Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,929 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05838287RecruitingPhase 4
Pioglitazone for heart failure with preserved pumping in type 2 diabetes
This trial tests whether pioglitazone (a diabetes medicine) helps people who have type 2 diabetes and a specific type of heart failure where the heart pumps normally. It may improve heart failure symptoms and function in carefully selected patients.
San Antonio, TexasAges 30–70 - NCT05662111RecruitingPhase 2
Etidronate treatment for brain calcifications in Fahr disease
This Phase 2 study tests whether etidronate (a medicine that affects bone-calcium handling) can help people with Fahr disease or a similar condition marked by calcium deposits in the brain. It will also check safety and whether certain tests can track changes over time.
Utrecht, UtrechtAges 18 years+ - NCT05834777RecruitingPhase 3
Prevent low blood pressure during dialysis by blocking bradykinin
This Phase 3 trial tests a medicine that blocks a body signal (bradykinin) to help prevent dangerous drops in blood pressure during hemodialysis. If you often get “intradialytic hypotension,” this study may help you dialyze more safely.
Nashville, TennesseeAges 18–80 - NCT05829317RecruitingPhase 4
Magnesium to prevent new atrial fibrillation in ICU patients
This trial tests whether giving magnesium can lower the chance of developing new irregular heartbeat (atrial fibrillation) in critically ill adults in the ICU. If you are at risk but do not already have this rhythm issue, magnesium may help prevent it.
Hamilton, OntarioAges 18 years+ - NCT05703672RecruitingPhase 3
Switching smokers to e-cigarettes who do not want to quit
This study tests whether switching from regular cigarettes to e-cigarettes helps smokers who are not interested in quitting. You would also be offered varenicline and regular check-ins to compare outcomes over time.
Kansas City, MissouriAges 21 years+ - NCT05897320RecruitingPhase 3
Eptinezumab trial for kids with episodic migraine
This Phase 3 study tests eptinezumab to reduce migraine attacks in children who have episodic migraine (not daily chronic migraine). It may help by lowering the number of headache days and migraine days over time. You must complete a headache diary during screening to be considered.
Stamford, ConnecticutAges 6–17 - NCT05635877RecruitingPhase 4
Low-dose heart-rate medicine after surgery in frail older adults
This trial tests whether a low dose of esmolol (a short-acting heart-rate medicine) can reduce heart muscle injury after non-heart surgery in older, frail people. It may help lower the chance of heart-related complications around the time of surgery.
Jinan, ShandongAges 65–90 - NCT05272254RecruitingPhase 2
Povidone iodine in kids’ dental cavities surgery
This trial tests whether povidone iodine helps prevent problems or improves outcomes when children with severe early childhood cavities need dental treatment in the operating room. You may be able to join if your child fits the age and dental needs and has no iodine-related or thyroid problems.
Rochester, New YorkAges 2 years–5.9 years - NCT05473793Recruiting
Dried vegetables study for constipation and gut bacteria
This study tests whether eating a dried vegetable can improve bowel habits and change gut bacteria. It may help people who feel their bowel function is not working well and have hard or infrequent stools.
Wageningen, GelderlandAges 20–80 - NCT05616819Recruiting
Morning light program to improve mood in some service members
This study tests whether getting morning light exposure can improve mood for service members who currently have mild or more depression symptoms. You’d follow a plan for morning light over about 6 weeks, and the researchers check changes in mood.
Tucson, ArizonaAges 18–60 - NCT05398367Recruiting
Supplement study to help low milk supply during breastfeeding
This study tests whether a supplement (either an active “galactagogue” or a placebo) can increase milk supply in people who feel they have low breast milk. You would have several check-ins and milk/milk-expression measurements to see if your milk volume changes.
Rock Hill, South CarolinaAges 18–40 - NCT05318534RecruitingPhase 1
Testing a new medicine for Cold Agglutinin Disease
This Phase 1 study checks whether an investigational medicine is safe and tolerable, and how the body processes it. For people with Cold Agglutinin Disease, it also looks at early blood markers of whether the disease responds.
