Clinical trials
Parkinson’s disease clinical trials
A movement disorder caused by the loss of dopamine-producing brain cells. We’re tracking 723 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07698236Enrolling by invitation
Temporal interference brain stimulation for Parkinson's disease
This trial tests a new non-invasive brain stimulation method called temporal interference to see if it can improve symptoms of Parkinson's disease. It is for people aged 40 to 80 who are on stable Parkinson's medications and have mild to moderate symptoms.
ShanghaiAges 40–80 - NCT01989013Enrolling by invitation
CranioSacral therapy for people with Parkinson’s disease
This study looks at whether a hands-on therapy called CranioSacral Integrated Therapy can improve symptoms in people with Parkinson’s disease. If you have Parkinson’s, the goal is to see whether this treatment changes how you feel or function.
Ann Arbor, MichiganAges 18 years+ - NCT07666022RecruitingPhase 1
Safety study of MF1 for Parkinson's-related constipation
This early-phase study tests a new treatment called MF1 for Parkinson's-related symptoms, especially constipation. It first checks safety in healthy volunteers, then in people with Parkinson's who have slow bowel movements.
Sumida-ku, TokyoAges 18–85 - NCT07239843Enrolling by invitation
Study of blood markers and mental health in brain diseases
This study looks at how social factors and blood markers relate to psychiatric symptoms in people with brain diseases or mental disorders. It aims to find new ways to understand and diagnose these conditions.
Barcelona, BarcelonaAges 18 years+ - NCT05934188Recruiting
Study how gut signals relate to brain aging and diseases
This study looks at how the gut may influence the brain in normal aging and conditions like Alzheimer’s, Parkinson’s, and multiple sclerosis. It may help researchers understand new ways to measure or treat these brain changes over time.
Venice-Lido, VeniceAges 20–90 - NCT06631742Recruiting
Exergaming for dementia: a fun exercise trial
This trial tests whether playing interactive video games that combine exercise and thinking challenges (called 'exergaming') can help people with dementia. It aims to see if this fun way to move and think can improve memory, daily function, and quality of life.
Wetzikon, Canton of ZurichAges Any age - NCT07674264Recruiting
Breathing therapy for thinking and movement in Parkinson's
This study tests whether a breathing-based therapy (short bursts of controlled air with higher carbon dioxide) can help with thinking and movement in people with Parkinson's disease. It may be an option for those who are not too advanced in their condition and are healthy enough to participate.
Gainesville, FloridaAges 40–75 - NCT07557706RecruitingPhase 1
Vagus Nerve Stimulation to Improve Heart Function in Parkinson's Disease
This study tests a non-invasive ear-based stimulation technique (taVNS) to help regulate heart function in people with Parkinson's disease. The goal is to see if this gentle stimulation can improve blood pressure and heart rate control.
Birmingham, AlabamaAges 18–80 - NCT07370532RecruitingPhase 2
Etoricoxib for Parkinson's disease
This study tests if etoricoxib, an anti-inflammatory drug, can help people with Parkinson's disease. You may join if you have a confirmed diagnosis and are not using other anti-inflammatory drugs.
Al MansurahAges 50–70 - NCT07229664RecruitingPhase 2/Phase 3
Vinpocetine for Parkinson's disease
This trial tests if adding vinpocetine to standard levodopa treatment can help Parkinson's disease patients. It aims to see if this combination improves symptoms.
TantaAges 50–70 - NCT05919485Recruiting
Brain stimulation study for mild cognitive problems in Parkinson’s
This trial tests whether a type of noninvasive brain stimulation (tDCS) can improve thinking and memory in people with mild cognitive impairment in Parkinson’s disease. You may be eligible if you have these diagnoses, are on stable medications, and can safely complete brain scan/testing.
Antalya, AlanyaAges 45–80 - NCT06092125Recruiting
Brain disease imaging study with PET/MR scans
This trial uses advanced PET and MR scans to better understand and diagnose brain diseases like Alzheimer's, Parkinson's, epilepsy, and brain tumors. It may help identify new ways to track these conditions.
