Clinical trials
Post-Treatment Lyme Disease clinical trials
Below are recruiting post-treatment lyme disease clinical trials, each written for real people, not researchers. We’re tracking 10 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04806620Recruiting
Online app study for brain inflammation lifestyle data
This study uses a digital platform (app/website) to collect lifestyle and symptom information to better understand brain inflammation. You may qualify if you have certain conditions like Long COVID, migraines, autoimmune disease, inflammatory gut issues, mood disorders, or if you are a healthy comparison person.
Delafield, WisconsinAges 2 years+ - NCT05776251Recruiting
Noninvasive nerve stimulation for ongoing Lyme symptoms
This trial tests whether taVNS (a noninvasive nerve stimulation done through the skin near the ear) can reduce long-lasting symptoms after Lyme disease. It targets people whose symptoms have stayed for months after standard antibiotic treatment.
New York, New YorkAges 18–65 - NCT06026969Recruiting
Study on Lyme disease and baby development after pregnancy exposure
This study looks at how Lyme disease during pregnancy might affect a baby's development. It involves questionnaires and possibly an MRI of the baby's brain, done at a visit or remotely.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06511050RecruitingPhase 1/Phase 2
Testing Lumbrokinase for Long COVID, Lyme, and Chronic Fatigue
This trial tests a supplement called Lumbrokinase (derived from earthworms) to see if it helps reduce symptoms in people with Long COVID, post-treatment Lyme disease syndrome, or ME/CFS. It may benefit those whose daily life is significantly affected by these conditions.
New York, New YorkAges 18 years+ - NCT06611111RecruitingEarly Phase 1
Ceftriaxone for lingering fatigue after Lyme disease
This study tests whether a short course of a strong antibiotic (ceftriaxone) can help people who still have fatigue and other symptoms after being treated for Lyme disease. It aims to see if this treatment can improve your quality of life.
East Syracuse, New YorkAges 18–75 - NCT06655844Recruiting
Sana Device for chronic pain from Lyme disease
This study tests the Sana device—a special light and sound tool—to see if it can help reduce chronic nerve pain in people with Post-Treatment Lyme Disease Syndrome. You may be able to join if you have ongoing nerve pain after Lyme treatment and meet a few basic health and medication rules.
New York, New YorkAges 18 years+ - NCT06915324Recruiting
Electric brain stimulation for Lyme disease cognitive issues
This study tests if a gentle electrical current applied to the scalp can improve thinking problems (like slow processing speed) that continue after Lyme disease treatment. It could help you if you have mental fog or memory trouble that hasn't gone away with antibiotics.
San Francisco, CaliforniaAges 18–70 - NCT00001539Recruiting
Understanding Symptoms After Lyme Disease Treatment
This research study examines why some people continue to have symptoms months after being treated for Lyme disease. Researchers will compare patients with ongoing symptoms to people who recovered well, to better understand what causes lasting problems and how to help.
Bethesda, MarylandAges 13–99 - NCT05552157RecruitingPhase 2/Phase 3
Study of treatments for early onset Alzheimer's caused by genetic mutations
This trial tests potential treatments for people who are at risk for or have early onset Alzheimer's disease due to a specific genetic mutation. It aims to find treatments that could slow or prevent symptoms.
Birmingham, AlabamaAges 18 years+ - NCT06647498RecruitingPhase 2/Phase 3
Study of a treatment for early-onset Alzheimer's caused by a gene change
This study tests a potential disease-modifying treatment for people who have a specific gene mutation that causes early-onset Alzheimer's disease. The goal is to see if the treatment can delay or prevent symptoms.
Birmingham, AlabamaAges 18 years+
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Post-Treatment Lyme Disease trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for post-treatment lyme disease?
- Yes. Clin2 currently lists 10 recruiting post-treatment lyme disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a post-treatment lyme disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a post-treatment lyme disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.