Clinical trials
Post-Traumatic Stress clinical trials
Below are recruiting post-traumatic stress clinical trials, each written for real people, not researchers. We’re tracking 143 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07703722RecruitingPhase 3
Psilocybin and therapy for depression with trauma
This trial tests psilocybin (a compound from certain mushrooms) combined with a structured therapy to see if it helps people with depression linked to trauma. It focuses on how the treatment affects the connection between the gut and brain.
Islamabad, CapitalAges 18–60 - NCT04152993RecruitingEarly Phase 1
Brain stimulator study for chronic, hard-to-treat PTSD
This early-phase study tests a responsive brain stimulation device to help people with chronic PTSD who have not improved with standard treatments. You would be closely followed for years, with regular assessments and device setting changes to see if symptoms improve.
Los Angeles, CaliforniaAges 25–60 - NCT04180930Recruiting
Comparing two PTSD screening tests
This study compares two different questionnaires doctors use to assess PTSD (post-traumatic stress disorder) symptoms. If you’ve had a traumatic event and currently have PTSD symptoms, it may help improve how PTSD is identified in active-duty service members and veterans.
Honolulu, HawaiiAges 18 years+ - NCT04276922Recruiting
Creative arts program to reduce healthcare burnout
This study tests a creative arts program to help reduce burnout symptoms in people who work in hospitals. If you’re feeling emotionally drained or disconnected at work, participating may help you build coping and well-being skills.
Aurora, ColoradoAges 18–85 - NCT04426448Recruiting
Test a short PTSD talk therapy for people in Botswana
This study tests a brief counseling intervention for people who have PTSD symptoms. It aims to see if a short, structured approach can help reduce PTSD symptoms for adults in Botswana.
LobatseAges 18 years+ - NCT04585685Recruiting
Healthy recovery program for PTSD after sexual trauma
This study looks at how to help people recover from PTSD symptoms after sexual trauma, including feeling mentally “contaminated.” You may be eligible if you currently meet criteria for PTSD and report these contamination feelings, and you can avoid starting other trauma treatments during the study.
Lexington, KentuckyAges 18 years+ - NCT04626050Recruiting
PTSD and stress support study for healthcare workers
This study looks at psychological distress, including post-traumatic stress disorder (PTSD), in healthcare workers after work-related trauma. You may be eligible if you are an adult healthcare worker with PTSD (and otherwise stable) who can complete regular study check-ins.
New York, New YorkAges 18 years+ - NCT04701723Recruiting
Breathing training to help after trauma stress
This pilot study tests whether “cardiac coherence” breathing exercises can help prevent ongoing (chronic) post-traumatic stress disorder after a recent traumatic event. It’s meant for people who are newly dealing with an acute stress reaction, soon after the event.
Saint-PaulAges 18 years+ - NCT04793776Recruiting
MERA program to reduce aggression in PTSD
This trial tests a program called MERA to help people with PTSD-related symptoms manage emotions and reduce aggressive outbursts. It’s meant for Veterans who’ve had recent impulsive aggression and may benefit from structured skills practice and coaching.
Tampa, FloridaAges 18–64 - NCT04852744Recruiting
Brain scan study in teens with borderline and/or PTSD
This study uses brain imaging (MRI) to compare brain patterns in teens with borderline personality disorder and those with PTSD, as well as teens without these mental health diagnoses. It may help researchers understand what brain differences go along with these conditions and how they relate to each other.
CaenAges 13–18 - NCT05663034Recruiting
Compare CBT-I vs MBTI for sleep and trauma symptoms after TBI
This study compares two types of talk-based therapy to help veterans with long-lasting insomnia after a traumatic brain injury (TBI), and also looks at related post-trauma stress symptoms. It may help you improve sleep and reduce how much these symptoms affect daily life.
Eglin Air Force Base, FloridaAges 18 years+ - NCT04953273Recruiting
Case management support for adult women after violence
This study tests an organized “case management” plan for adult women who seek medical/forensic help after experiencing serious violence or threats. The goal is to improve how support and next steps are organized after the incident.
