Clinical trials
Parkinson’s disease clinical trials
A movement disorder caused by the loss of dopamine-producing brain cells. We’re tracking 739 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07640555RecruitingEarly Phase 1
Brain imaging study for Parkinson's and related movement disorders
This research study tests a new type of brain scan (called a PET scan) that may help detect early signs of Parkinson's disease and similar conditions. You'll receive the scan and may have a spinal tap to check for specific protein markers.
New Haven, ConnecticutAges 50–80 - NCT07642908Recruiting
Brain imaging study of Parkinson's disease with LRRK2 gene mutations
This research study uses advanced MRI brain imaging to understand how a specific gene mutation (LRRK2) affects certain brain chemicals in people with Parkinson's disease. The goal is to learn more about how this genetic form of Parkinson's works, which could help develop better treatments.
Ann Arbor, MichiganAges 45 years+ - NCT07521384Enrolling by invitation
Real-World Study of Intranasal Cell Therapy for Brain Injuries
This study follows people who receive intranasal stem cell or exosome therapy (tiny packages from special cells) for brain or neurological conditions like stroke, brain injury, or cerebral palsy. Researchers track how well the treatment works by measuring inflammation markers in the blood and monitoring clinical improvements over time.
Monterrey, Nuevo LeónAges 4–80 - NCT07018388Enrolling by invitation
Comparing two brain targets for non-invasive stimulation in Parkinson's
This study compares two areas of the brain (subthalamic nucleus and globus pallidus interna) for stimulation using a new non-invasive technique called tTIS. The goal is to see which area works better to improve Parkinson's symptoms.
Shanghai, Shanghai MunicipalityAges 50–85 - NCT06973018Enrolling by invitation
Online cognitive rehab for mild memory problems
This trial tests an online program to help people with mild to moderate cognitive problems after a brain injury or nervous system disease improve their thinking skills. It is for Swedish speakers with internet access.
Stockholm, Stockholm CountyAges 18 years+ - NCT06932185Enrolling by invitation
Ultrasound brain stimulation for movement disorders
This study tests if low-intensity ultrasound can safely change brain activity patterns in people with movement disorders like Parkinson's. You may be eligible if you already have a special brain implant that can record brain signals.
OxfordAges 18 years+ - NCT06837038Enrolling by invitation
Rhythmic beats to improve walking after stroke or Parkinson's
This trial tests whether listening to rhythmic music while walking can improve gait problems caused by stroke, Parkinson's disease, or other parkinsonism conditions. It is designed for people who can walk on their own but have an uneven or slow pace.
Beijing, Beijing MunicipalityAges 50–80 - NCT06827158Enrolling by invitation
Turkish manual dexterity questionnaire for Parkinson's
This study is testing a new Turkish questionnaire about how Parkinson's affects hand and finger movements (manual dexterity). If you have Parkinson's and are between 40 and 80, you may be able to help researchers see if the questionnaire is a reliable tool for Turkish speakers.
Bandırma, BalıkesirAges 40–80 - NCT06671626Enrolling by invitation
Brain recordings during DBS surgery for Parkinson's
This study records brain activity during deep brain stimulation (DBS) surgery for Parkinson's disease to better understand how the brain controls actions. It might help improve future treatments.
Dallas, TexasAges 18 years+ - NCT05967390Enrolling by invitation
Personalized brain-mapping test using a scalp-to-brain scan
This trial looks at whether a personalized brain “map” using imaging and scalp measurements can be measured and evaluated in people who can safely attend the testing. It may help researchers better understand how brain structure relates to performance, using scan-based measurements and related procedures.
Hong KongAges 60–95 - NCT05919160Enrolling by invitation
New tiny electrode to record brain activity during DBS
This study tests a high-density microelectrode that captures detailed brain recordings while surgeons place a deep brain stimulator for Parkinson’s disease. It may help doctors better locate the exact brain area to target during surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT05826457Enrolling by invitation
Study for early RBD as a possible Parkinson’s risk
This study looks at people with REM sleep behavior disorder (RBD), confirmed by a sleep test, who may be in the early “prodromal” stage before Parkinson’s or related diseases. It also enrolls healthy controls to compare results from brain and body testing to better understand who is at risk.
