Clinical trials
Probiotic clinical trials
Below are recruiting probiotic clinical trials, each written for real people, not researchers. We’re tracking 222 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07148583Recruiting
BioAmicus Complete for tummy troubles in babies
This study tests if a probiotic supplement called BioAmicus Complete can help babies with common digestive issues like colic, reflux, constipation, or loose stools. It might be a good option if your baby has these symptoms and you haven't used other probiotics or antibiotics recently.
Haiphong, Hai PhongAges birth–2 years - NCT07154992Recruiting
Preventing colds in kids with a probiotic
This trial tests if a daily probiotic (Lacticaseibacillus rhamnosus CRL1505) can help prevent upper respiratory infections (like colds and sore throats) in healthy children ages 3 to 12. If your child often gets sick, this supplement might reduce how often they catch a cold.
MurciaAges 3–12 - NCT07182890RecruitingPhase 4
Probiotic for anxiety and depression in functional dyspepsia
This trial tests whether a probiotic called Clostridium Butyricum can help reduce anxiety and depression in people with functional dyspepsia (a type of stomach discomfort without a clear cause). If you have mild to moderate anxiety or depression along with your stomach symptoms, this study may offer a potential new treatment option.
Xi’an, ShanxiAges 18–80 - NCT07187492RecruitingPhase 4
Can a probiotic ease anxiety and depression in functional dyspepsia?
This trial tests whether a probiotic called Bacillus coagulans can help reduce anxiety and depression in people with functional dyspepsia, a condition that causes stomach pain or discomfort without a clear physical cause. You may qualify if you have mild to moderate anxiety or depression alongside your stomach symptoms.
Xi’an, ShanxiAges 18–80 - NCT07190859Recruiting
Probiotic for crying and fussing in babies with colic
This trial tests if a probiotic (Limosilactobacillus reuteri) can help reduce crying and fussing in breastfed babies with colic. If your baby is 3-12 weeks old, has colic (cries or fusses 3+ hours a day), and is mostly breastfed, this study may be an option.
BurgasAges 3 weeks–3 months - NCT07231588RecruitingEarly Phase 1
Probiotic for stomach side effects during pelvic radiation
This trial tests an oral probiotic (a mix of 5 good bacteria) to see if it can reduce stomach and bowel side effects from pelvic radiation. It may help people undergoing radiation for certain pelvic cancers.
Cincinnati, OhioAges 18 years+ - NCT07241052Recruiting
Probiotic spray for cavities in kids
This study tests a probiotic spray that you use in your mouth to help stop cavities from getting worse and to prevent new ones. It is for children ages 7–10 who already have at least one cavity.
Hà Nội, Sơn TâyAges 7–10 - NCT07241182Recruiting
Mushroom extract supplement for lung cancer chemo patients
This study tests whether a supplement from a medicinal mushroom (Antrodia cinnamomea, also known as niu zhang zhi) can improve quality of life for people with lung cancer who are receiving platinum-based chemotherapy.
TaipeiAges 18–99 - NCT07252778RecruitingPhase 2/Phase 3
Probiotics for endurance athletes
This trial tests if taking a probiotic supplement for a short time can help athletes who do endurance sports like rowing. If you are a healthy athlete on a national team, this study might help you understand how probiotics affect performance.
Poznan, WielkopolskaAges 16–50 - NCT07256743RecruitingPhase 2
Testing a probiotic drink for gum health in healthy adults
This trial tests if taking a daily probiotic drink can help keep gums healthy in people without gum disease. You would be asked to stop using certain dental products during the study.
Toronto, OntarioAges 18–70 - NCT07258303Recruiting
Probiotic Spray for Gum Disease in Older Adults
This trial tests an oral spray that contains good bacteria (probiotics) to help prevent and treat gum disease in older adults. It may be a simple addition to your daily routine to support gum health.
Hanoi, HanoiAges 35 years+ - NCT07287306Recruiting
Probiotic study on gut health in healthy adults
This trial tests two probiotics, BLa80 and LRa05, to see how they affect the gut's natural bacteria and related substances. It may help understand how these probiotics support overall health.
