Clinical trials
PTSD clinical trials
Below are recruiting ptsd clinical trials, each written for real people, not researchers. We’re tracking 296 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06335407RecruitingPhase 1
Testing a new under-the-tongue med for alcohol use and trauma
This study tests a new sublingual (under-the-tongue) medication for people with alcohol use disorder who have also had a traumatic life event. It aims to see if the medication can help reduce drinking and related symptoms.
West Haven, ConnecticutAges 21–65 - NCT06330779Recruiting
Trauma-adapted yoga for teens with PTSD or ADHD
This trial tests if a special yoga program helps teenagers with PTSD or ADHD feel better. It is designed to be safe and supportive for their mental health.
GothenburgAges 12–18 - NCT06335043Recruiting
Personalized medication matching for veterans with OSI
This trial tests whether using genetic information to guide medication choices can improve treatment for veterans with operational stress injuries (OSI). It aims to help find the right medication faster and with fewer side effects.
London, OntarioAges 18 years+ - NCT06037785Recruiting
Self-management support after an ICD shock
This study tests a self-management program to help people who have received a shock from their implantable cardioverter-defibrillator (ICD). The goal is to see if this program can improve recovery and well-being after a shock.
Seattle, WashingtonAges 18 years+ - NCT06296186Recruiting
PTSD treatment for veterans in substance use recovery
This trial tests a condensed form of prolonged exposure therapy for PTSD in veterans who are also receiving treatment for a substance use disorder. The goal is to help you process trauma and reduce substance use together.
San Diego, CaliforniaAges 18 years+ - NCT06294106Recruiting
Brain stimulation for PTSD in veterans and first responders
This study tests a new type of brain stimulation (eTMS) to help reduce PTSD symptoms in veterans and first responders. It uses an MRI to guide the treatment, and aims to see if it can improve your quality of life.
Roanoke, VirginiaAges 18–65 - NCT06288711Recruiting
Video therapy for PTSD in people taking opioid medication
This trial tests a therapy called prolonged exposure (a type of talk therapy) delivered via video calls to help people with both opioid use disorder and PTSD. It aims to see if this approach can reduce PTSD symptoms.
Burlington, VermontAges 18 years+ - NCT06290778Enrolling by invitation
Mental health prevention training for fire fighter trainees
This study tests a program where peers teach emotion regulation skills to help prevent mental health issues in new fire fighters. You would be asked to complete surveys and attend training sessions.
Waco, TexasAges 21 years+ - NCT06278922Recruiting
A therapy toolkit for Deaf people with alcohol and trauma issues
This study tests a therapy toolkit designed for Deaf or hard-of-hearing people who struggle with alcohol use and have experienced trauma. The therapy is provided in ASL via video sessions, and the goal is to see if it helps reduce drinking and PTSD symptoms.
Worcester, MassachusettsAges 18 years+ - NCT06261463Recruiting
Peer-led support group for refugee families in Chicago
This study is testing a support program led by trained peers to help refugee families strengthen family bonds and cope with challenges. It is designed for Arabic-speaking families who have recently settled in Chicago.
Chicago, IllinoisAges 12–55 - NCT06262178Recruiting
Parenting support for mothers in military families
This study tests a parenting program designed to help mothers in military families cope with past trauma and improve their relationship with their child. The program aims to reduce PTSD and depression symptoms while increasing parenting confidence.
El Paso, TexasAges 18 years+ - NCT06218381Recruiting
Brief exposure for PTSD in combat veterans
This study tests a very brief exposure therapy to help U.S. combat veterans with PTSD. It is designed for veterans who have not had recent mental health treatment and experienced combat trauma within the last 10 years.
Los Angeles, CaliforniaAges 18–50 - NCT06219408Recruiting
Stepped care for chronic pain and PTSD
This study tests a stepped-care program that combines complementary health approaches for people who have both chronic pain and PTSD. It aims to help patients manage both conditions together using treatments like acupuncture, massage, or mind-body therapy.
Seattle, WashingtonAges 18 years+ - NCT06210711Recruiting
Prolonged exposure therapy for trauma injury patients
This study tests if prolonged exposure therapy can help people who were injured in a trauma and admitted to a Level I trauma center. It aims to reduce the psychological impact of the traumatic event, such as PTSD symptoms.
Dallas, TexasAges 18–75 - NCT06162741Recruiting
Brief mindfulness training for Veterans in primary care
This study tests whether brief mindfulness training offered in VA primary care can help Veterans with symptoms of PTSD, depression, or anxiety. It aims to see if this approach works well in everyday clinic settings.
Phoenix, ArizonaAges 18 years+ - NCT06127342Recruiting
Exercise and emotional learning for PTSD
This study tests whether exercise can help people with PTSD learn to feel safer in their bodies. You will do some exercise sessions and emotional learning tasks, and have an MRI brain scan to see how your brain changes.
Lexington, KentuckyAges 18–64 - NCT06088303Recruiting
Improving PTSD treatment through better communication
This study tests if improving how you talk with your doctor can make PTSD treatment work better. You can join if you have PTSD and have been on stable medications for at least 4 weeks.
Boston, MassachusettsAges 18 years+ - NCT03755401Recruiting
Therapy trial for PTSD after prior treatment didn’t fully help
This trial studies a specific talk-therapy approach (psychodynamic psychotherapy) for people with post-traumatic stress disorder (PTSD) who still have significant symptoms despite prior treatment. You may be able to join if your PTSD symptoms are in a moderate range and you can safely participate without urgent safety risks or certain other conditions.
New York, New YorkAges 18–70 - NCT06044675RecruitingPhase 2
MDMA plus therapy for PTSD – a study with a partner
This study tests whether MDMA, combined with a type of talk therapy called CBCT (cognitive behavioral conjoint therapy), is more effective than CBCT alone for treating PTSD. You and a close partner will both participate in therapy sessions and take MDMA together.
Toronto, OntarioAges 18–80 - NCT06035809Recruiting
Smart treatment study for PTSD using brain activity feedback
This study tests a new therapy called SMART, which uses brain imaging to help regulate arousal linked to PTSD. It aims to see if combining brain feedback with therapy reduces PTSD symptoms.
London, OntarioAges 18–65 - NCT06002633Recruiting
Alcohol effects and brain responses in PTSD
This study explores how people with PTSD respond to alcohol and how their brains handle approach or avoidance situations. You may participate if you drink alcohol occasionally and are between 21 and 60 years old.
Austin, TexasAges 21–60 - NCT06000475Recruiting
Memory boosting therapy for PTSD in veterans
This trial is testing a type of therapy called Cognitive Processing Therapy (CPT) for PTSD, along with memory exercises to help enhance the therapy's effects. It is for veterans who have PTSD and want to see if adding memory training can improve their treatment.
Philadelphia, PennsylvaniaAges 60 years+ - NCT05995678Recruiting
STEP Home Workshop for veterans adjusting to civilian life
This pilot study tests a workshop called STEP Home to help veterans who recently left the military and are having trouble readjusting. The goal is to improve their transition and reduce suicide risk.
Boston, MassachusettsAges 18–65 - NCT05974176Recruiting
Study on stress, trauma symptoms, and family support
This study looks at how racial and cultural stress may affect trauma-related emotional reactions in children and their parents/guardians. It may help researchers understand what kinds of support work best for families dealing with trauma.
New York, New YorkAges 5–17
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Common questions
- Are there clinical trials for ptsd?
- Yes. Clin2 currently lists 296 recruiting ptsd studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ptsd trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ptsd trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.