Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,962 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05761860RecruitingEarly Phase 1
Oxytocin to lower opioid misuse risk and pain in older adults
This early-phase study tests whether oxytocin (a hormone-like medication) can reduce how “appealing” opioids feel and also reduce pain. It’s aimed at older adults who have used opioids before but are not currently dealing with chronic pain most days.
Gainesville, FloridaAges 45–85 - NCT05762952RecruitingPhase 1
Dapagliflozin study for heart micro-blood-flow symptoms in women
This early-phase study tests whether dapagliflozin can improve tiny blood-vessel function in women who have heart-ache-like symptoms but no major blockage on heart scans. If it works, it may help symptoms related to “microvascular” heart circulation problems.
Charlottesville, VirginiaAges 18–99 - NCT05764057RecruitingPhase 3
Dapagliflozin to help the heart heal after a heart attack
This trial tests whether dapagliflozin (a diabetes medicine also used for heart protection) can reduce harmful heart “remodeling” after an acute heart attack. It may help your heart function and structure recover over the following 6 months.
ParisAges 18 years+ - NCT05764733RecruitingPhase 4
How bone exercise, alendronate, and diet affect bone strength
This trial studies whether doing a structured bone-focused exercise program, taking alendronate (a medication that slows bone loss), and making a calorie-reducing diet can improve bone strength in people with low bone density. It also compares different combinations to see what helps most and is safest for you.
Aurora, ColoradoAges 60 years+ - NCT05767450Recruiting
Test for early type 1 diabetes in children
This study looks at children who have just started insulin for new-onset type 1 diabetes. It aims to test an intervention early in the course of the disease, which may help change how the immune system and diabetes progress.
Milan, MilanAges 7–17 - NCT05772013RecruitingPhase 4
Checking azithromycin prevention for COPD flare-ups
This Phase 4 study looks at optimizing how people with COPD take azithromycin to reduce flare-ups (exacerbations). If you already take azithromycin regularly, the trial may test ways to improve how it’s used safely.
CambridgeAges 40 years+ - NCT05772104RecruitingPhase 3
Test a Chinese herbal capsule for generalized anxiety
This Phase 3 trial studies Shugan Jieyu Capsule to treat generalized anxiety disorder (GAD). It aims to see if it can reduce anxiety symptoms in people who fit specific anxiety severity and traditional diagnosis criteria.
BeijingAges 18–65 - NCT05772871RecruitingPhase 4
Prednisone plus herbal granules for children with nephrotic syndrome
This trial tests whether adding Huaiqihuang granules to prednisone can improve outcomes for children with primary, hormone-sensitive nephrotic syndrome. It also closely monitors safety to see if the combination causes fewer or more side effects than usual care.
Hefei, AnhuiAges 1.5 years–18 years - NCT05773586RecruitingPhase 1
Study of a new medicine for anemia, first tested for safety
This Phase 1 trial tests how safe APG-5918 is, how the body processes it, and looks for early signs it may help people with certain types of anemia. It may include healthy volunteers and people with anemia, but the study is very selective to protect participants.
Guangzhou, GuangdongAges 18 years+ - NCT05776069RecruitingPhase 1/Phase 2
Test drug VGA039 for bleeding control in von Willebrand disease
This Phase 1/2 study tests VGA039 in healthy adults and people with von Willebrand disease (VWD). The goal is to see if the drug is safe and how it affects bleeding-related factors, especially in people who have symptoms.
Los Angeles, CaliforniaAges 12–60 - NCT05778188RecruitingPhase 2
RLS-0071 for newborns with moderate or severe HIE
This trial studies whether RLS-0071 is safe and can help some newborns with moderate or severe hypoxic-ischemic encephalopathy (HIE), a brain injury caused by low oxygen around birth. Babies in the study also receive standard whole-body cooling (therapeutic hypothermia), and the researchers will watch for side effects and early signs of benefit.
Little Rock, ArkansasAges Up to 10 hours - NCT05778591RecruitingPhase 2
Low-dose buprenorphine to improve social drive in schizophrenia
This study tests whether low-dose buprenorphine can improve social motivation in people with schizophrenia. It compares social motivation changes while keeping participants stable on treatment and avoiding certain medicines and substances.
