Clinical trials
Parkinson’s disease clinical trials
A movement disorder caused by the loss of dopamine-producing brain cells. We’re tracking 723 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06582355Recruiting
Brain training with MRI for Parkinson's disease
This study tests whether a brain-training technique called neurofeedback can help people with Parkinson's disease. You will learn to control certain brain signals while having an MRI scan, which may improve your symptoms.
CologneAges 18 years+ - NCT07271927Recruiting
Light therapy for Parkinson's motor and thinking changes
This study tests whether shining light on the whole body (photobiomodulation) can help with movement and thinking problems in Parkinson's disease. It is for people in early to moderate stages who can walk independently.
Yangsan, Gyeongsangnam-doAges 40 years+ - NCT07277205Recruiting
Balance and thinking exercises for Parkinson's disease
This study compares two types of rehabilitation exercises for people with Parkinson's disease: one focusing on balance (vestibular) and one combining balance with thinking tasks (dual-task). It aims to see which is better at improving balance and daily function. If you are between 40 and 75, have mild to moderate Parkinson's, and can do cognitive tasks, you might be eligible.
Istanbul, MaltepeAges 40–75 - NCT06892717Recruiting
Caregiver burden in Parkinson's disease study
This study looks at how caring for someone with Parkinson's disease affects the caregiver. It aims to understand the challenges and needs of family members or friends who provide unpaid care.
Istanbul, BeylikdüzüAges 40–80 - NCT07250672Recruiting
3D video training for Parkinson's movement
This trial tests if watching personalized 3D videos of movements can help improve walking and other skills in people with Parkinson's. It involves using a special viewer to watch actions that match your own needs.
Bolu, BoluAges 50–85 - NCT06485986Recruiting
Brain Networks in Parkinson's and DBS
This study uses a brain scan called MEG to look at how Parkinson's disease and impulse control disorders affect brain networks in people who have already had deep brain stimulation (DBS) surgery. You will be asked to delay your morning medication so the researchers can study your brain without the effects of the drugs.
OxfordAges 18 years+ - NCT06388863Recruiting
Fecal transplant for constipation in Parkinson's disease
This study tests whether a treatment called fecal microbiota transplantation (FMT) can help relieve constipation in people with Parkinson's disease. FMT uses healthy donor stool to improve gut bacteria, which may ease constipation and possibly improve Parkinson's symptoms.
Shanghai, Shanghai MunicipalityAges 40–75 - NCT06906679Recruiting
Upper limb rehab for Parkinson's disease
This trial tests an upper limb rehabilitation program for people with Parkinson's disease. It aims to improve arm and hand function while on regular medication.
Cassino, FRAges 30–80 - NCT06901869Recruiting
Physical activity study for Parkinson's disease
This study explores how physical activity affects people with Parkinson's disease. It's open to anyone with mild to severe Parkinson's who wants to be more active.
Stockholm, SolnaAges Any age - NCT07227896Recruiting
Study of a new pump treatment for advanced Parkinson's
This study looks at a new pump treatment (foslevodopa/foscarbidopa) for people with advanced Parkinson's who are having motor fluctuations. It aims to see if it improves quality of life when started earlier in the advanced stage.
Georgetown, TexasAges 18–80 - NCT06916260Recruiting
Light therapy study for people with Parkinson's disease
This study tests whether light therapy can help people with Parkinson's disease. Participants will receive light therapy sessions and have their symptoms checked before, after, and three months later.
Newark, DelawareAges 50–80 - NCT07213856Recruiting
Dietary help for constipation in Parkinson's disease
This study tests whether a special diet can help improve constipation symptoms in people with early-stage Parkinson's disease. It aims to see if changing what you eat can make bowel movements more regular and comfortable.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06893055Recruiting
Strength and endurance training for Parkinson's
This study tests a circuit training program that combines strength and endurance exercises to see if it helps people with Parkinson's disease improve their movement and daily function.
Prague, PragueAges 18–75 - NCT06573762Recruiting
Home monitoring for Parkinson's disease
This study uses a Fitbit to track movement and symptoms from home. It is for people who are newly referred or recently diagnosed with Parkinson's disease.
Iowa City, IowaAges 50–110 - NCT07207122Recruiting
Focused ultrasound for Parkinson's cognitive symptoms
This trial tests whether a non-invasive ultrasound treatment, called transcranial focused ultrasound stimulation (tFUS), can improve movement and thinking in people with Parkinson's disease. It may be an option for those whose symptoms are not well controlled by medication alone.
Tucson, ArizonaAges 22–80 - NCT07175922Recruiting
A study of gene changes in people with Parkinson's disease
This study looks at how the csgA gene changes over time in people with Parkinson's disease, especially if they have stomach or bowel issues. It aims to help understand how these changes might relate to symptoms.
LeidenAges 18–80 - NCT07166757RecruitingPhase 1/Phase 2
Study of XS411 for early-onset Parkinson's disease
This trial tests a new treatment called XS411 for people with early-onset Parkinson's disease (age 50 or younger at diagnosis). It is for those whose motor symptoms are not well controlled with standard medications and who may benefit from a neurosurgical procedure.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07157345RecruitingPhase 1
Testing PDR-001 for Parkinson's Disease
This trial tests a new drug, PDR-001, to see if it can safely remove harmful proteins from the brain in people with early Parkinson's disease. It may help slow down the disease.
Shanghai, Shanghai MunicipalityAges 40–65 - NCT07157735RecruitingPhase 2
Testing an anti-inflammatory drug for early Parkinson's disease
This trial tests whether the anti-inflammatory drug dapansutrile can help people with early Parkinson's disease. You would get either dapansutrile or a placebo (a pill with no active drug) to see if it slows the disease.
CambridgeAges 50–80 - NCT06955377Recruiting
Bending forward and airway protection in Parkinson's disease
This study looks at how bending forward (trunk flexion) affects your body's ability to protect your airway in Parkinson's disease. It may help understand breathing risks and guide therapy.
PragueAges 18 years+ - NCT07151378RecruitingPhase 3
Intestinal gel for Parkinson's mood and behavior problems
This trial tests a gel form of levodopa (called Lecigon) given through a tube into the intestine to see if it helps reduce mood swings, impulsive behaviors, and other mental side effects in people with Parkinson's who already have motor fluctuations. It is for people who have had Parkinson's for at least 5 years and are between 18 and 75 years old.
Saarlouis, SaarlandAges 18–75 - NCT06732180RecruitingPhase 1
Testing a new drug (GT-02287) for Parkinson's disease
This trial tests an investigational drug called GT-02287 in people with early-stage Parkinson's disease (diagnosed within the last 7 years). The goal is to see if it is safe and how the body processes it, with a special focus on people with certain genetic changes (GBA1 mutations) that may be linked to Parkinson's.
Darlinghurst, New South WalesAges 30–85 - NCT07118956Recruiting
Ear stimulation for apathy in Parkinson's
This trial tests whether a gentle electrical stimulation on your ear (taVNS) can help improve low motivation (apathy) in people with Parkinson's. It also uses MRI scans to see how the treatment affects the brain.
Hefei, AnhuiAges 40–90 - NCT07110376Recruiting
Brain recordings during sleep with deep brain stimulation for Parkinson's
This study looks at brain activity during sleep in people with Parkinson's who have a deep brain stimulation (DBS) device. It aims to understand how different DBS settings affect sleep, which may help improve treatment.
Cleveland, OhioAges 18 years+
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Common questions
- Are there clinical trials for parkinson’s disease?
- Yes. Clin2 currently lists 723 recruiting parkinson’s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson’s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson’s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.