Clinical trials
Participation clinical trials
Below are recruiting participation clinical trials, each written for real people, not researchers. We’re tracking 2,290 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07448610RecruitingPhase 4
Real-world safety and effectiveness of gene therapy for spinal muscular atrophy
This study tracks how well the gene therapy ITVISMA works in everyday medical practice for people with spinal muscular atrophy (SMA). It aims to see if the treatment is safe and effective in a real-world setting.
New York, New YorkAges 2–100 - NCT07449702RecruitingPhase 2
Long-term safety study of ORKA-001 for plaque psoriasis
This study is a continuation for people who already took ORKA-001 for plaque psoriasis and did well. It tests whether staying on the medicine keeps helping without any new safety concerns.
Phoenix, ArizonaAges 18 years+ - NCT07446855RecruitingPhase 1/Phase 2
Study of AZD4956 for advanced solid tumors with DNA repair problems
This trial tests a new drug called AZD4956, alone or with other cancer medicines, for people with advanced solid tumors that have certain DNA repair problems (called homologous recombination deficiency). It may be an option if you have breast, ovarian, prostate, or pancreatic cancer with a specific gene change, and you have or haven't had previous PARP inhibitor treatment.
New York, New YorkAges 18–130 - NCT07446101RecruitingPhase 1
Testing mirikizumab in healthy volunteers
This study is testing a new medicine called mirikizumab in healthy people to see how it works in the body. Healthy volunteers help researchers understand the drug's safety before it is studied in patients with a disease.
Daytona Beach, FloridaAges 18–65 - NCT07448038RecruitingPhase 2
Study of an anti-inflammatory pill for heart artery health
This trial tests a pill that may reduce inflammation in blood vessels, which could lower the risk of heart attacks or strokes in people with atherosclerosis. It could help if you have plaque in your arteries and are at risk for major heart events.
Beverly Hills, CaliforniaAges 18 years+ - NCT07444814RecruitingPhase 1
HWK-007 for advanced solid tumors
This trial tests a new drug called HWK-007, which is designed to target and attack cancer cells while sparing healthy ones. It is for people with specific advanced solid tumors (lung, endometrial, or ovarian cancer) that have not responded well to standard treatments.
Little Rock, ArkansasAges 18 years+ - NCT07449741RecruitingPhase 1
Early safety test of HXN6005 in healthy adults
This early-phase study tests an experimental drug called HXN6005 in healthy adults to see how safe it is and how the body handles it. It's looking for volunteers who are generally healthy and meet basic age and weight requirements.
Bayswater, VictoriaAges 18–55 - NCT07452198RecruitingPhase 3
Study of new drug for relapsed or hard-to-treat multiple myeloma
This trial tests a new medicine (GR1803) against a standard combination treatment for people whose multiple myeloma has come back or stopped responding to prior therapies. It aims to see if the new drug works better.
TianjinAges 18 years+ - NCT07441694RecruitingPhase 1
Study of INCA036978 for blood cancers
This trial tests a new drug called INCA036978 for people with a group of blood cancers called myeloproliferative neoplasms (MPNs), including myelofibrosis, polycythemia vera, and essential thrombocythemia. It aims to see if the drug is safe and works well.
Birmingham, AlabamaAges 18 years+ - NCT07439263RecruitingPhase 1
First test of HB2198 in healthy adults
This study tests a single dose of an experimental therapy (HB2198) in healthy volunteers to see how the body handles it. It is a first-in-human trial designed to check safety and how the drug affects your immune system.
Bayswater, VictoriaAges Up to 55 years - NCT07439796RecruitingPhase 1
Study of ORN252 in healthy volunteers
This trial tests a new medicine called ORN252 in healthy people to see how safe it is. It helps researchers understand how the drug works before testing it in patients.
Herston, QueenslandAges 18–55 - NCT07444567RecruitingPhase 3
Continuing benralizumab treatment after a previous study
This trial lets people who completed an earlier benralizumab study and are benefiting from the medicine keep receiving it. The goal is to provide ongoing access while we continue to monitor safety and effectiveness.
