Clinical trials
Parkinson’s disease clinical trials
A movement disorder caused by the loss of dopamine-producing brain cells. We’re tracking 739 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07145190Recruiting
Starting Sublingual Apomorphine for Parkinson's OFF Episodes
This study looks at how patients start and adjust a new medicine (sublingual apomorphine, or SL-APO) for Parkinson's disease OFF episodes. OFF episodes are times when Parkinson's symptoms come back between medicine doses. If you are about to start SL-APO for the first time, this trial may be a good fit.
BerlinAges 18 years+ - NCT07172295Recruiting
Low-intensity focused ultrasound for hand tremor
This study uses low-intensity focused ultrasound to stimulate a deep brain area and reduce hand tremors. It is for people with Parkinson's disease, essential tremor, or dystonic tremor whose medications don't work well enough.
Hsinchu, Hsinchu CityAges 18–80 - NCT07193355Recruiting
Motor imagery training for Parkinson's disease
This trial tests if thinking about movements (motor imagery) can help improve hand function in people with Parkinson's disease. It may offer a non-drug way to manage symptoms.
Kahramanmaraş, OnikişubatAges 40–75 - NCT07219927Recruiting
Patient experiences with pump-delivered Parkinson's drug
This study looks at real-world experiences of people with Parkinson's who are using ONAPGO, a medication given continuously under the skin through a pump. The goal is to understand how this treatment works in daily life.
Aliso Viejo, CaliforniaAges 18 years+ - NCT07257861Recruiting
Apomorphine Pump for Late-Stage Parkinson's at End of Life
This trial studies whether a continuous apomorphine pump can help people with advanced Parkinson's disease who can no longer take oral medications and are receiving palliative care. The pump delivers medicine under the skin to manage symptoms when other treatments are no longer possible.
CrestAges 18 years+ - NCT07284290RecruitingPhase 4
Brain imaging, thinking, and medication study for Lewy body dementia
This study looks at how brain changes affect attention and thinking in people with Lewy body dementia. It includes brain scans, an EEG, and a medication option to see if it helps with symptoms.
Richmond, VirginiaAges 50–89 - NCT07291687Recruiting
Test of tDCS for improving walking
This study tests whether a safe, non-invasive brain stimulation (tDCS) can improve movement and walking in people who have trouble with motor function. You can join if you're able to walk daily, with or without a walking aid, and don't have metal in your brain.
Toronto, OntarioAges Any age - NCT07176286RecruitingPhase 2
PET scan study for diagnosing Lewy body dementia
This trial is testing a special PET scan that uses a radioactive tracer (18F-mFBG) to see how much it is taken up by the heart. The goal is to help tell Lewy body disease (Parkinson's or Lewy body dementia) apart from other brain disorders.
Houston, TexasAges 18 years+ - NCT07355842Recruiting
Can slow brain waves slow Parkinson's?
This study tests whether playing soft sounds during deep sleep can slow down brain changes in people with REM sleep behavior disorder (a condition linked to Parkinson's disease). It is for people who have this sleep disorder or were recently diagnosed with Parkinson's, and are not yet on Parkinson's medications.
Zurich, Canton of ZurichAges Any age - NCT07360886Recruiting
Early detection of brain conditions in active drivers
This study looks at how well doctors can spot early signs of certain brain conditions in people who drive. You may join if you have a valid license, are between 18 and 85, and have one of the neurological diagnoses the study is focusing on.
Olomouc, Olomouc RegionAges 18–85 - NCT07382674Recruiting
Exercise program for older adults with Parkinson's
This trial tests a fun exercise system designed for older adults with mild to moderate Parkinson's disease. It aims to help improve movement and well-being through engaging physical activities.
Atlanta, GeorgiaAges 40 years+ - NCT07384143Recruiting
Robotic arm rehab for cognitive recovery after stroke
This study tests whether robot-assisted arm exercises can help people recover both arm movement and thinking skills. It may be an option if you have arm weakness after a stroke or other neurological condition.