LeedsAges 18 years+ - NCT07237880Recruiting
Papaverine to shorten pushing phase of labor
This study tests whether a medicine called papaverine can shorten the pushing phase of labor in women whose labor is started with a balloon catheter. If you are planning a vaginal delivery and meet the other criteria, you may be able to join.
HaderaAges 18–50 - NCT05203965RecruitingEarly Phase 1
Brain imaging study testing mavoglurant in alcohol risk
This early-stage study uses brain scans to understand how brain signaling tied to alcohol vulnerability works, and it tests mavoglurant, a medicine that blocks a brain receptor. Results may help researchers learn why some people are more vulnerable to alcohol problems.
Hartford, ConnecticutAges 18–45 - NCT05071131Recruiting
Inulin supplement to improve gut health in kidney disease
This trial studies whether taking inulin—a dietary fiber—can improve gut bacteria and the gut barrier in people with end-stage kidney disease on hemodialysis. It may help reduce gut-related problems that can affect overall health in kidney disease.
BerlinAges 18–75 - NCT05076019Recruiting
Atorvastatin during heart valve surgery for patients over 60
This trial studies whether taking atorvastatin (a cholesterol medicine) around the time of surgical aortic valve replacement can improve outcomes. It is mainly for people who have not taken similar medicines recently and do not have certain heart rhythm or liver/kidney problems.
OdenseAges 60–95 - NCT05245591RecruitingPhase 2/Phase 3
Pentosan for bladder irritation after pelvic radiation
This trial studies whether pentosan polysulfate sodium can reduce bladder bleeding (hematuria) and urinary symptoms caused by radiation cystitis after pelvic cancer radiation. It may help people who are still having these bladder problems more than 6 months after radiation.
TaipeiAges 20 years+ - NCT05080569RecruitingPhase 4
Extra support after IUI for couples with unclear infertility
This study tests whether adding support in the period after ovulation (the “luteal phase”) helps people who are starting IUI (intrauterine insemination) because their infertility is unexplained. It’s designed to see if the added care improves chances when mild ovarian stimulation is used.
UtrechtAges 18 years+ - NCT05224960RecruitingPhase 2
Stem cell treatment for worsening liver cirrhosis
This trial tests umbilical-cord stem cells to see if they can improve outcomes in people with decompensated (worsening) cirrhosis. You may be considered if your liver disease is moderate to severe (MELD 15–30) and you do not have certain high-risk problems right now.
Lanzhou, GansuAges 18–75 - NCT05139719RecruitingPhase 2
HEC585 trial for slowing lung scarring decline
This Phase 2 study tests whether HEC585 can slow the decline in lung function in people with progressive fibrosing interstitial lung disease (PF-ILD). It may help preserve breathing capacity and breathing tolerance over time.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05252754RecruitingPhase 3
Medicines to prevent pancreas swelling after ERCP
This Phase 3 study tests whether putting an anti-inflammatory medicine into the rectum (indomethacin) plus taking an immune-suppressing pill (tacrolimus) works better than using the two medicines in a different combination to prevent pancreatitis after an ERCP procedure. If you qualify, you may be assigned to one of the treatment options to lower your risk of post-ERCP pancreas inflammation.
Baltimore, MarylandAges 18 years+ - NCT04770012RecruitingPhase 3
Aspirin or clopidogrel after heart transplant
This study tests antiplatelet medicines (like aspirin or clopidogrel) in people who have had a heart transplant. The goal is to see if these medicines can safely help prevent blood-related complications after transplant.
Vancouver, British ColumbiaAges 18 years+ - NCT05136976RecruitingPhase 3
Rituximab for anti-MAG neuropathy in specific patients
This Phase 3 study tests rituximab, an antibody medicine, for people with a particular type of nerve damage called anti-MAG–related demyelinating polyneuropathy. It aims to see if rituximab improves symptoms or function in patients who are considered “good responders.”
BrestAges 18 years+ - NCT05229224Recruiting
Study of a new device for frequent tension headaches
This pilot study tests a device approach (“Osteo-Fluidic-Sensitive”) for people who get frequent episodic tension-type headaches. It aims to see whether the device is safe and can reduce headache burden for the right kind of headache pattern.
PoitiersAges 18–75
Hear when a new Placebo - Control trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,929 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.