Clinical trials
Physiological Effects of Drugs clinical trials
Below are recruiting physiological effects of drugs clinical trials, each written for real people, not researchers. We’re tracking 27 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06535568Recruiting
Comparing one vs two blood thinners after heart artery balloon treatment
This trial tests whether taking just one blood thinner (clopidogrel) is as safe and effective as taking two (clopidogrel plus aspirin) for older adults or people at high bleeding risk who have had a drug-coated balloon procedure to open blocked heart arteries.
Milan, MIAges Any age - NCT06752759RecruitingPhase 3
Ketamine mist for depression
This trial tests if a ketamine mist you breathe in can help treat moderate to severe depression. It is for adults who are not helped enough by other treatments.
Brooklyn, New YorkAges 18–88 - NCT04289142RecruitingPhase 4
Testing memory effects of dexmedetomidine during heart surgery
This study looks at how a sleep medicine called dexmedetomidine affects thinking and memory after heart surgery. It compares cognitive outcomes over time to see if this sedation choice changes long-term brain function.
Vancouver, British ColumbiaAges 60 years+ - NCT06462196Recruiting
Study of Depression, Bipolar Disorder & Suicide Risk
This study looks at how depression, bipolar disorder, and suicide risk naturally change over time. It aims to better understand these conditions so doctors can improve treatments.
Bethesda, MarylandAges 18–120 - NCT06511908RecruitingPhase 2
Testing a new ketamine-like drug for hard-to-treat depression
This study tests a new experimental drug (2R,6R)-HNK, a chemical related to ketamine, given by IV infusion to see if it can help people with depression that hasn't improved with other treatments. The goal is to find a new option for people who have not found relief from standard antidepressants.
Bethesda, MarylandAges 18–70 - NCT07167550RecruitingPhase 3
Testing Dimephosphon for recent ischemic stroke recovery
This study tests an investigational drug called Dimephosphon to see if it helps people recover from a recent ischemic stroke (a stroke caused by a clot). It is for adults ages 35–80 whose symptoms began 24 to 72 hours ago and who have not received clot-busting treatments.
Vsevolozhsk, Leningradskaya Oblast'Ages 35–80 - NCT04234724Recruiting
Study of how ANGPTL3 gene variants affect body functions
This study looks at how different ANGPTL3 gene versions may change normal body measurements (such as blood and metabolism). It may help researchers understand why these genetic differences affect health, especially related to fats (lipids) in the body.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06725836Recruiting
Spinal cord stimulation study for spinal cord injury
This study tests how spinal cord stimulation affects brain activity in people with spinal cord injuries. It aims to understand the physiological effects using EEG (a brainwave test).
Vladivostok, Primorskiy (Maritime) KrayAges Any age - NCT06776939Recruiting
High-flow oxygen through trach tube to help weaning from a ventilator
This trial tests if high-flow oxygen delivered through a tracheostomy tube can make mucus less sticky and reduce breathing effort while you are being taken off a ventilator. It could help you breathe easier during weaning.
RotterdamAges 18 years+ - NCT03032601Enrolling by invitation
N-acetyl cysteine study for people with multiple sclerosis
This study tests whether N-acetyl cysteine (a supplement-like medicine) changes body and brain function in people with multiple sclerosis. It may help researchers understand how it affects brain chemistry and activity using special brain imaging.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04451044Enrolling by invitation
Guided heart stent planning using an inside pressure sensor
This study tests whether using a tiny pressure sensor in heart arteries during a procedure can better guide where to place a stent. It may help doctors choose the safest and most effective stent plan by more accurately measuring artery narrowing.
Birmingham, AlabamaAges 18 years+ - NCT03866382RecruitingPhase 2
Immunotherapy plus a targeted drug for rare genitourinary tumors
This Phase 2 study tests whether nivolumab and ipilimumab (immunotherapy drugs) plus cabozantinib (a targeted anti-cancer drug) can shrink or control rare cancers of the urinary/reproductive system that have spread. It may help by boosting the immune system and blocking cancer growth signals at the same time.