Messina, MaineAges 18–75 - NCT02060695Recruiting
Study links Parkinson symptom ups and downs over time
This study looks at how changes in movement symptoms and non-movement symptoms happen together in people with early Parkinson disease. It may help doctors better understand what triggers symptom “ups and downs” and how to time treatment or monitoring.
SeoulAges Any age - NCT02897063RecruitingPhase 1
Test medicines for low blood pressure in nerve-related disorders
This early (Phase 1) study tests whether midodrine and droxidopa can improve blood-flow pooling in the belly in people with nerve problems that affect blood pressure when standing. It’s looking at safety and how the body responds, which may help reduce dizziness or fainting for some participants.
Nashville, TennesseeAges 40–80 - NCT03371407Recruiting
Study brain movement training in people with Parkinson’s
This study looks at how people with Parkinson’s adapt their movements and how their brain sensorimotor system works. It may help researchers improve understanding of Parkinson’s and refine movement-focused therapies.
MarseilleAges 18 years+ - NCT02553525Enrolling by invitation
Testing different stimulation patterns in Parkinson’s, tremor, and MS
This study tests whether changing the “stimulation pattern” in a deep brain stimulator can improve how well symptoms are controlled. If you are already getting (or replacing) a deep brain stimulator, this may help fine-tune the settings for you.
Gainesville, FloridaAges 21–80 - NCT01734122Recruiting
Focused radiation for essential or Parkinson tremor
This trial tests whether precisely targeted radiation to the brain can reduce tremors in people whose symptoms are not controlled enough by medication. It may help those who prefer radiation over deep brain surgery options.
Nashville, TennesseeAges 18 years+ - NCT07399496Recruiting
Fast TMS for apathy in Parkinson's disease
This study tests a faster version of TMS (transcranial magnetic stimulation) to see if it can help with apathy—low motivation and lack of interest—in people with Parkinson's disease. You will receive several TMS sessions each day over a short period, and the study team will check if your mood and motivation improve.
Charleston, South CarolinaAges 45–85 - NCT07400731Recruiting
Ear stimulation for Parkinson's symptoms
This study tests whether a device that stimulates the ear can improve Parkinson's symptoms during 'off' periods, when medication wears off. It compares how you feel before and after ear stimulation.
IstanbulAges 44 years+ - NCT07410598Recruiting
Testing a new way to use deep brain stimulation at home
This study tests a new type of brain stimulation called patterned stimulation for people with Parkinson's who already have a deep brain stimulation (DBS) device. It aims to see if using this special stimulation at home is safe and comfortable.
Gainesville, FloridaAges 18–80 - NCT07424365Recruiting
Vagus nerve stimulation for thinking skills in health and Parkinson's
This study explores whether vagus nerve stimulation (a gentle electrical pulse that travels through a nerve in your ear) can boost thinking and decision-making skills in healthy people and those with Parkinson's disease. It involves a noninvasive device that stimulates the ear, and you may participate if you meet certain health criteria.
Aurora, ColoradoAges 18–65 - NCT07519096Recruiting
Home-Based Fall Prevention Program for Parkinson's Disease
This study tests a fall prevention program designed for people with Parkinson's disease and their care partners. It aims to help reduce falls and improve balance and safety at home.
Beachwood, OhioAges 18 years+ - NCT07580612Recruiting
Home-based AI system for detecting freezing of gait in Parkinson's
This study tests an artificial intelligence system that detects freezing of gait—sudden, involuntary pauses while walking—using sensors you wear at home. The goal is to better understand and eventually help manage this common Parkinson's symptom.
LeuvenAges 18 years+ - NCT07635823Recruiting
Adaptive deep brain stimulation for Parkinson's disease
This study tests a new type of deep brain stimulation (DBS)—a surgical treatment that uses electrical pulses to help control Parkinson's symptoms. Unlike standard DBS, this system adapts automatically to your body's needs. You may qualify if you've never had DBS surgery or if you've had it before and are willing to switch to the new device.
Hefei, AnhuiAges 18 years+
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Common questions
- Are there clinical trials for parkinson’s disease?
- Yes. Clin2 currently lists 739 recruiting parkinson’s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson’s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson’s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.