Clinical trials
PTSD clinical trials
Below are recruiting ptsd clinical trials, each written for real people, not researchers. We’re tracking 292 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06876740Recruiting
Project Safe Guard-Trauma: A Study for Firearm Owners
This study tests a program to help firearm owners who have experienced trauma and may have PTSD. It aims to see if the program can improve safety and well-being.
Aurora, ColoradoAges 18 years+ - NCT06888128RecruitingPhase 2
Psilocybin for PTSD in veterans
This study tests whether a guided psilocybin session can help veterans heal from trauma-related PTSD. If you're a veteran with PTSD, you may be able to join.
Houston, TexasAges 21–64 - NCT06900712Recruiting
Single-session program for sexual assault recovery
This trial tests a one-time session designed to help survivors of unwanted sexual contact or assault reduce symptoms of PTSD or depression. It may be a good fit if you live in Ohio and have had these symptoms for at least a month.
Cleveland, OhioAges 18–65 - NCT06903819RecruitingPhase 4
Ketamine for pain and mental health after orthopedic injury
This trial tests if ketamine can reduce pain, opioid use, and improve mental health in adults recovering from serious orthopedic injuries. It may help those with high injury severity scores.
Lubbock, TexasAges 18–65 - NCT06937892Recruiting
Metacognitive therapy vs. Cognitive therapy for anxiety
This study compares two different types of therapy for anxiety disorders: metacognitive therapy (which focuses on how you think about your thoughts) versus cognitive-behavioral therapy (which works on changing thoughts and behaviors). It may help you find which approach works best for you.
StockholmAges 18 years+ - NCT06952933Recruiting
Trauma and resilience in adults with congenital heart disease
This study surveys adults with congenital heart disease to understand how psychological trauma and resilience affect their health. You would complete online questionnaires about your experiences and coping.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06957067Recruiting
PTSD Therapy Switch Study for Veterans
This study tests whether switching PTSD therapies or staying with one approach works better for veterans. It aims to reduce dropout and improve mental health outcomes.
Phoenix, ArizonaAges 18 years+ - NCT06975852Recruiting
Follow-up study on children after trauma
This study follows up on children who were seen one year ago after a traumatic event. Researchers want to see how they are doing now and if they need more support.
Istanbul, FatihAges 7–18 - NCT06989957RecruitingPhase 1
Psilocybin and MDMA therapy for PTSD in veterans
This study tests whether a combination of two investigational drugs, psilocybin and MDMA, can help veterans with post-traumatic stress disorder (PTSD). You would receive the drugs in a controlled setting and be monitored closely.
Baltimore, MarylandAges 21 years+ - NCT06990191Recruiting
Partner-assisted PTSD therapy study for veterans
This study tests whether having your partner help you with a type of talk therapy (prolonged exposure) can improve your PTSD symptoms more than doing the therapy alone. It is designed for veterans in a steady relationship whose partner does not have PTSD.
Phoenix, ArizonaAges 18 years+ - NCT07062042Recruiting
Empowering narratives for Ukrainian refugees in Norway
This study tests a therapy program for Ukrainian refugees in Norway who have PTSD symptoms or have experienced trauma. It aims to help participants by exploring personal stories and coping strategies.
OsloAges 18 years+ - NCT07071350RecruitingPhase 2/Phase 3
Optimizing heart rate for persistent concussion symptoms in military veterans
This trial tests a treatment designed to improve heart rate variability, which may help reduce long-term concussion symptoms like headaches, dizziness, and trouble sleeping. It is for military veterans who have had a mild concussion more than a year ago and still have ongoing symptoms.
Richmond, VirginiaAges 18 years+ - NCT07079761RecruitingPhase 2
PTSD treatment study with a hormone-like drug
This trial tests if a single infusion of allopregnanolone (a natural brain chemical) can help people with PTSD reduce fear responses and improve memory processing. It may offer a new way to treat PTSD by targeting how the brain stores traumatic memories.
Boston, MassachusettsAges 18–55 - NCT07079839Recruiting
Anxiety and stress study for adults with PTSD
This study looks at how the brain processes anxiety and stress in people with PTSD and healthy adults. It uses brain scans and mild electrical stimulation to understand these responses better.
Houston, TexasAges 18–50 - NCT07104916RecruitingPhase 2
Mindfulness and psilocybin therapy for PTSD
This study tests whether a combination of mindfulness training and a single dose of psilocybin can help reduce PTSD symptoms. It is for people with moderate-to-severe PTSD who are not on certain medications and do not have major health problems.
Columbus, OhioAges 21–65 - NCT07105345Recruiting
Cognitive processing therapy trial for PTSD
This trial tests a type of talk therapy called Cognitive Processing Therapy (CPT) to see if it helps people with post-traumatic stress disorder (PTSD). It aims to reduce PTSD symptoms and improve your daily life.
New Taipei City, Banqiao DistrictAges 20–65 - NCT07115030Recruiting
Support program for women with opioid use disorder and past abuse
This trial tests a stepped care program for women who have experienced intimate partner violence and are in treatment for opioid use disorder. It aims to improve recovery by addressing post-traumatic stress symptoms and overall well-being.
Bridgeport, ConnecticutAges 18 years+ - NCT07118839RecruitingPhase 2/Phase 3
MDMA therapy for veterans with PTSD and alcohol use
This study tests whether MDMA-assisted therapy can help veterans who have both PTSD and alcohol use disorder. If you have tried a standard therapy before and want to reduce or stop drinking, this treatment may offer a new option.
West Haven, ConnecticutAges 18 years+ - NCT07121270Recruiting
Sleep treatment after trauma in the ER
This study tests a sleep-focused treatment for people who have experienced a violent trauma (like an assault) in the past few days and are at risk for mental health problems. The goal is to help improve sleep and reduce distress after a traumatic event.
Detroit, MichiganAges 18 years+ - NCT07193914Recruiting
Program for people with addiction and trauma
This trial tests a program called ECCCLORE to help people who struggle with both addiction and trauma. It aims to see if the program can improve their well-being.
Nîmes, NîmesAges 18 years+ - NCT07197476Recruiting
Helping teens after a traumatic injury
This study tests a program to help teens who have been in the hospital for a traumatic injury. It aims to reduce stress and substance use by offering a supportive intervention.
Providence, Rhode IslandAges 12–17 - NCT07214415RecruitingPhase 2
Hyperbaric oxygen therapy for veterans with brain injury or mental health issues
This trial tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can improve thinking, mood, and quality of life in veterans with mild traumatic brain injury, PTSD, anxiety, or depression. You must have already tried at least one evidence-based therapy like CBT or EMDR.
Boise, IdahoAges 18–75 - NCT07217795Recruiting
Recovery group for LGBTQ+ mental health and substance use
This trial is testing a new type of talk therapy program designed to help sexual minority women and transgender/gender diverse people recover from mental health and substance use challenges. It focuses on learning coping skills, building self-confidence, solving problems, and finding community support.
Providence, Rhode IslandAges 18 years+ - NCT07245641Recruiting
Targeted brain stimulation for PTSD
This trial tests a new form of brain stimulation (called targeted accelerated TMS) to see if it can help reduce symptoms of post-traumatic stress disorder (PTSD). It involves daily sessions over a short period and may be an option if you have at least moderate PTSD symptoms and a stable treatment plan.
Boston, MassachusettsAges 18–65
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Common questions
- Are there clinical trials for ptsd?
- Yes. Clin2 currently lists 292 recruiting ptsd studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ptsd trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ptsd trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.