Clinical trials
Parkinson's Disease and Parkinsonism clinical trials
Below are recruiting parkinson's disease and parkinsonism clinical trials, each written for real people, not researchers. We’re tracking 739 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07348705Recruiting
Testing a new DBS programming method for Parkinson's
This study tests a new way to program deep brain stimulation (DBS) using brain signals, which may improve symptom control. It is for people with Parkinson's who have a Medtronic Percept DBS device and are ready for their first programming session.
Gainesville, FloridaAges 21–89 - NCT00575081Recruiting
Brain mapping during stereotactic procedures
This study builds a “brain atlas” by collecting information during stereotactic brain procedures. It may help doctors better plan and understand these brain procedures in the future.
Nashville, TennesseeAges 6–90 - NCT01581580Recruiting
Deep brain stimulation surgery for movement disorders
This study looks at whether deep brain stimulation surgery can help people with certain movement problems, chosen by a specialized team. You may be considered if medicines (or other treatments) aren’t controlling your symptoms well enough or if the condition causes major disability.
Bethesda, MarylandAges 18–99 - NCT02119611Recruiting
Deep brain stimulation for Parkinson’s, dystonia, or tremor
This study tests deep brain stimulation (DBS), a therapy that sends electrical signals to the brain, for movement problems like Parkinson’s disease, dystonia, and essential tremor. It may help people whose symptoms are not controlled enough with medications, or who already have a DBS device and need ongoing management.
Bethesda, MarylandAges 18–100 - NCT07604116RecruitingPhase 1
Safety study of SST001 in Parkinson's and MSA patients
This is an early-stage study testing a new experimental medicine called SST001 in people with Parkinson's disease (PD) and multiple system atrophy (MSA), as well as healthy volunteers. The study checks whether SST001 is safe, how the body processes it, and where it goes in the body using imaging scans.
Wuxi, JiangsuAges 40 years+ - NCT01453127Enrolling by invitationPhase 4
DaTscan scan for aging and movement brain conditions
This trial uses a special brain scan called DaTscan to study how certain brain conditions change with aging and over time. It may help researchers better understand movement and other neurodegenerative conditions and who may benefit from future treatments.
Rochester, MinnesotaAges 40–90 - NCT07417280Recruiting
Focused ultrasound for neurological disorders
This trial tests a gentle ultrasound treatment (LIFUS) for people with various brain conditions like epilepsy, tumours, or movement disorders. It aims to see if this non-invasive approach can help where other treatments are being used.
Toronto, OntarioAges 18–85 - NCT07455760Recruiting
Deep brain stimulation and speech sequencing study
This study looks at how deep brain stimulation affects speech in people with Parkinson's disease or essential tremor. It tests whether the stimulation changes the way you say sequences of sounds.
Boston, MassachusettsAges 18 years+ - NCT07509125Recruiting
Ultra-high resolution PET brain scans for aging, dementia, and psychosis
This study uses a new ultra-high resolution PET scanner to look at brain changes in healthy aging, dementia, ALS, movement disorders, and psychosis. It aims to better understand these conditions and improve imaging techniques.
Leuven, Vlaams-BrabantAges 18–90 - NCT07570212Recruiting
Personalized Brain Stimulation for Parkinson's and Similar Disorders
This study tests whether customized transcranial magnetic stimulation (a non-invasive technique that uses magnetic pulses to stimulate brain activity) can help improve symptoms in people with Parkinson's disease, multiple system atrophy, or progressive supranuclear palsy. The treatment is tailored to each person's brain activity patterns.
Beijing, Beijing MunicipalityAges 30–80 - NCT07574164Recruiting
Brain Stimulation to Reduce Tremor in Parkinson's or Essential Tremor
This trial tests a new type of brain stimulation called closed-loop TMS that automatically adjusts to help reduce tremor in people with Parkinson's disease or essential tremor. The goal is to see if this technology can better control shaking than standard treatments.
Oxford, OxfordshireAges 18 years+ - NCT07586501Enrolling by invitation
Brain Health and Immune System Study in Older Adults
This research study examines how the brain's immune system changes in older adults with memory problems, Parkinson's disease, or normal aging. By understanding these changes, researchers hope to better understand neurodegeneration and develop new treatments.
Yantai, ShandongAges 55–75 - NCT07424508Enrolling by invitation
Adaptive brain stimulation for Parkinson's movement symptoms
This trial tests a new type of deep brain stimulation that adapts to your movements to improve walking, balance, and tremors. It is for people with Parkinson's disease who have had symptoms for at least 3 years, are 21 to 75 years old, and already have a special study brain-stimulation device implanted.
San Francisco, CaliforniaAges 21–75 - NCT06931483Enrolling by invitation
Brain stimulation for Parkinson's motor symptoms
This trial uses a new type of non-invasive brain stimulation to target a deep brain area that controls movement. It aims to improve motor symptoms like stiffness and slowness in people with Parkinson's disease, without needing surgery.
Hefei, AnhuiAges 50–80 - NCT06537050Enrolling by invitationPhase 1
Safety study of JX2105 in healthy volunteers
This study tests a new oral drug called JX2105 in healthy people to see how safe it is and how the body handles it. It is a first-in-human phase 1 trial, so participants will help find the right dose and check for any side effects.
Beijing, Beijing MunicipalityAges 18–75 - NCT06164756Enrolling by invitation
Long-term follow-up of the ketamine for Parkinson's trial
This study follows up on people with Parkinson's disease who took part in an earlier trial testing the effects of ketamine. It looks at how they do over a longer period of time.
New Haven, ConnecticutAges 40–80 - NCT06724029Recruiting
Neurosurgery outcomes research for multiple conditions
This study collects data from people having brain or spine surgery for many different conditions. It aims to understand how well different treatments work and how people recover. If you are scheduled for certain brain, spine, or nerve surgeries, you may be able to join.
Bergamo, BGAges 18 years+ - NCT06984757Enrolling by invitation
Brain waves and thinking in Parkinson's disease
This study looks at how brain activity relates to thinking and memory in people with Parkinson's disease, including those with and without cognitive issues, and those with deep brain stimulation. It uses EEG (a non-invasive brain wave recording) and sometimes mild brain stimulation (TMS or tACS) to understand these connections better.
Iowa City, IowaAges 18–99 - NCT02795052Recruiting
Stem cell treatment trial for nerve injury
This study tests whether bone-marrow stem cells can improve nerve function in people with nerve damage that usually doesn’t recover with current care. It also checks whether the treatment is safe and whether people can be followed over time with repeated nerve exams.
Westport, ConnecticutAges 18 years+
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Common questions
- Are there clinical trials for parkinson's disease and parkinsonism?
- Yes. Clin2 currently lists 739 recruiting parkinson's disease and parkinsonism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson's disease and parkinsonism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson's disease and parkinsonism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.