Clinical trials
Premature clinical trials
Below are recruiting premature clinical trials, each written for real people, not researchers. We’re tracking 264 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07232069RecruitingPhase 3
Early heart disease trial for women and men with mild plaque buildup
This trial tests whether two medicines, a statin and colchicine, can slow or stop early heart artery plaque from growing in people who have mild plaque but no heart disease symptoms yet. It uses special CT scans to measure plaque over 2 years.
Birmingham, AlabamaAges 30–60 - NCT06731439Recruiting
Starting feeds on day 1 for very small premature babies
This study is for very premature babies (weighing about 2 pounds or less) to see if starting small feedings on the first day of life helps them reach full feeds sooner. If your baby is very small and otherwise healthy, this option may help them grow faster.
Memphis, TennesseeAges 1 minute–6 hours - NCT07031531Recruiting
AI heart health program for young adults
This study tests if an AI-powered system can help manage premature coronary artery disease in adults aged 18 to 45. It uses a smartphone app to support treatment and improve outcomes.
Hefei, AnhuiAges 18–45 - NCT07076771Recruiting
Testosterone and artery blockage in young men with heart disease
This study looks at whether testosterone levels are linked to how blocked the heart arteries are in young men (under 45) with early heart disease. It involves a one-time blood test during a planned cardiac catheterization.
SohagAges Up to 45 years - NCT06164730RecruitingPhase 1
Study of VERVE-102 for high cholesterol or early heart disease
This trial tests a new medicine called VERVE-102 for people with a specific type of high cholesterol (HeFH) or early coronary artery disease. It aims to see if it can help lower cholesterol levels.
Dothan, AlabamaAges 18–70 - NCT07732257Recruiting
Wireless button sensor study for premature infants
This study tests a small, wireless button-like sensor to monitor vital signs in premature infants in the NICU. It may offer a gentler way to track your baby's health.
Montreal, QuebecAges Any age - NCT07715682Recruiting
Gentle touch and calm for premature babies' blood tests
This study tests whether gentle human touch and fewer distractions can help reduce pain and improve comfort for premature babies during a standard heel-prick blood test.
AnkaraAges 7 months–9 months - NCT00346814RecruitingPhase 2/Phase 3
Bevacizumab injections for severe eye vessel disease in premature babies
This trial studies whether an anti–blood vessel medicine (bevacizumab, given by eye injection) can improve the structure of the retina in very premature babies with advanced retinopathy of prematurity. It may help when standard treatments like laser or freezing cannot be used.
Mexico City, Mexico DFAges 1 month–1 year - NCT03083431RecruitingPhase 2
Oral propranolol to prevent early retinopathy in preemies
This trial tests whether giving propranolol by mouth to certain very premature babies with early eye changes can stop retinopathy of prematurity from getting worse. It may help reduce the need for eye treatments later on.
Tübingen, Baden-WurttembergAges 1 month–3 months - NCT03825835Recruiting
Different oxygen levels at birth for very preterm babies
This trial studies whether giving 30% versus 60% oxygen during early resuscitation (breathing support) affects brain and nerve development in very low birthweight, very preterm infants. If you/your baby fits the birth and care timing requirements, the goal is to find an oxygen approach that supports better long-term outcomes.
Calgary, AlbertaAges birth–10 minutes - NCT07701759Recruiting
Oxygen levels during eye injections for premature babies
This study looks at how often low oxygen levels happen in premature babies when they get eye injections for a serious eye condition. The goal is to understand the risks and make the procedure safer.
BuraidahAges Any age - NCT04047849RecruitingPhase 4
Antibiotics for early water breaking before 23 weeks
This trial studies whether taking antibiotics can help in pregnancies where the “water” broke early (before 23 weeks) but you don’t have a fever. It aims to reduce complications while keeping both mother and baby as safe as possible.