Birmingham, AlabamaAges 18 years+ - NCT07163182RecruitingPhase 1
Safety study of nasal CHF6467 in healthy volunteers
This study tests a new medicine called CHF6467 given as a nasal spray. It looks at how safe the medicine is, how it is absorbed and removed from the body, and what side effects it might cause. Healthy volunteers aged 18 to 55 can take part.
SofiaAges 18–55 - NCT05707806Recruiting
Brain and decision tasks to study learning
This study tests how people learn from choices and make decisions using computer tasks. Some participants also complete brain scans (MRI) to see how the brain activity matches behavior.
Baltimore, MarylandAges 18–45 - NCT07250568Recruiting
Office exercise program for low back pain in workers
This study tests if a special office exercise program can help people with low back pain feel better, reduce stress, and improve their quality of life. It includes exercises and posture advice for people who work at computers.
Depok, West JavaAges 18–58 - NCT07147231RecruitingPhase 1/Phase 2
Pidnarulex plus cemiplimab for MSS colorectal cancer
This trial tests two drugs together: pidnarulex (a targeted therapy) and cemiplimab (an immunotherapy that helps your immune system fight cancer). It is for people with advanced colorectal cancer that is microsatellite stable (MSS) and has not responded to current treatments, especially if their tumor has a MYC or FBXW7 change.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05526196Recruiting
Study how cannabis and tobacco affect reaction and feelings
This study tests how cannabis and tobacco—used together or separately—affect your thinking speed, how you feel, and body responses. You may help researchers understand these effects under controlled conditions, which could be useful for safer use and treatment decisions.
Toronto, OntarioAges 19–45 - NCT07170930Enrolling by invitation
Training program for soccer players in preseason
This trial tests a training program for soccer players during their preseason. It looks at how fitness, blood markers, and body function change. It may help soccer players improve performance and prepare for the season.
Athens, DaphniAges 18–35 - NCT06083766Recruiting
Hormone Therapy Effects on Metabolism in Transgender Adults
This study looks at how long-term gender-affirming hormone therapy affects your body's metabolism and energy use. Researchers want to understand these changes better to improve care for transgender and gender-diverse people.
Rochester, MinnesotaAges 18–40 - NCT07379606Recruiting
Exercise and cyclic sighing for stress and cognition
This study looks at how moderate exercise and a special breathing technique called cyclic sighing affect stress, thinking, and body signals in healthy young adults. It may help you learn simple ways to manage stress and improve focus.
Poznan, WielkopolskaAges 18–35 - NCT07469527Recruiting
Tonic for stress in healthy adults
This study tests if a tonic called Feel Free Classic Tonic can help lower stress in healthy adults. You will take the tonic, and the researchers will check your stress levels and how your body processes the drink.
Guelph, OntarioAges 21–55 - NCT03299179Recruiting
Female hormones and brain blood flow during MRI
This study checks how female hormones may change blood flow in the brain. You may be asked to undergo an MRI scan while hormone levels are assessed.
GhentAges 18–25 - NCT07522398Recruiting
Power Training Study for Adults Over 65
This study tests whether short, intense strength exercises can help older adults build muscle and stay stronger. You'll do exercises designed to build power (the ability to move quickly and forcefully) over several weeks, and researchers will measure changes in your strength and daily function.
Diepenbeek, FlandersAges 65–85 - NCT05545306Recruiting
Study tests how extra calories change your daily energy use
This study looks at how eating more calories affects your body’s natural heat production and total energy use over a full day. It may help researchers better understand how the body manages weight and energy.
Phoenix, ArizonaAges 18–60
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Common questions
- Are there clinical trials for physiological effects of drugs?
- Yes. Clin2 currently lists 27 recruiting physiological effects of drugs studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a physiological effects of drugs trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a physiological effects of drugs trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.