Clinical trials
Photodynamic Therapy clinical trials
Below are recruiting photodynamic therapy clinical trials, each written for real people, not researchers. We’re tracking 43 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06017817Recruiting
Light therapy for implant gum disease
This study tests a special light-activated treatment (antibacterial photodynamic therapy) to fight infection around dental implants. It may be an option for people with moderate to severe implant-related gum disease who are not smokers and do not have diabetes.
StockholmAges 18–85 - NCT06583720RecruitingPhase 1
Light therapy and probiotics for bad breath
This trial tests a new approach for treating bad breath (halitosis) using a special light therapy combined with probiotics (good bacteria). It aims to see if this combination works better than standard treatments.
São Paulo, São PauloAges 18–60 - NCT07009327Recruiting
Photodynamic therapy for CIN3
This trial tests a light-based treatment called photodynamic therapy for women with moderate to severe cervical changes (CIN3). It aims to destroy abnormal cells while saving healthy tissue.
BeijingAges 18–65 - NCT06982976Recruiting
Light therapy for abnormal cervical or vaginal cells
This trial tests a light-based treatment (photodynamic therapy) for high-grade or persistent low-grade abnormal cells in the cervix or vagina. It aims to destroy these cells without surgery, which may be an option for patients who want to avoid more invasive procedures.
Beijing, Beijing MunicipalityAges 18–65 - NCT03713203Recruiting
Light-based treatment for vulvar Paget’s disease
This study tests a special light treatment (photodynamic therapy) for non-invasive Paget’s disease on the vulva that has come back after surgery. It may help by treating remaining abnormal skin cells where surgery may not remove everything.
LilleAges 18 years+ - NCT03945162RecruitingPhase 2
Bladder cancer trial using light therapy in the bladder
This Phase 2 study tests a treatment called photodynamic therapy (PDT) placed directly into the bladder. It may help people whose non–muscle-invasive bladder cancer did not respond to BCG treatment or could not tolerate it.
Chicago, IllinoisAges 18 years+ - NCT04400539RecruitingPhase 2
Nivolumab plus 5-ALA light treatment for pleural mesothelioma
This Phase 2 study tests whether adding nivolumab (an immunotherapy) to a one-time “light-based” treatment during a lung procedure can control malignant pleural mesothelioma that can’t be surgically removed. You may be eligible if your cancer has come back or progressed after prior platinum chemotherapy, and if your tumor is reachable for the light treatment during thoracoscopy.
LilleAges 18 years+ - NCT05551299RecruitingPhase 4
Non-surgical treatment for bile duct cancer using heat or light
This trial tests whether treating hilar bile duct cancer with either radiofrequency ablation (heat) or photodynamic therapy (light-activated medicine) can help patients when surgery isn’t an option. It aims to treat the tumor directly without planned surgery soon.
AachenAges 18 years+ - NCT06576063Recruiting
Light therapy for better oral hygiene in older adults
This study tests a special light therapy (called antibacterial photodynamic therapy) used with a device called Lumoral to improve oral hygiene in older adults. It may help reduce bacteria and plaque in people who can brush their teeth and follow the study routine.
Loviisa, UusimaaAges 65 years+ - NCT06577311RecruitingPhase 2
Light therapy for facial skin cancer (SCCis)
This study tests a light-activated treatment (photodynamic therapy) for a very early form of skin cancer on the face. It may offer an alternative to surgery.
Aventura, FloridaAges 18 years+ - NCT06623201RecruitingPhase 1
Light therapy and sonidegib for multiple BCC
This trial tests a combination of blue-light therapy (a type of photodynamic therapy) and an oral medication called sonidegib for people with multiple basal cell carcinomas (BCCs). It may be an option if you have several BCCs that are not suitable for surgery or radiation, or if you prefer not to have surgery.
Phoenix, ArizonaAges 18 years+ - NCT07070453Recruiting
Light-activated therapy for gum disease treatment
This study tests whether adding a light-activated therapy (photodynamic therapy) to standard deep-cleaning can improve gum disease treatment. It is for adults with periodontitis who have not had recent gum treatment or taken certain medications.
Almada, Monte Da CaparicaAges 18 years+ - NCT07144345RecruitingPhase 3
Reformulated Light-Activated Cream for Actinic Keratosis on Face or Scalp
This trial tests a reformulated light-activated cream (Levulan Kerastick) for treating actinic keratosis (precancerous skin spots) on the face or bald scalp. It is a phase 3 study to see if the new version works better with fewer side effects.
Fremont, CaliforniaAges 18–85 - NCT07144852RecruitingPhase 3
Light therapy for skin growths on arms
This trial tests a new gel and light treatment for actinic keratosis (rough, sun-damaged spots) on the arm. It aims to see if it can safely remove these spots and prevent new ones.
Phoenix, ArizonaAges 18–85 - NCT07398339RecruitingPhase 2
Photodynamic therapy for bile duct cancer
This trial tests a light-activated drug called cosiporfin sodium for people with advanced bile duct cancer that cannot be surgically removed. The treatment targets tumors in the bile ducts and may help shrink them.
Shanghai, Pudong New AreaAges 18 years+ - NCT07488247RecruitingPhase 3
Light-Activated Gel for Diabetic Foot Ulcers
This trial tests a gel containing a light-activated drug (chlorin E6) for diabetic foot ulcers. The gel is applied to the ulcer and then activated with a special light to help the wound heal. It may be a good option if you have a foot ulcer that hasn't healed in 6 weeks or more.
Karachi, SindhAges 18 years+ - NCT07529444Recruiting
Testing ways to clean dental implants affected by infection
This study tests different methods to clean and treat dental implants that have developed an infection around them (peri-implantitis). The goal is to find the best way to remove harmful bacteria and save your implant.
ZagrebAges Any age - NCT05919238RecruitingPhase 1
Padeliporfin treatment for non-removable pancreatic cancer
This Phase 1 study tests a new cancer treatment called padeliporfin given through a special catheter to treat pancreatic ductal adenocarcinoma that cannot be removed by surgery. It aims to see how safe the treatment is and whether it can help control the tumor in people who are not surgical candidates.
Duarte, CaliforniaAges 18 years+ - NCT05918783RecruitingPhase 1
Testing a light-activated therapy in peripheral lung tumors
This Phase 1 trial tests padeliporfin, a light-activated medicine, delivered to lung tumors using robotic bronchoscopy. It may help people with small, peripheral lung cancer lesions by targeting the tumor without open surgery.
Baltimore, MarylandAges 18 years+
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Common questions
- Are there clinical trials for photodynamic therapy?
- Yes. Clin2 currently lists 43 recruiting photodynamic therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a photodynamic therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a photodynamic therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.