Study of CADASIL’s natural course using blood tests and MRI
Part of Brain & nervous system, Heart & circulation clinical trials.
This study follows people with CADASIL (a genetic brain blood-vessel condition) to learn how it progresses over time. It uses blood and possibly tissue samples and brain MRI scans to better understand changes in the brain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be willing to follow the study plan for the whole study period
- Be age 18 to 100
- Have a confirmed CADASIL diagnosis or a NOTCH3 gene mutation from genetic testing
- Either be a healthy control person, or the person must have CADASIL/NOTCH3 mutation
- Be able and willing to provide blood and/or tissue samples
- Be able to do MRI scans safely (about up to 1 hour) and in a way that doctors can interpret results
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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