Los Angeles, CaliforniaAges 18 years+ - NCT05450237Enrolling by invitation
Testing thinking and memory questionnaires in people with brain injury
This study checks how well certain questionnaire and testing tools work for people who have brain damage from neurologic conditions and ongoing brain inflammation. It may help future patients by improving which tests are most accurate and easy to use.
Pozzilli, IserniaAges 18–80 - NCT04680130Enrolling by invitation
Study of brain, genetics, and clinical symptoms in neurodegenerative illness
This study looks at how your symptoms, brain imaging (MRI), and genetic factors relate to neurodegenerative conditions. It may help researchers better understand what causes these illnesses and how to classify them.
Rochester, MinnesotaAges 21 years+ - NCT04605263Enrolling by invitation
Deep brain stimulation for Parkinson’s walking and falls
This study tests a brain surgery treatment (deep brain stimulation) to help improve gait problems such as freezing of walking, gait instability, or falls in people with Parkinson’s disease. It may help people whose walking symptoms are not well controlled by levodopa (a common Parkinson’s medicine).
Phoenix, ArizonaAges 18–75 - NCT03815656Enrolling by invitation
Closed-loop deep brain stimulation for Parkinson’s medication side effects
This study tests a “smart,” closed-loop deep brain stimulation (DBS) system that adjusts stimulation based on your brain signals. It’s designed for people with Parkinson’s who get troubling medication side effects, with the hope of improving symptoms more smoothly.
Durham, North CarolinaAges 18–75 - NCT05370079Recruiting
Control group for people with specific serious illnesses
This trial includes a “control” group of people with certain diseases to compare outcomes against another group. If you qualify, you may receive the standard approach used in usual care rather than the experimental treatment.
BronAges 18 years+ - NCT07533799Recruiting
Swedish BioFINDER Sleep Study: Brain imaging in RBD and Parkinson's
This study examines brain changes in people with REM sleep behavior disorder (acting out dreams during sleep) and early Parkinson's disease using brain imaging scans. Researchers want to understand how sleep problems relate to Parkinson's development and find early warning signs.
MalmöAges 50–100 - NCT07777484RecruitingPhase 1
Study of TRB-001 vaccine for Parkinson's disease after prior immunotherapy
This study tests an experimental vaccine called TRB-001 in people with Parkinson's disease who have already received a previous immunotherapy targeting alpha-synuclein. The goal is to see if the vaccine is safe and how it affects the immune system and the disease.
ViennaAges 18 years+ - NCT07115394Recruiting
Brain wave tracking during DBS for movement disorders
This study uses EEG (a non-invasive scalp recording) to measure brain signals while deep brain stimulation (DBS) is active. It aims to better understand how DBS affects brain activity in people with Parkinson's disease, essential tremor, or dystonia.
HamburgAges 35–85 - NCT05698810Recruiting
Study exams practice for upcoming research
This trial checks whether it’s practical and workable to set up study-related exams before planned research. It mainly recruits adults who can consent and be contacted, so the team can prepare future studies smoothly.
GrenobleAges 18 years+ - NCT07195825RecruitingPhase 1
Gene therapy BBM-P002 for Parkinson's disease safety trial
This trial tests a new gene therapy called BBM-P002 for Parkinson's disease. It aims to see if the treatment is safe and tolerable, and may help people with moderate to advanced Parkinson's who have had the condition for at least 5 years.
Shanghai, Shanghai MunicipalityAges 40–70 - NCT06685510Enrolling by invitation
Deep brain stimulation outcomes and electrode position in Parkinson's
This study looks at how the placement of electrodes during deep brain stimulation (DBS) for Parkinson's disease affects recovery and motor symptoms right after surgery. It could help doctors improve DBS outcomes for people with Parkinson's.
Nanchang, JiangxiAges 18–75 - NCT07378813Recruiting
Light vs. heavy weight training for Parkinson's disease
This study compares two types of weight training (lifting lighter weights versus heavier weights) in people with Parkinson's disease. It aims to see which approach best improves movement, strength, and daily function.
Coral Gables, FloridaAges 50–85
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Common questions
- Are there clinical trials for parkinson’s disease?
- Yes. Clin2 currently lists 739 recruiting parkinson’s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson’s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson’s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.