Clinical trials
Post-Traumatic Stress clinical trials
Below are recruiting post-traumatic stress clinical trials, each written for real people, not researchers. We’re tracking 150 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06903819RecruitingPhase 4
Ketamine for pain and mental health after orthopedic injury
This trial tests if ketamine can reduce pain, opioid use, and improve mental health in adults recovering from serious orthopedic injuries. It may help those with high injury severity scores.
Lubbock, TexasAges 18–65 - NCT06852469RecruitingPhase 4
GABA test for PTSD in veterans
This trial uses a medication called lorazepam to study how GABA receptors work in veterans with PTSD. It aims to learn more about brain chemistry related to PTSD and how it might affect treatment.
San Diego, CaliforniaAges 18–65 - NCT06854328Recruiting
Prism PTSD study for adolescents
This trial tests a new non-invasive device that uses brain imaging to help treat PTSD symptoms in teens and young adults. It may be a good option if you haven't yet completed a full course of trauma-focused therapy.
New York, New YorkAges 12–21 - NCT06823024Enrolling by invitation
Using speech patterns to predict treatment response in depression, PTSD, or bipolar disorder
This study tests if a computer algorithm can analyze your speech to predict how well you will respond to treatments like TMS or Spravato. It aims to create a simple tool that helps doctors choose the right treatment for you.
Sunnyvale, CaliforniaAges 18–68 - NCT05244564Recruiting
PTSD app treatment comparison: monitor vs AR 3MDR
This trial tests whether two different ways of delivering an “AR 3MDR” PTSD therapy work better than a standard computer monitor approach. You may be eligible if you have PTSD and can do the required walking session on a treadmill safely.
Bethesda, MarylandAges 18 years+ - NCT04852744Recruiting
Brain scan study in teens with borderline and/or PTSD
This study uses brain imaging (MRI) to compare brain patterns in teens with borderline personality disorder and those with PTSD, as well as teens without these mental health diagnoses. It may help researchers understand what brain differences go along with these conditions and how they relate to each other.
CaenAges 13–18 - NCT06770998Recruiting
EEG brain training for PTSD
This study tests a new kind of treatment for PTSD that uses a special brain training system called neurofeedback. You will learn to change your own brain activity in sessions that use EEG sensors on your head, and the goal is to reduce your PTSD symptoms without medication or talk therapy.
Birmingham, AlabamaAges 18–65 - NCT04426448Recruiting
Test a short PTSD talk therapy for people in Botswana
This study tests a brief counseling intervention for people who have PTSD symptoms. It aims to see if a short, structured approach can help reduce PTSD symptoms for adults in Botswana.
LobatseAges 18 years+ - NCT06723834Enrolling by invitation
Service Dogs and PTSD Therapy for Military Members
This study tests if pairing a psychiatric service dog with a type of talk therapy helps military-connected people with PTSD. It’s for those who have been approved to get a service dog and are not already in the same therapy.
Tucson, ArizonaAges 18 years+ - NCT06706882Enrolling by invitation
Thinking and memory in women who have experienced partner violence
This study looks at how thinking skills like planning and memory are affected in women who have survived intimate partner violence. It may help explain how these experiences affect daily life and mental health.
Granada, GranadaAges 18–50 - NCT06690151Recruiting
Babies with heart defects and development support
This study looks at how a serious heart condition before birth may affect a baby's brain development. It follows babies and their parents to better understand and support these children as they grow.
Nantes, Loire AtlantiqueAges Any age - NCT06636786RecruitingPhase 2
Medication to reduce stress symptoms after a car accident
This study tests whether a medication placed under the tongue can help prevent or reduce stress-related symptoms, like anxiety or post-traumatic stress, after a motor vehicle crash. It may help you feel better in the weeks following the accident.
