Clinical trials
Parkinson’s disease clinical trials
A movement disorder caused by the loss of dopamine-producing brain cells. We’re tracking 723 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04396873RecruitingPhase 1
PET brain scan study of inflammation markers in neurodegeneration
This Phase 1 study tests a PET scan to measure inflammation-related changes in the brain using a medication called ketoprofen. It may help researchers understand which people with certain brain diseases could benefit from treatments aimed at inflammation.
Bethesda, MarylandAges 18–99 - NCT04991831Recruiting
Registry study for Exablate thalamotomy in tremor-dominant Parkinson’s
This study follows people who are getting an Exablate procedure to treat medication-resistant, tremor-dominant Parkinson’s. It aims to track safety and outcomes in real-world care after the treatment is approved.
Miami, FloridaAges 30–99 - NCT06343558Recruiting
Gait and balance study for rare neurological diseases
This study looks at how people with rare or common neurological diseases walk and keep their balance. You will be asked to do simple walking and standing tasks to help doctors understand these problems better.
Milan, MilanAges 18–80 - NCT03233646Recruiting
Retina scans in memory and nerve disorders
This study uses pictures of the back of your eye (retinal imaging) to look for differences in people with neurodegenerative diseases and compares them with people without these conditions. It may help researchers understand eye changes that could connect to brain or nerve health.
Durham, North CarolinaAges 18 years+ - NCT07411664Enrolling by invitation
Balance and walking study for stroke, Parkinson's, or multiple sclerosis
This study uses special motion-tracking tools to measure balance and trunk control in people with first-time stroke, Parkinson’s, or multiple sclerosis. It aims to understand how these conditions affect stability, which could help tailor rehabilitation.
Kaposvár, Somogy CountyAges 18–80 - NCT06993142Recruiting
Slowing Parkinson's Early With Exercise
This trial tests whether a specific exercise program can slow the early stages of Parkinson's disease in people who have a genetic risk (LRRK2 or GBA variants). You will use a smartphone app to guide your exercise from home.
Rochester, New YorkAges 50 years+ - NCT07830654RecruitingPhase 2
Pet scan for Parkinson's disease
This study tests a new PET scan tracer called [18F]AV-133 to see if it can track Parkinson's disease over time. The scan may help doctors better understand the disease, and you would be part of the PPMI research program.
New Haven, ConnecticutAges 18 years+ - NCT06695455Recruiting
Can music help people with Parkinson's swallow better?
This trial tests if a rhythmic sound cue can reduce rolling (a swallowing problem) in people with Parkinson's. If you have trouble with solid foods but not severe liquid aspiration, you may qualify.
Saint-Sébastien-de-Morsent, NormandyAges 18 years+ - NCT07534397Recruiting
Brain stimulation for thinking and movement in Parkinson's
This study tests whether a gentle electrical current applied to the scalp can improve thinking, language, and movement problems in people with Parkinson's disease. You will receive either real or pretend stimulation to see if it helps.
Richardson, TexasAges 50–90 - NCT07207057RecruitingPhase 3
Platform trial testing multiple drugs for Parkinson's disease
This trial tests several experimental drugs at once to find new treatments for Parkinson's disease. If you have Parkinson's and take medication, you may be able to join and help speed up research.
LondonAges 30 years+ - NCT07187739Recruiting
Mediterranean diet for Parkinson's with deep brain stimulation
This study tests whether a Mediterranean diet can improve nutrition in people with Parkinson's disease who have had deep brain stimulation surgery. It may help you maintain better nutrition and overall health.
Ankara, AnkaraAges 45–64 - NCT07176494Recruiting
Revision of Deep Brain Stimulator in Parkinson's Disease
This study is for people with Parkinson's disease who need to have their deep brain stimulator (a device that sends electrical pulses to control movement) replaced or adjusted. The researchers want to learn the best way to do this procedure safely.
