for you.
Cambridge, MassachusettsAges 18 years+ - NCT06951906RecruitingPhase 4
Brain imaging study of freezing of gait after deep brain stimulation
This trial is for people with Parkinson's disease who experience freezing of gait (feeling like your feet are stuck to the floor) and are already scheduled to have deep brain stimulation surgery. The study will use MRI brain scans to understand how the surgery helps improve walking.
Charleston, South CarolinaAges 40 years+ - NCT06931483Enrolling by invitation
Brain stimulation for Parkinson's motor symptoms
This trial uses a new type of non-invasive brain stimulation to target a deep brain area that controls movement. It aims to improve motor symptoms like stiffness and slowness in people with Parkinson's disease, without needing surgery.
Hefei, AnhuiAges 50–80 - NCT06891703RecruitingEarly Phase 1
PET imaging study for Parkinson's and related conditions
This trial uses a new imaging agent (like a dye) to see signs of Parkinson's disease in the brain. If you have Parkinson's or a related condition like Lewy body dementia or multiple system atrophy, this scan may help researchers better understand these illnesses.
SolnaAges 20 years+ - NCT06815263Recruiting
Listener training to understand speech in Parkinson's
This trial tests a listener training program to help people better understand speech that is hard to understand due to Parkinson's disease. It may help if you have Parkinson's and a speech problem called hyperkinetic dysarthria.
Tallahassee, FloridaAges 18 years+ - NCT06685510Enrolling by invitation
Deep brain stimulation outcomes and electrode position in Parkinson's
This study looks at how the placement of electrodes during deep brain stimulation (DBS) for Parkinson's disease affects recovery and motor symptoms right after surgery. It could help doctors improve DBS outcomes for people with Parkinson's.
Nanchang, JiangxiAges 18–75 - NCT05698810Recruiting
Study exams practice for upcoming research
This trial checks whether it’s practical and workable to set up study-related exams before planned research. It mainly recruits adults who can consent and be contacted, so the team can prepare future studies smoothly.
GrenobleAges 18 years+ - NCT05590637RecruitingPhase 4
Compare antipsychotic medicines for Parkinson or Lewy body psychosis
This study compares two medicines—quetiapine and pimavanserin—in people with psychosis caused by Parkinson’s disease or Lewy body dementia, looking at how they work over time. You might join if you are starting an antipsychotic for the first time and your clinician can safely manage either option.
San Antonio, TexasAges Any age - NCT06098612RecruitingEarly Phase 1
PET imaging study for Parkinson's and related disorders
This study uses a new PET scan tracer called [11C]SY08 to take pictures of the brain in people with Parkinson's, multiple system atrophy, or dementia with Lewy bodies. It aims to see if this tracer can help better understand and tell apart these conditions.
Charlestown, MassachusettsAges 50–80 - NCT05514106Enrolling by invitationPhase 4
MIBG heart scan study for aging and neurologic conditions
This Phase 4 study tests how an iodine-based heart scan (a special imaging test) works in people with certain neurologic diagnoses and aging-related conditions. It may help researchers better understand the heart-brain connection in these disorders and improve future care.
Rochester, MinnesotaAges 40–90 - NCT05413291Recruiting
Study of movement disorders over time
This study follows people (or family members of people) who have or might have a movement disorder to better understand how symptoms change over time. You may be asked to attend study visits and complete study procedures for the duration of the study.
Bethesda, MarylandAges 2–100 - NCT04179695Recruiting
Testing a new communication aid to improve patient-centered care
This study tests a new tool meant to help patients and healthcare teams communicate better and support “patient-centered care.” You may be invited to use the tool and complete study activities during your neurology care visits.
LilleAges 18–90 - NCT04735172Recruiting
Brain scan to compare Parkinson chemical signals in early patients
This study uses a special 7‑Tesla MRI brain scan to measure tiny chemical (metabolite) differences in specific deep brain areas. It compares newly diagnosed, early-stage Parkinson’s patients who are not on Parkinson medication with healthy volunteers.
Clermont-FerrandAges 18–75 - NCT04061135Recruiting
Study brain and movement patterns in Parkinson’s or tremor
This study looks at brain signals, thinking, and movement behaviors in people who have Parkinson’s disease or essential tremor and are being considered for deep brain stimulation (DBS) surgery. It may help researchers better understand how DBS affects the brain and day-to-day function.
Birmingham, AlabamaAges 18 years+ - NCT02119611Recruiting
Deep brain stimulation for Parkinson’s, dystonia, or tremor
This study tests deep brain stimulation (DBS), a therapy that sends electrical signals to the brain, for movement problems like Parkinson’s disease, dystonia, and essential tremor. It may help people whose symptoms are not controlled enough with medications, or who already have a DBS device and need ongoing management.
Bethesda, MarylandAges 18–100 - NCT01581580Recruiting
Deep brain stimulation surgery for movement disorders
This study looks at whether deep brain stimulation surgery can help people with certain movement problems, chosen by a specialized team. You may be considered if medicines (or other treatments) aren’t controlling your symptoms well enough or if the condition causes major disability.
Bethesda, MarylandAges 18–99 - NCT02071134Recruiting
Registry study for Vercise deep brain stimulation patients
This study keeps a record of people who receive the Vercise deep brain stimulation system. It helps doctors learn how the treatment is used in real-world care and how patients do over time.
Aliso Viejo, CaliforniaAges 18 years+ - NCT01453127Enrolling by invitationPhase 4
DaTscan scan for aging and movement brain conditions
This trial uses a special brain scan called DaTscan to study how certain brain conditions change with aging and over time. It may help researchers better understand movement and other neurodegenerative conditions and who may benefit from future treatments.
Rochester, MinnesotaAges 40–90 - NCT00575081Recruiting
Brain mapping during stereotactic procedures
This study builds a “brain atlas” by collecting information during stereotactic brain procedures. It may help doctors better plan and understand these brain procedures in the future.
Nashville, TennesseeAges 6–90
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Common questions
- Are there clinical trials for parkinson's disease and parkinsonism?
- Yes. Clin2 currently lists 723 recruiting parkinson's disease and parkinsonism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson's disease and parkinsonism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson's disease and parkinsonism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.