Beijing, Beijing MunicipalityAges 18–60 - NCT06793735Recruiting
Virtual reality app for memory and thinking problems
This trial tests a virtual reality app you can use at home to help with early memory or thinking problems. It may be an option if you have mild cognitive impairment or notice your thinking is slowing down.
Messina, ItalyAges 40–80 - NCT04388969Recruiting
Ambroxol study for Gaucher disease and Parkinson symptoms
This trial looks at ambroxol, a medicine, for people who have Gaucher disease and Parkinson disease that is linked to Gaucher. If you fit the condition group, the study may help doctors learn whether ambroxol can improve Parkinson-related symptoms in this specific situation.
Jerusalem, Please Select...Ages Up to 100 years - NCT02763683Recruiting
Study brain changes in Parkinson-related dementia
This study looks at brain features linked to dementia in people who have Parkinson disease. It may help researchers understand why dementia happens in Parkinson and how it could be detected or treated in the future.
St Louis, MissouriAges 50 years+ - NCT00001215Enrolling by invitation
Understanding Genetic Lysosomal Storage Disorders
This study aims to understand genetic factors in lysosomal storage disorders—rare conditions where the body cannot break down certain substances. Researchers will collect information from patients with these disorders, their family members, and healthy volunteers to learn how these diseases develop and affect people over time.
Bethesda, MarylandAges 1 week–110 years - NCT06687837RecruitingPhase 1
Stem cell therapy for Parkinson's disease
This trial tests whether implanting your own stem cells (made into dopamine-producing brain cells) can improve Parkinson's motor symptoms. You would need to be a candidate for brain surgery and have a stable medication routine.
Boston, MassachusettsAges 45–80 - NCT06080659Recruiting
Brain network study for Alzheimer's and Parkinson's
This study uses brain scans to look for patterns that might help diagnose memory or movement problems like Alzheimer's or Parkinson's disease. It compares people with mild symptoms, like forgetfulness or early Parkinson's, to healthy volunteers.
RennesAges 50–80 - NCT06145711Recruiting
Stem cell therapy for Parkinson's disease
This trial uses special stem cells (made from skin or blood cells) to replace damaged brain cells in people with Parkinson's. The goal is to see if these cells can improve movement and reduce symptoms.
Shanghai, Shanghai MunicipalityAges 30–70 - NCT06232772Recruiting
Biomarkers for early Parkinson's diagnosis
This study looks for new markers in the blood or other samples to help diagnose Parkinson's disease earlier. It compares people with Parkinson's, related conditions (like multiple system atrophy or progressive supranuclear palsy), and healthy volunteers to find differences.
Nanning, GuangxiAges 18–80 - NCT06814431Recruiting
Cancer risk in parkinson's patients with GBA gene mutation
This study looks at whether people with Parkinson's disease who have a specific gene change (GBA mutation) have a higher chance of developing cancer. It will help doctors understand the link between these conditions.
BrindisiAges 18 years+ - NCT04720365Recruiting
Home video game rehab to help Parkinson’s walking and balance
This trial tests whether a serious (therapeutic) home video-game program can improve walking and balance problems for people with Parkinson’s disease who still have trouble even with levodopa. It also looks at whether the approach is worth it in real-world care (cost and benefits).
BordeauxAges 18 years+ - NCT06586320Enrolling by invitation
Eye movement test for Parkinson's and Essential tremor
This study uses a simple eye movement test to see if it can help tell the difference between Parkinson's disease, Essential tremor, and healthy people. The goal is to find a better way to diagnose and track these conditions.
Manchester, New HampshireAges 18 years+ - NCT06008704Recruiting
PET scan study of pain in Parkinson's disease
This study uses a special brain scan (PET) to look at the serotonin system in people with Parkinson's who have chronic pain. The goal is to understand why some people feel pain and how the brain chemical serotonin might be involved.
Toulouse, Haute-GaronneAges 40–80
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Common questions
- Are there clinical trials for parkinson’s disease?
- Yes. Clin2 currently lists 723 recruiting parkinson’s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson’s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson’s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.