Clinical trials
Pathogenesis clinical trials
Below are recruiting pathogenesis clinical trials, each written for real people, not researchers. We’re tracking 46 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06967558RecruitingPhase 2
GLP-1 hormone role in prediabetes
This study looks at how a hormone called GLP-1, made in the pancreas, affects blood sugar levels in people with borderline high blood sugar (prediabetes). It may help find new ways to prevent diabetes.
Rochester, MinnesotaAges 25–70 - NCT06996327Recruiting
How ultra-processed foods affect eczema in children
This study looks at whether compounds from ultra-processed foods (like packaged snacks and sodas) contribute to eczema (atopic dermatitis) in children. Researchers will compare children with eczema to healthy children of the same age and sex.
NaplesAges 6 months–10 years - NCT07000786Recruiting
Endometriosis study exploring causes of the condition
This study looks at what causes endometriosis by comparing healthy people and those with a clear diagnosis. You may join if you have regular periods and haven't used hormonal treatments in the last 3 months.
BrusselsAges 18–56 - NCT07040332Recruiting
Understanding allergic bronchopulmonary aspergillosis
This study looks at why some people with asthma get a lung infection from mold called aspergillus. It will help doctors better understand the condition and how to treat it.
Jinan, ShandongAges 18 years+ - NCT07102030Recruiting
Understanding lupus subgroups to improve treatment
This study is trying to better understand lupus (SLE) by looking at different types of the disease. It may help doctors find more personalized treatments in the future.
StockholmAges 18–100 - NCT07207486Recruiting
Studying cholesterol's role in memory and thinking decline
This study looks at how cholesterol and related substances in the body may be linked to the development and progression of certain dementias. It aims to find better ways to understand and track these diseases.
Torino, toAges 40–85 - NCT07258784Recruiting
Studying windpipe tissue to understand non-cancerous narrowing
This study uses a small piece of tissue from your windpipe to look at the genes and cells that cause benign (non-cancerous) tracheal stenosis. It aims to understand why the narrowing happens, which could lead to better treatments.
Baltimore, MarylandAges 18–80 - NCT07314762Recruiting
Support for elderly patients before, during, and after surgery
This trial looks at how to better care for older adults (65+) who are having surgery. It aims to improve their experience and recovery during the time leading up to, during, and after their procedure.
Wenzhou, ZhejiangAges 65 years+ - NCT00669266Recruiting
Study of adrenal tumors—causes and possible treatments
This study looks at adrenal tumors found on imaging (scans) to better understand what causes them and how they might be treated. If you have an adrenal tumor on a scan, this trial may be looking to enroll you for that purpose.
WürzburgAges Up to 100 years - NCT00001281Recruiting
Understanding how HIV affects blood cells and body fluids
This research study examines how HIV works in the blood and body fluids of people with and without HIV. By studying blood samples, researchers hope to better understand HIV infection and develop better treatments.
Washington D.C., District of ColumbiaAges 18–120 - NCT01778543Recruiting
Study genes behind small eyes and eye coloboma
This study looks at how genes may cause certain eye conditions called microphthalmia, anophthalmia, and uveal coloboma. You may qualify if you have one of these conditions or are a close, unaffected relative who could also carry the gene.
Bethesda, MarylandAges 1–100 - NCT00867269Recruiting
Study of causes and progression of low CD4 blood cells
This study looks for what causes and how idiopathic low CD4 cells happen over time, using blood and tissue samples. It may help doctors learn why this occurs and how to better track people with it.
Bethesda, MarylandAges 18 years+ - NCT02190266Recruiting
Study genetics and cause of hard-to-treat Valley fever
This study looks at why “Valley fever” is difficult to treat or has spread beyond the lungs, and how a person’s genetics may be involved. You may be asked for blood or other samples for genetic testing and for storing samples for future research.
Bethesda, MarylandAges 2–100 - NCT02504879Recruiting
Study of melorheostosis progression and genetic causes
This study follows adults with suspected or confirmed melorheostosis to understand how the condition develops and what outcomes to expect. It may help researchers better understand the disease and its genetic factors.
Bethesda, MarylandAges 18–90 - NCT05851209Recruiting
Study biomarkers in people with moderate aortic valve narrowing
This study looks at blood and/or body signals (called biomarkers) to understand why aortic valve narrowing may worsen and what outcomes people have. You may be able to help researchers by undergoing regular heart care plus additional testing like MRI or CT if you qualify.
BonnAges 18 years+ - NCT00807482Recruiting
Study of lung disease causes in primary ciliary dyskinesia
This study looks at how primary ciliary dyskinesia (PCD—a lifelong problem with tiny lung “sweepers”) affects the lungs. You may be able to join if you strongly seem to have PCD based on symptoms, or if you’re a healthy person with a close family member who has confirmed PCD.
Chapel Hill, North CarolinaAges Any age - NCT01728402Enrolling by invitation
Study of the causes of certain blood cancers
This study looks at what leads to specific blood cancers and related blood disorders. If you have one of the listed conditions (or are being evaluated for it), you may be asked to join research that helps doctors understand why these illnesses happen.
Portland, OregonAges 1 year+ - NCT07415837Recruiting
Studying a molecule in muscle diseases and healthy people
This study looks at a molecule called miR-1 in the blood to see if it can help understand muscle diseases. Researchers will compare levels in people with certain muscle conditions and in healthy volunteers.
Clermont-FerrandAges 2 years+ - NCT07519837Recruiting
Understanding Cancer Wasting in Digestive Cancers
This study explores why certain cancers cause patients to lose weight and muscle (called cancer cachexia) and tests ways to reverse it. Researchers will study tissue samples from patients with cancers of the food pipe, liver, stomach, or bile ducts to understand what's happening at a cellular level.
Shenyang, LiaoningAges 18 years+ - NCT07539675Recruiting
Eye protein changes in angle-closure glaucoma
This study examines how proteins in the eye lens support structures change in patients with angle-closure glaucoma. Researchers will compare these proteins in people with glaucoma who have loose or normal support structures during surgery, and in people without glaucoma having cataract surgery.
Wuhan, HubeiAges 50 years+ - NCT07563608Recruiting
Understanding High Blood Pressure in the Lungs for Dialysis Patients
This study investigates why some dialysis patients develop high blood pressure in their lung blood vessels and how it affects their health. Researchers will assess heart function and follow patients over time to better understand this condition.
Pavia, LombardyAges 18–75 - NCT07604467Recruiting
Understanding Stem Cells in Takotsubo Heart Syndrome
This study examines how certain stem cells (CD34+ cells) may contribute to takotsubo syndrome, a temporary heart condition often triggered by stress. By understanding this connection, researchers hope to improve treatment and recovery for patients with this condition.
Ljubljana, LjubljanaAges 18 years+
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Common questions
- Are there clinical trials for pathogenesis?
- Yes. Clin2 currently lists 46 recruiting pathogenesis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pathogenesis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pathogenesis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.