AmiensAges 18 years+ - NCT04985344RecruitingPhase 3
Propranolol to treat PTSD symptoms in children using memory reactivation
This trial studies whether propranolol (a heart-related medicine) can help children with post-traumatic stress disorder (PTSD) after a special memory-activation session. The goal is to reduce PTSD symptoms compared with the comparison condition.
ToulouseAges 7–12 - NCT05219175RecruitingPhase 2
MDMA therapy for PTSD and opioid addiction after childbirth
This Phase 2 study tests whether MDMA-assisted therapy can reduce symptoms of PTSD and help with opioid use disorder in people after childbirth. You must be on a stable, low enough dose of methadone or buprenorphine and be able to follow study rules, including therapy sessions and safety monitoring.
Albuquerque, New MexicoAges 18 years+ - NCT05240924Recruiting
Exposure therapy program for veterans with OCD and PTSD
This study tests whether a structured therapy approach called Exposure and Response Prevention (ERP) can improve functioning in veterans with OCD, with or without PTSD. You may be eligible if you’re receiving care through certain VA clinics or telehealth hubs and are willing to take part in ERP.
East Orange, New JerseyAges 18 years+ - NCT05244564Recruiting
PTSD app treatment comparison: monitor vs AR 3MDR
This trial tests whether two different ways of delivering an “AR 3MDR” PTSD therapy work better than a standard computer monitor approach. You may be eligible if you have PTSD and can do the required walking session on a treadmill safely.
Bethesda, MarylandAges 18 years+ - NCT05331534Recruiting
Attentional therapy for PTSD symptoms after trauma
This trial studies whether a therapy focused on attention can reduce post-traumatic stress disorder (PTSD) symptoms. You may qualify if you have PTSD diagnosed by standard questionnaires and interviews, and if you can safely take part in the therapy sessions.
LilleAges 18–60 - NCT05358067Recruiting
Testing a symptom rating tool after recent trauma
This study looks at how well a clinician’s rating scale (a questionnaire-based score) matches patients’ symptoms after a traumatic event. It may help improve how quickly and accurately symptoms are tracked in the days after trauma.
ArrasAges 18 years+ - NCT05414708Recruiting
Art therapy for veterans with PTSD symptoms
This study tests whether art therapy can improve emotional well-being in military members who have significant PTSD symptoms. You would answer questionnaires and likely take part in art-making sessions as part of the treatment being studied.
Bethesda, MarylandAges 18–64 - NCT05441280RecruitingPhase 2
Pimavanserin to improve sleep in veterans with PTSD
This Phase 2 trial studies pimavanserin, a medicine meant to improve insomnia, in veterans who also have PTSD. It may help reduce problems with falling asleep, staying asleep, or waking too early that affect daytime functioning.
Houston, TexasAges 18–64 - NCT05491538Recruiting
Work skills training for Veterans living with serious mental illness
This study tests whether a social-skills training program designed for work goals is doable and helpful for Veterans with serious mental illness. It focuses on improving work-related coping and interactions while you receive supported services through the VA.
Minneapolis, MinnesotaAges 18 years+ - NCT05517304Recruiting
Noninvasive vagus nerve stimulation for PTSD symptoms
This trial tests whether a noninvasive device that stimulates the vagus nerve through the skin can reduce PTSD symptoms in veterans. It may help calm stress responses without requiring surgery.
Decatur, GeorgiaAges 18–75 - NCT05560113Recruiting
Study uses brain stimulation to disrupt fear memory in PTSD
This study tests a brain stimulation approach to affect how fear memories “stick” after they are formed. If you have PTSD, it may help reduce fear-related learning, but you must meet several safety and health criteria.
Atlanta, GeorgiaAges 18–65 - NCT05637879RecruitingPhase 2/Phase 3
Glecaprevir for PTSD symptoms in Veterans
This Phase 2/3 study tests whether glecaprevir/pibrentasvir can reduce post-traumatic stress disorder (PTSD) symptoms. It may help Veterans whose PTSD is still affecting daily life, alongside any allowed standard care.
White River Junction, VermontAges 19–70
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Common questions
- Are there clinical trials for post-traumatic stress?
- Yes. Clin2 currently lists 143 recruiting post-traumatic stress studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a post-traumatic stress trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a post-traumatic stress trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.