Los Angeles, CaliforniaAges 18–60 - NCT05778617RecruitingPhase 3
Ambroxol to Slow Parkinson’s Disease Progression
This trial studies whether ambroxol (or a placebo) can slow the progression of Parkinson’s disease. It may help by aiming to change how the disease develops over time.
BirminghamAges 35–75 - NCT05782244RecruitingPhase 2
Sildenafil trial for long-term brain blood-flow problems after TBI
This Phase 2 study tests whether sildenafil (a medication better known for erectile function) can improve long-term symptoms and brain blood-flow issues after a past traumatic brain injury (TBI). It may help by improving blood vessel function in the brain and possibly reducing persistent post-concussion symptoms.
Philadelphia, PennsylvaniaAges 18–70 - NCT05785065RecruitingPhase 2
Mycophenolate for early lung scarring in systemic sclerosis
This Phase 2 study tests whether mycophenolate mofetil (MMF) can slow or improve early, mild lung scarring in people with systemic sclerosis. It’s meant for systemic sclerosis patients who have lung involvement on a CT scan but still have good breathing test results.
Montreal, QuebecAges 18 years+ - NCT05788276RecruitingPhase 4
Dapagliflozin to help transplanted kidneys stay healthy
This study tests whether dapagliflozin can preserve the structure and function of a kidney transplant. You may be asked to take dapagliflozin on top of usual transplant medicines to see if it helps the new kidney work better over time.
Oslo, OsloAges 18–75 - NCT05790356Recruiting
Fecal transplant to treat rheumatoid arthritis symptoms
This study tests whether transferring stool from a screened healthy donor into the gut can improve rheumatoid arthritis (RA) in people whose RA is in remission or low activity. It’s mainly trying to change the gut bacteria to reduce RA symptoms or flare-ups.
London, OntarioAges 18 years+ - NCT05791396RecruitingPhase 1/Phase 2
Fecal microbiome therapy to clear hard-to-treat gut germs
This trial looks at a treatment made from stool donors (called fecal microbiome therapy) to help remove carbapenem-resistant gut bacteria in the body. It’s mainly for adults who recently tested positive for these bacteria on a rectal swab, and it checks whether the therapy can help eradicate the germs.
RomaAges 18–85 - NCT05795478Recruiting
Oxycodone plus pregabalin for long-term pain after spinal surgery
This trial studies whether taking oxycodone together with pregabalin (both pain medicines) can reduce chronic pain that can linger after spinal surgery. If you qualify, you may be asked to rate your pain and complete questionnaires during recovery.
BeijingAges 18 years+ - NCT05797831RecruitingPhase 2/Phase 3
Maintenance treatment for TP53-wildtype endometrial cancer
This trial tests navtemadlin as a maintenance (ongoing) treatment to help prevent endometrial cancer from coming back after chemotherapy works. It is mainly for people whose cancer has certain genetic features (TP53 “wildtype”) and who had a strong response to first-line taxane–platinum chemo.
Vallejo, CaliforniaAges 18 years+ - NCT05802264RecruitingPhase 1
Inhaled amphotericin B for healthy volunteers and cystic fibrosis
This early-phase study tests how different doses of an inhaled medicine (amphotericin B) work and are tolerated. It includes healthy adults and people with cystic fibrosis (CF) to see if the dose schedule is safe and potentially beneficial.
Canberra, Australian Capital TerritoryAges 16 years+ - NCT05805683Recruiting
Calcitonin for nerve pain after spinal cord injury
This study tests whether calcitonin can prevent or lessen nerve pain after a spinal cord injury. It may help reduce how often neuropathic (nerve-type) pain happens and how severe it becomes.
Tanta, Gharbia GovernorateAges 18 years+ - NCT05806346Recruiting
TXA dosing for heart surgery patients on bypass
This trial studies whether giving tranexamic acid (TXA) based on patient needs during heart surgery works better than a one-size-fits-all approach. It may help reduce bleeding during surgery, while monitoring for clotting-related side effects.
SeoulAges 19 years+ - NCT05816798RecruitingPhase 2/Phase 3
Laser treatment to reduce chronic knee pain before weight-surgery
This trial tests whether photobiomodulation (a type of laser/light therapy) can reduce chronic pain in both knees for people preparing for bariatric (weight-loss) surgery. If you have knee pain that limits daily life, the treatment may help you feel better while you’re in the pre-surgery rehabilitation period.
Goiânia, GoiásAges 18–70
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,962 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.