Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,962 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05701969RecruitingEarly Phase 1
Melatonin for sleep during night shifts in residents
This early study tests whether melatonin can improve sleep patterns for doctors-in-training during overnight “night float” shifts. It may help you feel more rested and adjust to night work.
Charlottesville, VirginiaAges 18 years+ - NCT05702398RecruitingEarly Phase 1
Vitamin A and niacinamide for high-risk skin cancer
This early trial tests whether adding vitamin A and niacinamide (a form of vitamin B3) can help people with a history of certain skin cancers reduce new disease. It is designed for adults with specific prior skin cancer or skin lesion treatment patterns.
Providence, Rhode IslandAges 18 years+ - NCT05708859RecruitingPhase 4
Tirzepatide to slow plaque buildup in coronary arteries
This trial studies tirzepatide to see if it can slow the progression of coronary artery plaque in people with type 2 diabetes. It uses special heart CT scans to track changes over time.
Torrance, CaliforniaAges 40–80 - NCT05709249RecruitingPhase 3
Chinese herbal medicine to help prevent colon cancer return
This Phase 3 study tests whether a Chinese herbal “decoction” (called XLJDOD) given after surgery and chemo can lower the chance that colon cancer comes back. It may help people with higher-risk colon cancer (Stage IIIB or IIIC) stay cancer-free longer.
NanjingAges 20–80 - NCT05713877RecruitingPhase 2
Melatonin to treat confusion in ICU patients
This Phase 2 trial tests whether melatonin can reduce delirium, a sudden confusion that can happen in the ICU. If you qualify, you may be given melatonin to see if it improves alertness and comfort during an expected longer ICU stay.
Montreal, QuebecAges 18 years+ - NCT05716100RecruitingPhase 3
Study drug for focal epilepsy that isn’t controlled on current meds
This trial tests XEN1101 compared with a placebo (inactive pill) in people with focal-onset seizures that haven’t been fully controlled despite trying at least two anti-seizure medicines. If you qualify, you may help researchers see whether the study drug reduces seizure frequency and improves control.
Little Rock, ArkansasAges 18 years+ - NCT05719467RecruitingPhase 3
Safety check of medicine to start labor
This Phase 3 study tests the safety of a medicine used to help start labor (“induction”). It may help by aiming for a safer, smoother induction process for people who are ready to deliver and meet specific pregnancy and health criteria.
LørenskogAges 18–50 - NCT05723198RecruitingPhase 3
Baricitinib for severe childhood hair loss from alopecia areata
This trial tests whether baricitinib can improve severe alopecia areata (patchy, autoimmune hair loss) in children and teens. It’s meant for people who have had long-lasting, severe hair loss and have tried other treatments without enough benefit.
Birmingham, AlabamaAges 6–17 - NCT05722782RecruitingPhase 2
Kidney stone pain treatment after ER discharge
This study compares an anti-inflammatory pain medicine (NSAID) given by mouth versus acetaminophen (paracetamol) or placebo after you leave the emergency room for a “renal colic” (kidney stone pain). It looks at whether the NSAID helps control pain better and whether it’s safe for people with uncomplicated kidney stone pain.
MonastirAges 18 years+ - NCT05725512RecruitingPhase 4
Prednisolone to prevent unexplained recurrent miscarriages
This trial tests whether a medicine called prednisolone can help prevent further miscarriages in people who have had recurrent miscarriages with no known cause. If you qualify, you would take prednisolone early in pregnancy and the study team would watch whether more losses occur.
Leiden, South HollandAges 18–40 - NCT05730023Recruiting
Testing a new approach for primary progressive aphasia diagnosis
This study focuses on people with primary progressive aphasia (PPA), a condition that affects language over time. It tests a “multimodal” set of assessments and treatment planning, which may help your care team diagnose and support you more accurately.
Brescia, BSAges 40 years+ - NCT05732051RecruitingPhase 2
Nicotinamide riboside to protect the heart during breast cancer chemo
This trial tests whether nicotinamide riboside can help prevent heart problems caused by a common breast-cancer chemotherapy (anthracyclines). If you’re eligible, you’ll be followed to see how your heart is doing during treatment.