Guangzhou, GuangdongAges 18–60 - NCT07334210Recruiting
Gut bacteria in sarcopenia and probiotic development
This study looks at gut bacteria differences between older adults with muscle loss (sarcopenia), healthy older adults, and younger adults. Results may help develop probiotics to support muscle health.
Seongnam-si, Gyeonggi-doAges 20–90 - NCT07341750Recruiting
Probiotic study for immune health in school-aged children
This trial tests whether a probiotic called Bacillus Coagulans SNZ 1969 can support the immune health of healthy children aged 6 to 12. Your child would take the probiotic or a placebo daily for a period while keeping their usual routine.
London, OntarioAges 6–12 - NCT07345585Recruiting
Probiotics for children with autism and stomach issues
This trial is testing if probiotics can help children with autism who also have stomach or bowel problems. The study gives children either probiotics or a placebo to see if the probiotics improve their stomach symptoms and overall well-being.
NaplesAges 4–12 - NCT07369830Recruiting
Probiotics for bowel function after rectal cancer surgery
This trial tests whether taking a probiotic supplement (Clostridium butyricum) can improve gut health and bowel function after surgery for very low rectal cancer. It may help patients who have a temporary ileostomy and are planning to have it reversed within 6 months.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07383441RecruitingPhase 3
Adding Biotherapy or Placebo to Standard Kidney Cancer Treatment
This trial tests whether adding a biotherapy (a special drug from a living source) or a placebo to standard treatments helps people with advanced kidney cancer. It may be a good option if your cancer hasn't been treated yet and you are in fairly good health.
Fayetteville, ArkansasAges 18 years+ - NCT07407894Recruiting
Probiotic study for healthy aging in midlife adults
This trial tests a probiotic supplement called iVS-1 to see if it can slow biological aging in healthy adults aged 40-75. Researchers want to learn if this probiotic may help support health as you age.
New Port Richey, FloridaAges 40–75 - NCT07429227Recruiting
Gut health and heart disease: a probiotic study
This trial tests whether natural extracts and probiotics can improve gut health in people who have had a recent heart attack (Acute Coronary Syndrome). It uses special exams to measure changes in gut bacteria.
Peschiera del Garda, VeronaAges 30–70 - NCT06974266Recruiting
Probiotic for high cholesterol in overweight adults
This trial tests a natural probiotic called Akkermansia muciniphila to see if it can help lower cholesterol in people who are overweight. It is for adults who have not been on cholesterol medication recently and are managing their levels with diet and exercise.
Zibo, ShandongAges 35–75 - NCT07490587RecruitingPhase 2
Probiotic study for healthy infant growth and allergy prevention
This trial tests a probiotic supplement (Bifidobacterium animalis subsp. lactis XLTG11) to see if it helps infants grow better and have fewer allergies. It is for healthy babies up to 3 years old who are at higher risk for allergies.
Pudong, Shanghai MunicipalityAges birth–3 years - NCT07497932Recruiting
Nutritional effects in heart surgery
This trial looks at whether adding a probiotic supplement before cardiovascular surgery can improve recovery. It studies the link between nutrition, gut health, and surgical outcomes.
New Taipei CityAges 50–80 - NCT07531875Recruiting
Probiotics to Help Treat Advanced Gum Disease
This trial tests whether taking probiotics (beneficial bacteria) alongside standard gum disease treatment can help reduce deep pockets in your gums and improve healing. You'd be asked to take probiotics as an add-on to the care you're already receiving.
Kuala Lumpur, Kuala LumpurAges 18 years+ - NCT07539805RecruitingPhase 2
Sertraline Plus Probiotic for Teen Depression
This study tests whether combining sertraline (an antidepressant) with a specific probiotic called Lactobacillus crispatus can safely and effectively treat depression in teenagers. The probiotic may help by improving gut health, which researchers believe could support mental health.
Longgang, Chongqing MunicipalityAges 12–18
Hear when a new Probiotic trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for probiotic?
- Yes. Clin2 currently lists 222 recruiting probiotic studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a probiotic trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a probiotic trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.