Baton Rouge, LouisianaAges 18 years+ - NCT04167033Recruiting
Checking heart rhythm timing in women with premature ovarian insufficiency
This study measures how quickly the heart “recharges” between beats (often shown as QT timing). It compares women with premature ovarian insufficiency to healthy women to understand whether ovarian insufficiency is linked to heart rhythm differences.
BordeauxAges 18–40 - NCT04439370Recruiting
Blood pressure control study in women with early menopause
This study looks at how the body automatically regulates blood pressure in women who went through menopause earlier than expected. It may help researchers understand whether early menopause affects blood pressure control and related health risks.
Minneapolis, MinnesotaAges 35–70 - NCT04617717Recruiting
Personalized treatment for abnormal heartbeats needing ablation
This trial studies a customized treatment plan for people who have premature ventricular beats (PVCs) and have been referred for a procedure called PVC ablation. It may help doctors choose the best approach for stopping these extra heartbeats.
OsloAges 18–90 - NCT04939571Recruiting
Registry for babies with retinopathy of prematurity
This study is a European registry that collects medical information (stored electronically) about babies who have retinopathy of prematurity (ROP) severe enough to need treatment. It may help doctors understand outcomes and improve care by tracking real-world results.
SalzburgAges Any age - NCT04995341Recruiting
School-age follow-up study for premature babies’ eye health
This study looks at eye structure in children who were in an earlier premature-baby eye study and are now around 4.5–5 years old. It may help researchers better understand how eye disease in prematurity develops and how to monitor it.
Durham, North CarolinaAges Any age - NCT05264779Recruiting
Decision help tool for very early delivery planning
This study tests a decision-support tool (a structured way to guide conversations) for parents facing a high risk of delivering very early (about 22–26 weeks). It may help you and your baby’s care team make clearer, more aligned choices about neonatal (newborn) treatment.
San Diego, CaliforniaAges 18 years+ - NCT05340582RecruitingPhase 2
Ibuprofen plus acetaminophen for a heart condition in very premature babies
This Phase 2 study tests whether giving ibuprofen together with acetaminophen improves outcomes for an important heart connection (PDA) in extremely premature infants. It compares how this medicine approach affects the baby’s heart-related measurements and short-term progress.
Newcastle, New South WalesAges Up to 6 months - NCT06072625Recruiting
Olive oil supplement for premature babies fed by tube
This trial tests whether adding olive oil to the tube feedings of premature babies helps them grow and develop better. It may be an option for babies born at 32 weeks or less who are tolerating full feedings early on.
BursaAges 2 weeks–1 month - NCT05989438Recruiting
Different therapy models for premature babies based on the ICF biopsychosocial model
This trial compares different therapy approaches for premature babies. It aims to help with their development using the ICF biopsychosocial model, which looks at health from many angles.
Porto Alegre, Rio Grande do SulAges 4 months–2 years - NCT06048614Recruiting
Saline enema for meconium blockage in premature babies
This trial tests if giving a saline enema helps premature babies with meconium blockage pass stool, start feeding, and improve gut and brain health. It may reduce complications and help babies grow better.
SingaporeAges 1 day–8 months - NCT06067529Recruiting
Study on the health effects of early menopause
This study follows women with premature ovarian insufficiency (POI) over time to understand how it affects their health. Researchers will collect samples and track health changes to learn more about the condition and its long-term effects.
Hangzhou, ZhejiangAges 10–65 - NCT06067958RecruitingPhase 3
Nose spray medicine for pain during eye exams in preemies
This study tests a nose spray medicine (dexmedetomidine) to help reduce pain and discomfort in premature babies who need eye exams for retinopathy of prematurity (a condition that can affect vision). The goal is to see if the spray works better than the usual care for calming babies during the exam.
Be’er Ya‘aqov, CenterAges 4 weeks+
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Common questions
- Are there clinical trials for premature?
- Yes. Clin2 currently lists 264 recruiting premature studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a premature trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a premature trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.