Clinical trials
Pathogenesis clinical trials
Below are recruiting pathogenesis clinical trials, each written for real people, not researchers. We’re tracking 47 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT01425892Recruiting
Study of how Sjogren’s disease starts and changes over time
This study follows people with Sjogren’s disease to understand how it develops and how symptoms naturally change over time. The goal is to improve understanding and future care rather than provide a new immediate treatment.
Bethesda, MarylandAges 16–100 - NCT07772570Recruiting
Studying blood markers in coronary artery disease
This study collects blood samples and images from patients with heart muscle damage or those undergoing coronary angiography. The goal is to find new biomarkers that could improve diagnosis and treatment of coronary artery disease.
OxfordAges 18–90 - NCT02257866Recruiting
Study of blood vessel inflammation over time
This study looks at different types of blood vessel inflammation (vasculitis) to learn more about why they happen and how they progress. By joining, you may help doctors better understand these conditions and improve future treatments.
Bethesda, MarylandAges 3 years+ - NCT01202305Recruiting
Lymph node biopsies to study HIV in different patients
This study uses a small tissue sample from an often-accessible lymph node to learn how HIV affects the body. It may help researchers understand why some people control HIV better than others.
San Francisco, CaliforniaAges 18–70 - NCT01161199Recruiting
Leukapheresis study in people living with HIV
This trial uses a special blood-filtering procedure (leukapheresis) along with blood tests to better understand how HIV affects the body. It may help researchers learn more about HIV “pathogenesis,” which means what drives disease in different people.
San Francisco, CaliforniaAges 18 years+ - NCT07745036Recruiting
Progesterone receptors in preeclampsia
This study looks at how certain hormone receptors might be linked to preeclampsia, a pregnancy complication involving high blood pressure. It aims to understand why some women get preeclampsia and could help improve care in the future.
SamsunAges 18–45 - NCT06754319Recruiting
Gut bacteria and brain connection in child OCD
This study looks at how the bacteria in your gut might affect OCD in children and teens. It tests a possible link between your gut, brain, and OCD symptoms.
Shanghai, Shanghai MunicipalityAges 7–17 - NCT04634643Recruiting
Studies what causes fatty liver in teens
This study looks at why “nonalcoholic fatty liver disease” happens in teenagers and how it develops. It may help doctors better predict and prevent liver problems in children, even if there isn’t a new drug for you to take.
New Haven, ConnecticutAges 12–18 - NCT02821767Recruiting
Study of how different eye problems develop and change over time
This study follows people with eye conditions (including when the diagnosis is unclear) to learn what causes them and how they change. It may help by giving you closer eye evaluations and contributing knowledge that could improve care for future patients.
Bethesda, MarylandAges 1 month–100 years - NCT02974595Recruiting
Study of rare inflammatory conditions to learn what causes them
This study follows people with rare “autoinflammatory” conditions and sometimes their blood relatives to understand why symptoms happen and how they change over time. It may help by improving diagnosis and care for these conditions, using stored samples and genetic testing.
Bethesda, MarylandAges Up to 99 years - NCT04265599Recruiting
Study of high calcium after oil injections
This study looks at why some people develop high blood calcium after receiving an oil injection into a muscle. It may help researchers understand the cause and find better ways to treat it.
CopenhagenAges 18 years+ - NCT04720560Recruiting
Study how immune cells affect fatty liver disease
This study looks at how certain immune cells (“regulatory B cells”) may contribute to metabolic fatty liver disease. You might be able to join if you’re an adult with fatty liver but not pregnant and not on certain treatments.
AsyutAges 18–80 - NCT05026138Recruiting
Study of severe HPV disease and why it keeps coming back
This study follows people with severe or hard-to-treat HPV-related conditions (and some closely related partners/household contacts) to learn how the virus causes illness and how the immune system responds. It may help doctors better predict who will develop severe disease and guide future treatments.
Bethesda, MarylandAges 3–100 - NCT05072483Recruiting
Study of CADASIL’s natural course using blood tests and MRI
This study follows people with CADASIL (a genetic brain blood-vessel condition) to learn how it progresses over time. It uses blood and possibly tissue samples and brain MRI scans to better understand changes in the brain.
Bethesda, MarylandAges 18–100 - NCT05284006Recruiting
Non-invasive tests for Morquio A
This trial studies Morquio A (MPS IVA) using non-invasive ways to measure how the body is working, and to better understand why the condition happens. If you have Morquio A, this may help researchers learn more and improve care.
Wilmington, DelawareAges Any age - NCT05550194RecruitingPhase 4
Study of an antiviral to treat achalasia-related nerve inflammation
This trial looks at whether the antiviral medicine valacyclovir, plus Shingrix vaccine, can change disease affecting the gut’s nerve system in people with achalasia. If you’re eligible, you would complete specific swallow and pressure tests and then take the medicines for about two months.
Nashville, TennesseeAges 18–75 - NCT05636748Recruiting
Study how blood clots affect stroke, using special scans
This study looks at how blood clots form and contribute to an acute ischemic (clot-related) stroke. It uses PET-CT scanning to better understand the process and may help improve how future stroke treatments are targeted.
EdinburghAges 18 years+ - NCT05703386Recruiting
Study MRI changes in small-vessel stroke disease
This study looks at how “small-vessel” changes in the brain develop after an ischemic stroke, using repeated MRI scans. It may help researchers better understand what causes these changes and how to track them over time.
Baltimore, MarylandAges 18 years+ - NCT06093204Recruiting
Ultra-processed foods and eosinophilic esophagitis study
This study looks at how certain chemicals from ultra-processed foods (like packaged snacks and sodas) might trigger eosinophilic esophagitis, a food allergy condition. It will compare people with the disease to healthy volunteers of the same age and sex.
NaplesAges 3–65 - NCT06135870Recruiting
Study of senescent cells in uterine fibroids
This study looks at how aging cells in the uterus may cause fibroids. Researchers will collect tissue and blood samples to understand fibroid growth better.
Baltimore, MarylandAges 18–55 - NCT06203652Recruiting
Study of lymphoma causes and outlook
This study looks at why lymphoma happens and what factors affect how well people do. It collects information from patients diagnosed between 2007 and 2027 to better understand the disease.
Shanghai, Shanghai MunicipalityAges Any age - NCT06373822Recruiting
Understanding adenomyosis through genetics
This trial studies genetic factors (epigenetics and miRNAs) to understand why adenomyosis develops. By comparing tissue samples, researchers hope to find new ways to diagnose or treat this condition.
Brussels, Woluwe-Saint-LambertAges 18 years+ - NCT06513598Recruiting
Finding infection signs after abdominal cancer surgery
This study looks for ways to better predict and catch infections after major abdominal cancer surgery. If you are having surgery for certain cancers (esophagus, stomach, pancreas, liver, bile ducts, colon, or rectum), the researchers will check your blood and other samples for early signs of infection so they can start treatment sooner.
VilniusAges 18 years+ - NCT06564428Recruiting
Ovarian cancer risk prediction study with genetic testing
This study looks at whether certain genetic mutations can help predict the risk of getting ovarian cancer. It aims to better understand how these inherited changes lead to the disease, which could help with early detection and prevention.
Beijing, Beijing MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for pathogenesis?
- Yes. Clin2 currently lists 47 recruiting pathogenesis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pathogenesis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pathogenesis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.