Clinical trials
Photodynamic Therapy (PDT) clinical trials
Below are recruiting photodynamic therapy (pdt) clinical trials, each written for real people, not researchers. We’re tracking 19 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07376824RecruitingPhase 3
Acupoint light therapy and Chinese medicine for ovarian reserve
This trial tests whether combining acupoint photodynamic therapy with traditional Chinese medicine can improve ovarian reserve in women with diminished ovarian reserve. It aims to find a gentle, non-hormonal way to support fertility.
Beijing, Beijing MunicipalityAges 25–40 - NCT06311890RecruitingPhase 2
Light therapy for moderate to severe acne
This trial tests a light-activated therapy (called photodynamic therapy) using a special gel that is put on the skin and then activated with a light to treat moderate to severe acne. It may help people who have not responded well to other treatments.
BeijingAges 18–50 - NCT06807359RecruitingPhase 1/Phase 2
Light-activated therapy for localized prostate cancer
This trial uses a special light-activated drug (photodynamic therapy) to treat prostate cancer that is still confined to the prostate. It aims to destroy the cancer while sparing healthy tissue, and may be an option for people with intermediate-risk prostate cancer who have not had other treatments.
New York, New YorkAges 18 years+ - NCT07241585Recruiting
Vitamin D and light therapy for skin cancer
This trial tests whether taking vitamin D before a special light therapy (photodynamic therapy) can help your body fight nonmelanoma skin cancers like basal or squamous cell cancer. You may join if you are scheduled for surgery to remove a skin tumor.
Cleveland, OhioAges 18 years+ - NCT05688904RecruitingPhase 1
Topical imipramine with light treatment for skin pain relief
This Phase 1 study tests whether applying imipramine cream to the skin affects pain and effectiveness when combined with a light-based skin treatment (photodynamic therapy). It’s mainly looking at safety and early signs of benefit for people with certain sun-damaged skin areas.
Fairborn, OhioAges 18 years+ - NCT03945162RecruitingPhase 2
Bladder cancer trial using light therapy in the bladder
This Phase 2 study tests a treatment called photodynamic therapy (PDT) placed directly into the bladder. It may help people whose non–muscle-invasive bladder cancer did not respond to BCG treatment or could not tolerate it.
Chicago, IllinoisAges 18 years+ - NCT07529444Recruiting
Testing ways to clean dental implants affected by infection
This study tests different methods to clean and treat dental implants that have developed an infection around them (peri-implantitis). The goal is to find the best way to remove harmful bacteria and save your implant.
ZagrebAges Any age - NCT06306638RecruitingPhase 1/Phase 2
Light therapy after radiation for inoperable airway tumors
This trial tests a new light-activated therapy (interstitial photodynamic therapy) after palliative radiation to shrink inoperable airway tumors and improve breathing. It is for people with solid cancers that block the airway from the outside and cannot be removed with surgery.
Buffalo, New YorkAges 18 years+ - NCT06307548RecruitingPhase 1/Phase 2
Image-guided surgery and light therapy for colorectal cancer
This trial tests a special dye that helps surgeons see tumors more clearly during surgery, followed by a light therapy to destroy any remaining cancer cells. It is for people with advanced or returning colorectal cancer who are already scheduled for surgery.
Buffalo, New YorkAges 18 years+ - NCT06778434RecruitingPhase 2
Using a cream to improve light therapy for veterans' sun-damaged skin
This trial tests whether adding a cream called imipramine to standard photodynamic therapy (light treatment) can reduce the immune suppression that sometimes happens after the therapy. It may help veterans with sun-damaged skin on their forearms or face.
Dayton, OhioAges 18 years+ - NCT06731881Recruiting
Light therapy to prevent infections after sinus or nose surgery
This study tests if a special light therapy can help prevent infections after sinus or nose surgeries. The treatment is given in addition to standard care and might lower the chance of needing more antibiotics.
London, LondonAges 16 years+ - NCT04400539RecruitingPhase 2
Nivolumab plus 5-ALA light treatment for pleural mesothelioma
This Phase 2 study tests whether adding nivolumab (an immunotherapy) to a one-time “light-based” treatment during a lung procedure can control malignant pleural mesothelioma that can’t be surgically removed. You may be eligible if your cancer has come back or progressed after prior platinum chemotherapy, and if your tumor is reachable for the light treatment during thoracoscopy.
LilleAges 18 years+ - NCT07009327Recruiting
Photodynamic therapy for CIN3
This trial tests a light-based treatment called photodynamic therapy for women with moderate to severe cervical changes (CIN3). It aims to destroy abnormal cells while saving healthy tissue.
BeijingAges 18–65 - NCT06982976Recruiting
Light therapy for abnormal cervical or vaginal cells
This trial tests a light-based treatment (photodynamic therapy) for high-grade or persistent low-grade abnormal cells in the cervix or vagina. It aims to destroy these cells without surgery, which may be an option for patients who want to avoid more invasive procedures.
Beijing, Beijing MunicipalityAges 18–65 - NCT07144852RecruitingPhase 3
Light therapy for skin growths on arms
This trial tests a new gel and light treatment for actinic keratosis (rough, sun-damaged spots) on the arm. It aims to see if it can safely remove these spots and prevent new ones.
Phoenix, ArizonaAges 18–85 - NCT03713203Recruiting
Light-based treatment for vulvar Paget’s disease
This study tests a special light treatment (photodynamic therapy) for non-invasive Paget’s disease on the vulva that has come back after surgery. It may help by treating remaining abnormal skin cells where surgery may not remove everything.
LilleAges 18 years+ - NCT07144345RecruitingPhase 3
Reformulated Light-Activated Cream for Actinic Keratosis on Face or Scalp
This trial tests a reformulated light-activated cream (Levulan Kerastick) for treating actinic keratosis (precancerous skin spots) on the face or bald scalp. It is a phase 3 study to see if the new version works better with fewer side effects.
Fremont, CaliforniaAges 18–85 - NCT05551299RecruitingPhase 4
Non-surgical treatment for bile duct cancer using heat or light
This trial tests whether treating hilar bile duct cancer with either radiofrequency ablation (heat) or photodynamic therapy (light-activated medicine) can help patients when surgery isn’t an option. It aims to treat the tumor directly without planned surgery soon.
AachenAges 18 years+ - NCT05918783RecruitingPhase 1
Testing a light-activated therapy in peripheral lung tumors
This Phase 1 trial tests padeliporfin, a light-activated medicine, delivered to lung tumors using robotic bronchoscopy. It may help people with small, peripheral lung cancer lesions by targeting the tumor without open surgery.
Baltimore, MarylandAges 18 years+
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Common questions
- Are there clinical trials for photodynamic therapy (pdt)?
- Yes. Clin2 currently lists 19 recruiting photodynamic therapy (pdt) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a photodynamic therapy (pdt) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a photodynamic therapy (pdt) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.