Clinical trials
Postpartum Depression clinical trials
Below are recruiting postpartum depression clinical trials, each written for real people, not researchers. We’re tracking 73 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07066631Recruiting
Online mental health support for pregnant and new parents
This trial tests a virtual program to help pregnant people and new parents with depression or anxiety. It provides mental health support through online tools and care coordination.
Toronto, OntarioAges 18 years+ - NCT06445933Recruiting
Vitamin B6 for depression in pregnancy and after birth
This trial tests whether taking Vitamin B6 can help prevent depression in pregnant women and new mothers. If you are between 24 and 28 weeks pregnant and have no history of mental health conditions, you may be able to join.
TaipeiAges 20–50 - NCT06772701Recruiting
French depression screening test for new fathers
This study checks if a questionnaire used to spot postpartum depression in mothers also works well for fathers after their baby is born. It is only for French-speaking dads with a newborn up to 10 days old.
ClamartAges 18 years+ - NCT07302165Enrolling by invitation
Online tool to screen and prevent postpartum depression in parents-to-be
This trial tests a digital tool to find and help parents at risk for depression after childbirth. You may qualify if you have certain thinking patterns or risk factors during pregnancy.
CopenhagenAges 18 years+ - NCT07064928Enrolling by invitation
Reducing HIV stigma in pregnancy and after birth
This study tests a program to reduce stigma related to HIV among pregnant women and new mothers. You may be eligible if you are living with HIV, are between 24 and 36 weeks pregnant, and plan to stay in the area for at least 6 months after your baby is born.
AccraAges 14 years+ - NCT04821544Recruiting
Study of stress in new mothers and how it affects breastmilk
This study looks at how stress in new mothers may change their breastmilk and how that relates to newborn health outcomes. It is specifically recruiting mothers with babies in certain NICUs.
Coeur d'Alene, IdahoAges 18–50 - NCT05700760Recruiting
ROSE program study to prevent postpartum depression
This study tests whether a program called ROSE can help prevent postpartum depression after delivery. If you’re pregnant, you may be asked to complete questionnaires and be reached by phone for study steps.
Flint, MichiganAges 18 years+ - NCT06175104Recruiting
HeartGPS: Support for parents after a prenatal heart diagnosis
This study tests a counseling program for parents whose unborn baby has a serious heart condition called single ventricle. The program aims to help parents manage stress and support their baby's development before and after birth.
Los Angeles, CaliforniaAges 18 years+ - NCT06246214Recruiting
Biological rhythms for perinatal mental health
This study looks at whether understanding your body's daily rhythms (like sleep and activity) can help treat depression after childbirth. If you are 4-6 weeks postpartum and have been diagnosed with postnatal depression, this could be an option for you.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06275217Recruiting
Mindful yoga for new mothers with low mood
This study tests if a mindful yoga program can help new mothers with symptoms of postpartum depression. If you are feeling down after giving birth and are willing to try gentle yoga and mindfulness, this may be a good option for you.
Hong KongAges 18–60 - NCT06379074Recruiting
Sleep in pregnancy and postpartum mental health
This study looks at how poor sleep during pregnancy might affect stress and mental health after childbirth. It aims to help new mothers by understanding these links.
Bologna, BolognaAges 18 years+ - NCT06462638Recruiting
Contact and relationship in the NICU for preterm babies
This study looks at how contact and relationship-building between parents and their babies in the neonatal intensive care unit (NICU) can help. It is for babies born a bit early (33–36 weeks) who are now stable, and for their parents under 50.
MessinaAges 18–50 - NCT06512025Recruiting
Education program for first-time new mothers
This study tests whether a short education program (psychoeducational intervention) can help new first-time moms feel more confident and supported after childbirth. If you qualify, you would receive extra information and guidance during your postpartum checkups.
Barcelona, BarcelonaAges 18 years+ - NCT06737055Recruiting
Sleep help for new and expectant parents
This study tests a sleep program for pregnant women and new moms. It uses specially trained helpers to teach better sleep habits, which may improve your rest and well-being.
Providence, Rhode IslandAges 18–99 - NCT06788977Recruiting
Migraine treatment in pregnancy with a nerve stimulation device
This trial tests if a device that gently stimulates a nerve on your forehead can safely treat migraines during pregnancy. You'll use the device at home and track your headaches via text or email.
Darien, ConnecticutAges 18–44 - NCT07214597Recruiting
Using voice technology to improve NICU mom experience
This trial tests a smartphone app called VoiceLove that lets moms record their voice for their baby in the NICU. It may help mothers feel more connected and supported while their baby is in the hospital.
Nashville, TennesseeAges 18 years+ - NCT07440355Enrolling by invitation
Light therapy for postpartum depression and baby development
This study looks at how light therapy for mothers with postpartum depression might affect their baby's development. It involves babies born to mothers who are already part of a larger postpartum depression treatment study.
Porto Alegre, Rio Grande do SulAges Any age - NCT07223736Recruiting
AI education for new mothers after birth
This study tests an AI-based education tool for first-time mothers to help with recovery and reduce loneliness after childbirth. You participate from home using your smartphone for 2-6 weeks after delivery.
La Jolla, CaliforniaAges 18 years+ - NCT06557005Recruiting
Helping new mothers with chronic conditions get primary care
This study helps new mothers with chronic health conditions transition smoothly from pregnancy care to regular primary care. If you have high blood pressure, diabetes, severe obesity, depression, or anxiety, you may be able to join a program that coordinates your care after childbirth.
Boston, MassachusettsAges 18 years+ - NCT07413692Recruiting
Device therapy for depression and urinary incontinence after childbirth
This study tests two devices to help with depressive symptoms and urinary incontinence in women who gave birth 2–60 months ago. It aims to see if the treatments can improve how you feel and bladder control without using medication.
Garfield Heights, OhioAges 22–60 - NCT07561632Recruiting
Early Stress Screening After Emergency Cesarean Delivery
This study looks at whether certain signs of distress right after an unexpected cesarean delivery can predict who might develop PTSD (post-traumatic stress disorder) later. Researchers want to understand this connection so they can help women who are struggling after this traumatic birth experience.
Vancouver, British ColumbiaAges 19 years+ - NCT07376369Recruiting
Spousal support and parenting confidence in new mothers
This study looks at how support from a spouse affects the confidence and mood of first-time mothers. Participants will answer online questionnaires about their experiences.
IstanbulAges 18 years+ - NCT05897619Recruiting
CBT skills app for pregnancy and postpartum stress and coping
This study tests whether a new phone app that teaches “cognitive behavioral therapy” (CBT) skills is helpful and easy to use for people who are pregnant or recently gave birth. It also checks safety and whether participants feel the app is acceptable to use over time.
New York, New YorkAges 18 years+ - NCT05624931Recruiting
Helping pregnant women stay on PrEP after starting it
This study tries to reduce the psychological barriers that make it hard for pregnant or postpartum women to keep taking PrEP. It may help by offering support tailored to stress, trauma symptoms, or depression—especially soon after PrEP is started.
Boston, MassachusettsAges 15 years+
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Common questions
- Are there clinical trials for postpartum depression?
- Yes. Clin2 currently lists 73 recruiting postpartum depression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postpartum depression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postpartum depression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.