Ankara, Yenimahalle\AnkaraAges 40–85 - NCT06928519Recruiting
Entacapone with Madopar for early Parkinson's
This study tests whether adding entacapone to Madopar (a common Parkinson's medication) safely improves symptoms in people with early-stage Parkinson's. It aims to see if the combination works better than Madopar alone.
Nanning, GuanxiAges 18–80 - NCT06868160Recruiting
Brain stimulation to improve walking in Parkinson's disease
This study tests whether different types of gentle electrical stimulation on the scalp can help improve walking and balance problems in people with Parkinson's disease. The goal is to find a better way to support rehabilitation.
MilanAges 45–85 - NCT05347407Recruiting
Gut nerve cell biomarkers study for Parkinson’s risk
This trial studies nerve cell “biomarkers” from the gut to learn whether they can help detect Parkinson’s disease (or related conditions) earlier. You may be asked to undergo a colonoscopy to collect gut tissue for testing.
New York, New YorkAges 45–75 - NCT06875739Enrolling by invitation
Saliva test for early diagnosis of brain diseases
This study tests whether a saliva sample can help tell the difference between brain diseases like Alzheimer's, Parkinson's, and related conditions. By using a special laser technique, researchers hope to find a quick, non-invasive way to make an earlier and more accurate diagnosis.
CagliariAges 60–85 - NCT05066763Recruiting
Surveys for people with Parkinson’s and their care partners
This trial is for people with Parkinson’s disease, their care partners, and health professionals who work with people with Parkinson’s. The Parkinson’s Foundation will contact you to collect survey information and may invite you to future research opportunities.
Miami, FloridaAges 18 years+ - NCT06831500RecruitingPhase 1/Phase 2
Study on carbidopa/levodopa ratio for low blood pressure in MSA-P and Parkinson's
This study tests whether adjusting the ratio of carbidopa and levodopa (medications used for Parkinson's) can help reduce dizziness or fainting from low blood pressure when standing up, in people with Multiple System Atrophy (Parkinsonian type) or Parkinson's disease.
Lausanne, Canton of VaudAges Any age - NCT03457493RecruitingPhase 1/Phase 2
TSPO brain scan study in Parkinson’s disease
This trial looks at brain inflammation in people with Parkinson’s using a special PET scan. The goal is to understand how brain immune activity may relate to Parkinson’s, and how the scan results change over time.
Birmingham, AlabamaAges 30 years+ - NCT04706234Recruiting
Check swallowing and voice function in neurodegenerative diseases
This study looks at how well the throat and voice-related functions work in people with certain long-term brain or nerve conditions. It uses a specific throat exam during FEES to better understand swallowing and laryngopharyngeal (throat-area) function.
Innsbruck, TyrolAges 18 years+ - NCT07222605Enrolling by invitation
MemorEM device study for brain diseases
This study tests a device called MemorEM to see how it works for people with brain diseases that cause memory and thinking problems (like Alzheimer's, Parkinson's, and ALS). It aims to understand your experience with the device.
Atlanta, GeorgiaAges 45–100 - NCT07488351Recruiting
Self-kindness and confidence in Parkinson's: symptoms, function, quality of life
This study looks at how self-compassion and self-belief affect symptoms, daily function, and quality of life in people with Parkinson's disease. It aims to help researchers understand how emotional well-being relates to physical health.
Istanbul, TurkeyAges 40–85 - NCT07083089Recruiting
Hearing and thinking in early Alzheimer's and Parkinson's
This trial studies how hearing relates to early memory and movement problems in Alzheimer's and Parkinson's diseases. It may help find new ways to detect and track these conditions.
MontpellierAges 50–85 - NCT06949865Recruiting
AI-enhanced levodopa challenge test for parkinsonism
This study uses artificial intelligence (AI) to improve a standard test for parkinsonism called the levodopa challenge test. It may help doctors better understand how your movement symptoms respond to levodopa, a common Parkinson's medication.
BeijingAges 50–75
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Common questions
- Are there clinical trials for parkinson’s disease?
- Yes. Clin2 currently lists 723 recruiting parkinson’s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson’s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson’s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.