Clinical trials
PTSD clinical trials
Below are recruiting ptsd clinical trials, each written for real people, not researchers. We’re tracking 296 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05989841RecruitingPhase 1/Phase 2
Helping women after sexual assault who use cannabis
This study tests a new approach to help women who have recently experienced a sexual assault and use cannabis. It explores whether reducing anxiety about physical symptoms can help prevent long-term PTSD and cannabis problems.
Minneapolis, MinnesotaAges 18 years+ - NCT05959434RecruitingPhase 2
Therapy program to reduce drinking relapse and PTSD symptoms
This Phase 2 study tests a combined therapy approach for people who have both alcohol use disorder and post-traumatic stress disorder (PTSD). It aims to help you process stressful memories and lower the chances of relapse back to heavy drinking.
Charleston, South CarolinaAges 18 years+ - NCT05843695Recruiting
Therapy study for PTSD and anxiety in veterans
This trial tests a psychotherapy approach to help veterans and service members who have PTSD and/or anxiety disorders. You may be randomly assigned to different therapy conditions, and the study aims to improve quality of life and reduce anxiety and PTSD symptoms.
Houston, TexasAges 18 years+ - NCT05821634Enrolling by invitation
Personalized telehealth counseling for anxiety and alcohol use
This study personalizes how telehealth counseling is delivered for people dealing with anxiety or trauma-related symptoms and alcohol use problems. It may help by tailoring counseling timing and approach to what you need.
Piscataway, New JerseyAges 18–65 - NCT05812131Recruiting
Online training for behavioral health providers
This study tests an online training program for providers to help patients cope. If you are a behavioral health provider, you may learn new skills to support your patients.
Charleston, South CarolinaAges 18 years+ - NCT05751473Recruiting
Reducing PTSD symptoms for first responders and frontline health workers
This study tests a way to help reduce PTSD symptoms in first responders and frontline healthcare workers. You may join a main treatment study, and some participants may also take part in follow-up questions to learn what helped.
San Diego, CaliforniaAges 18 years+ - NCT05723588RecruitingPhase 2
TMS brain stimulation to help veterans quit smoking with PTSD
This Phase 2 study tests whether targeted brain stimulation (TMS) can improve smoking quit outcomes in Veterans who also have PTSD. It also uses brain imaging (MRI) to understand what changes in the brain may help people quit.
Durham, North CarolinaAges 18–75 - NCT05534243Recruiting
A breathing and brain-signal study for adults on ventilators
This study looks at brain activity during care for adults who are on a breathing machine through a tube in the windpipe. It may help doctors understand how to monitor recovery and guide care after intubation.
Iowa City, IowaAges 18 years+ - NCT05486793Recruiting
Study of treatment for PTSD symptoms during pregnancy
This study looks at a treatment approach for post-traumatic stress disorder (PTSD) or PTSD-like symptoms in pregnant people. It may help reduce PTSD symptoms during pregnancy, as long as you meet the symptom and care-planning requirements.
Boston, MassachusettsAges 18–50 - NCT05441280RecruitingPhase 2
Pimavanserin to improve sleep in veterans with PTSD
This Phase 2 trial studies pimavanserin, a medicine meant to improve insomnia, in veterans who also have PTSD. It may help reduce problems with falling asleep, staying asleep, or waking too early that affect daytime functioning.
Houston, TexasAges 18–64 - NCT05414708Recruiting
Art therapy for veterans with PTSD symptoms
This study tests whether art therapy can improve emotional well-being in military members who have significant PTSD symptoms. You would answer questionnaires and likely take part in art-making sessions as part of the treatment being studied.
Bethesda, MarylandAges 18–64 - NCT05427500Enrolling by invitationPhase 3
Nerve block treatment for PTSD with strong stress-and-alertness symptoms
This Phase 3 study tests whether a procedure called a stellate ganglion block can reduce PTSD symptoms, especially feeling highly “on edge” (hyperarousal). You may join if you have PTSD despite appropriate usual treatments and are able to go through the procedure safely.