Aurora, ColoradoAges 6 years+ - NCT07438782RecruitingPhase 1
Investigational drug for advanced solid tumors
This study tests an investigational drug, GSK5533524, either alone or with other treatments, in adults with advanced solid tumors that have stopped responding to standard therapies. The goal is to find a safe dose and see if it helps shrink or control the tumor.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07441395RecruitingPhase 2
Study of soquelitinib for moderate to severe eczema
This trial tests an experimental pill called soquelitinib for people with moderate to severe eczema (atopic dermatitis). It aims to see if the drug can reduce symptoms like itching and skin inflammation.
South San Francisco, CaliforniaAges 18 years+ - NCT07438405RecruitingPhase 2
Long-term safety study of AMG 732 for thyroid eye disease
This trial tests the long-term safety and effectiveness of AMG 732 for people with moderate-to-severe thyroid eye disease who have already completed an Amgen study of this drug. It allows continued treatment without needing immediate eye surgery.
Little Rock, ArkansasAges 18–99 - NCT07444281RecruitingPhase 1
CAR T-cell therapy for GPC3-positive advanced lung cancer
This trial tests a new type of immunotherapy called CAR T-cells (C-CAR031) for people with advanced squamous cell lung cancer that has a specific marker called GPC3. The treatment involves collecting your own immune cells, modifying them to attack cancer, and infusing them back into your body.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07437105RecruitingPhase 1
Healthy volunteer study of VX-272 safety
This study tests a new investigational medicine called VX-272 in healthy volunteers. Researchers want to check its safety and how it moves through the body, so you would not have the condition the medicine is being developed for.
Tempe, ArizonaAges 18–55 - NCT07441642RecruitingPhase 2
Study of FWY003 for geographic atrophy in age-related macular degeneration
This trial tests an investigational drug FWY003 against a placebo to see if it can slow or stop the progression of geographic atrophy, a form of advanced age-related macular degeneration that causes vision loss.
Huntington Beach, CaliforniaAges 50 years+ - NCT07444476RecruitingPhase 3
Study of salanersen for spinal muscular atrophy (ages 15-60)
This trial tests a medicine called salanersen (BIIB115) to see how well it improves movement and how safe it is in people with spinal muscular atrophy (SMA). It includes those who have never taken an SMA drug or are currently on risdiplam and willing to switch.
Palo Alto, CaliforniaAges 15–60 - NCT07436260Recruiting
Comparing milk types and plant drink for metabolic health
This study compares the effects of two types of cow's milk (A2A2 and A1A2) and a plant-based drink on your metabolism (how your body uses energy). It may help you understand which milk option is better for your health.
Warsaw, Masovian VoivodeshipAges 30–60 - NCT07435831Recruiting
Kimchi and gut health study
This trial tests whether eating kimchi every day for 3 weeks can improve gut health in people who are overweight. You'll be asked to eat study food daily and follow the study plan.
Davis, CaliforniaAges 19–70 - NCT07432880Recruiting
Study of children with severe MMA linked to the MMUT gene
This study is for children up to 16 years old with a severe form of methylmalonic acidemia (MMA) caused by a specific gene change (MMUT). It aims to better understand the disease and may lead to future treatments. Both children who have had a liver transplant and those who have not can join, as long as certain criteria are met.
Philadelphia, PennsylvaniaAges Up to 16 years - NCT07433179RecruitingPhase 1
Testing SEP-479 in healthy adults
This trial tests a new medication called SEP-479 in healthy volunteers to see how the body handles it. Volunteers receive either a single dose or multiple doses of the drug as part of early safety research.
MelbourneAges 21–60 - NCT07426757RecruitingPhase 1
A study of PF-07994525 for advanced multiple myeloma
This trial tests an experimental drug, PF-07994525, for people with advanced multiple myeloma that has not responded to or could not tolerate at least 3 prior treatments. The goal is to see if it can help control the cancer.
Denver, ColoradoAges 18 years+
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Common questions
- Are there clinical trials for participation?
- Yes. Clin2 currently lists 2,290 recruiting participation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a participation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a participation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.