Lørenskog, AkershusAges 18 years+ - NCT05737342Recruiting
Test supplement to lower A1c and steady blood sugar
This trial studies ANKASCIN 568-P products to see if they can lower A1c (a blood sugar average) and help regulate blood glucose. It may help people with early blood sugar problems, but you must avoid diabetes medicines during the study.
TaipeiAges 20 years+ - NCT05737355Recruiting
Test food product for cholesterol balance and lipid levels
This trial tests whether ANKASCIN 568-P products can improve blood cholesterol levels (like LDL and HDL) in people with mild “lipid” (cholesterol/fat) imbalance. It may help by lowering “bad” cholesterol and improving balance, especially if you’re not taking cholesterol-lowering medicine right now.
TaipeiAges 20 years+ - NCT05739864RecruitingPhase 1/Phase 2
Test of donor gut bacteria for ulcerative colitis
This early-stage study tests whether a one-time transfer of “donor gut bacteria” can improve ulcerative colitis. It’s designed for people with mild to moderate ulcerative colitis who are stable on maintenance treatment.
Rome, LazioAges 18–75 - NCT05740722RecruitingPhase 2
Nicotinamide riboside for progressive multiple sclerosis
This Phase 2 trial studies whether a vitamin-like supplement called nicotinamide riboside can slow or improve disability in progressive multiple sclerosis. It may help people whose symptoms have been steadily getting worse over the last 2 years.
BergenAges 18–65 - NCT05744219RecruitingPhase 3
Iron after major abdominal surgery to improve recovery
This Phase 3 study tests whether giving iron (as ferric carboxymaltose) after complex major surgery can improve recovery by helping your body rebuild blood and oxygen levels after blood loss. It may help patients who are having certain types of aortic, liver, or pancreas operations.
Uppsala, SverigeAges 18 years+ - NCT05744479RecruitingPhase 4
Metformin to reduce weight gain from antipsychotic medicines
This trial tests whether metformin can help adults with intellectual disability who gained weight from long-term antipsychotic medicines. If you qualify, you may be assigned metformin to improve weight and related health measures.
Toronto, OntarioAges 16–65 - NCT05744687RecruitingPhase 2/Phase 3
Letrozole plus SPH4336 versus letrozole alone for breast cancer
This study tests whether adding SPH4336 to letrozole works better than letrozole plus a placebo for treating hormone-receptor–positive, HER2-negative breast cancer in people starting first-line treatment. It may help slow cancer growth more effectively if the added drug is beneficial.
Fuzhou, FujianAges 18–75 - NCT05746143RecruitingPhase 4
Zolpidem during recovery after lower-back fusion surgery
This trial studies whether taking zolpidem around the time of recovery from lower-back (lumbar) fusion surgery affects outcomes. It may help doctors understand how sleep medicine can (or can’t) support recovery in certain people.
Los Angeles, CaliforniaAges 18–75 - NCT05753059RecruitingPhase 1
Study why some water pills stop working in heart failure
This Phase 1 study looks at why “water pills” (diuretics) like bumetanide may not remove fluid as expected in people with heart failure. The results may help clinicians improve treatment strategies for fluid control in the future.
New Haven, ConnecticutAges 18 years+ - NCT05754073RecruitingPhase 2
Oxytocin to improve bone health in children with autism
This Phase 2 study tests whether oxytocin can help improve bone health in children and teens with autism spectrum disorder. It also checks safety by monitoring symptoms and doing blood tests and imaging.
Boston, MassachusettsAges 6–18 - NCT05755737RecruitingPhase 2
Ondansetron to prevent fainting episodes from vasovagal syncope
This Phase 2 study tests whether ondansetron can help prevent future fainting (vasovagal syncope) in adults who have had recent episodes. If it works, it may reduce how often you faint and improve safety in everyday situations.
Calgary, AlbertaAges 18–100 - NCT05759468RecruitingPhase 2
Add NAD to help protect kidneys in diabetes
This Phase 2 study tests whether adding NAD can improve kidney health in people with diabetes-related kidney disease. It is designed for people with certain urine lab results showing kidney stress, while keeping blood sugar and safety limits within range.
Boston, MassachusettsAges 30 years+
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,962 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.