Birmingham, AlabamaAges 18–55 - NCT06629064Recruiting
Memory training for PTSD symptoms
This study tests a computer-based memory training program for people with PTSD. It aims to see if this training can help reduce PTSD symptoms by improving how your brain processes memories. The study involves 8 remote sessions over 4 weeks and two MRI scans to look at brain changes.
San Diego, CaliforniaAges 18–65 - NCT05331534Recruiting
Attentional therapy for PTSD symptoms after trauma
This trial studies whether a therapy focused on attention can reduce post-traumatic stress disorder (PTSD) symptoms. You may qualify if you have PTSD diagnosed by standard questionnaires and interviews, and if you can safely take part in the therapy sessions.
LilleAges 18–60 - NCT06589505RecruitingPhase 2/Phase 3
Software app for treating PTSD
This trial is testing a software program (like an app) designed to help treat PTSD. It may be an option if your PTSD is related to a past traumatic event and you haven't already tried several trauma-focused therapies.
Yamanashi, HokkaidoAges 18–65 - NCT06592677Recruiting
Early support after trauma
This trial tests if early support from a municipal crisis team can help people who have been through a traumatic event. It may be a good option if you have symptoms of post-traumatic stress and want to see if extra support soon after the event can help you feel better.
Asker, AskerAges 16–99 - NCT06577636RecruitingPhase 2
Dreaming with anesthesia for post-traumatic stress disorder
This study tests whether using anesthesia to induce dreaming can help people with post-traumatic stress disorder (PTSD). It aims to see if a therapy session under anesthesia can reduce PTSD symptoms and improve well-being.
Stanford, CaliforniaAges 18–70 - NCT06538246Recruiting
Coping skills training for heart and lung failure survivors
This study tests a coping skills training program to help people who recently survived a serious heart or lung problem feel less anxious, depressed, or stressed. If you were in the ICU and now feel distressed at home, you may be able to join.
Durham, North CarolinaAges 18 years+ - NCT05889741RecruitingPhase 2
Stellate nerve block plus prolonged therapy for PTSD symptoms
This Phase 2 study tests whether a procedure called a stellate ganglion block, combined with prolonged exposure therapy, can reduce PTSD symptoms in military members. It may help by targeting the body’s stress signaling while you work on trauma-related memories with guided therapy.
Fort Hood, TexasAges 18–65 - NCT06516874Recruiting
Trauma-focused therapy for PTSD in adults
This study tests a therapy called trauma-focused cognitive-behavioral therapy (TF-CBT) for adults with PTSD or complex PTSD. It aims to see if this approach can help people who have been through traumatic events feel better.
Curicó, Maule RegionAges 18–64 - NCT06521398Recruiting
Postpartum Care for Preterm NICU Babies
This study focuses on helping new mothers of preterm babies (born before 34 weeks) who are getting care in the NICU at HUP. It tests a program to support your transition home after giving birth, so you and your baby can thrive.
Philadelphia, PennsylvaniaAges 16 years+ - NCT06477796Recruiting
Improving sleep in veterans with TBI and sleep problems
This study tests a new way to help Veterans with both a traumatic brain injury (TBI) and sleep problems get better rest. If you are a Veteran with sleep trouble and a history of TBI, this program may help improve your sleep without needing extra medication.
Portland, OregonAges 18–89 - NCT06479447Recruiting
Patient-reported PTSD screening study
This trial is testing a simple way to check for PTSD symptoms using patient-reported questionnaires. It aims to help people who haven't been screened recently get the care they need.
Chicago, IllinoisAges 18 years+ - NCT06419959Recruiting
NightWare app for veterans with PTSD and sleep problems
This study tests a smartwatch app called NightWare that may reduce nightmares and improve sleep in veterans with PTSD. It could also help heart health by improving sleep quality.
Aurora, ColoradoAges 22–88
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Common questions
- Are there clinical trials for post-traumatic stress?
- Yes. Clin2 currently lists 150 recruiting post-traumatic stress studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a post-traumatic stress trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a post-traumatic stress trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.