Ottawa, OntarioAges 18–69 - NCT05380050Recruiting
Comparing online and in-person memory training for veterans with mild brain injury and PTSD
This study compares two ways of delivering a memory and thinking skills program to veterans with both mild traumatic brain injury (mTBI) and post-traumatic stress disorder (PTSD). The goal is to see if doing the training online is as effective as doing it in person, which could make it easier for more veterans to get help.
Gainesville, FloridaAges 30–55 - NCT05368987Recruiting
TMS for PTSD fear learning and safety memory
This study tests a brain-stimulation treatment called TMS to see if it improves how people with PTSD unlearn fear and form safer memories. It may help reduce fear responses by targeting specific fear-circuit areas in the brain.
Houston, TexasAges 18–70 - NCT05327504Recruiting
Writing therapy for PTSD and substance use in veterans
This study tests a structured “written exposure” therapy to help veterans with PTSD who also have a substance use disorder (SUD). It may help reduce PTSD symptoms while also supporting safer, more stable recovery.
West Haven, ConnecticutAges 18 years+ - NCT05310097Recruiting
CPT therapy program with memory support for PTSD veterans
This study tests a counseling approach called Cognitive Processing Therapy (CPT) with added memory support tools. It may help reduce PTSD symptoms while also supporting day-to-day memory challenges common in PTSD.
Jamaica Plain, MassachusettsAges 18 years+ - NCT05219175RecruitingPhase 2
MDMA therapy for PTSD and opioid addiction after childbirth
This Phase 2 study tests whether MDMA-assisted therapy can reduce symptoms of PTSD and help with opioid use disorder in people after childbirth. You must be on a stable, low enough dose of methadone or buprenorphine and be able to follow study rules, including therapy sessions and safety monitoring.
Albuquerque, New MexicoAges 18 years+ - NCT05156112Recruiting
Sleep apnea treatment for veterans with PTSD and substance use
This study tests whether treating sleep apnea with a breathing device during a residential program helps veterans with post-traumatic stress disorder (PTSD) and substance use problems. It aims to improve their recovery and quality of life.
San Diego, CaliforniaAges 18 years+ - NCT05149534Recruiting
Brain stimulation plus writing therapy for PTSD symptoms
This trial tests whether a type of brain stimulation (rTMS) combined with a structured writing therapy can reduce PTSD symptoms in veterans. It may help by boosting how the brain processes traumatic memories while you work through them in writing.
Temple, TexasAges 18–60 - NCT05133804RecruitingPhase 2
Testing two medications for PTSD attention and emotions
This Phase 2 study tests whether reboxetine or methylphenidate can improve attention and emotional or sensory problems in adults with post-traumatic stress disorder (PTSD). You may be eligible if you have a confirmed PTSD diagnosis and are able to meet medication and safety requirements.
AfulaAges 20–60 - NCT05120635Recruiting
Study brain signals tied to fear and anxiety in RNS patients
This study records electrical brain activity to understand how fear and anxiety work in people who already have an RNS (responsive neurostimulation) device placed. It may help researchers develop better ways to monitor and treat anxiety-related symptoms in the future.
Los Angeles, CaliforniaAges 18–70 - NCT04959695Recruiting
PE Coach app for veterans with PTSD therapy
This study tests whether a mobile app called “PE Coach” can support PTSD treatment (Prolonged Exposure therapy) for veterans. It may help you stay engaged with therapy sessions done in-person or by video/telehealth using a phone or tablet.
Seattle, WashingtonAges 18–65 - NCT04887116RecruitingEarly Phase 1
Virtual reality sessions to treat PTSD in healthcare workers
This early-phase study tests whether guided virtual reality experiences can reduce symptoms of PTSD (post-traumatic stress disorder) or near-PTSD in healthcare workers. It may help people who have stress reactions related to work during the COVID-19 era.
New York, New YorkAges 18 years+ - NCT04806620Recruiting
Online app study for brain inflammation lifestyle data
This study uses a digital platform (app/website) to collect lifestyle and symptom information to better understand brain inflammation. You may qualify if you have certain conditions like Long COVID, migraines, autoimmune disease, inflammatory gut issues, mood disorders, or if you are a healthy comparison person.
Delafield, WisconsinAges 2 years+
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Common questions
- Are there clinical trials for ptsd?
- Yes. Clin2 currently lists 296 recruiting ptsd studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ptsd trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ptsd trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.